scholarly journals Short-term efficacy and safety of second generation bipolar transurethral vaporization of the prostate (B-TUVP) for large benign prostate enlargement: Results from a retrospective feasibility study

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261586
Author(s):  
Takeshi Fukazawa ◽  
Hiroki Ito ◽  
Masato Takanashi ◽  
Risa Shinoki ◽  
Tadashi Tabei ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urinary Retention ◽  
Lower Urinary Tract ◽  
Second Generation ◽  
Urine Volume ◽  
Efficacy And Safety ◽  
Short Term ◽  
Term Efficacy ◽  
Significant Difference ◽  
Lower Urinary

Background To investigate the efficacy and safety of a second-generation bipolar transurethral electro vaporization of the prostate (B-TUVP) with the new oval-shaped electrode for large benign prostatic enlargement (BPE) with prostate volume (PV) ≥100ml. Materials and methods 100 patients who underwent second-generation B-TUVP with the oval-shaped electrode for male lower urinary tract symptom (LUTS) or urinary retention between July 2018 and July 2020 were enrolled in this study. The patients’ characteristics and treatment outcome were retrospectively compared between patients with PV <100ml and ≥100ml. Results 17/41 (41.5%) cases of PV ≥100ml and 24/59 cases (40.7%) of PV <100ml were catheterised due to urinary retention. The duration of post-operative catheter placement and hospital-stay of PV ≥100ml (3.1±1.3 and 5.6±2.3 days) were not different from PV <100ml (2.7±1.2 and 5.0±2.4 days). In uncatheterised patients (N = 59), post-void residual urine volume (PVR) significantly decreased after surgery in both groups, however, maximum uroflow rate (Qmax) significantly increased after surgery only in PV <100ml but not in PV ≥100ml. Voiding symptoms and patients’ QoL derived from International Prostate Symptom Score (IPSS), IPSS-QoL (IPSS Quality of Life Index) and BPH Impact Index (BII) scores, significantly improved after B-TUVP in both groups. Catheter free status after final B-TUVP among patients with preoperative urinary retention was achieved in 18/24 (75.0%) and 14/17 (82.1%) cases in patient with <100ml and ≥100ml, respectively. There was no significant difference in post-operative Hb after B-TUVP, which was 97.0±5.4% of baseline for PV <100ml and 96.9±6.1% for PV ≥100ml and no TUR syndrome was observed. Conclusions This is the first study investigating short-term efficacy and safety of second-generation B-TUVP with the oval-shaped electrode on large BPE. B-TUVP appears to be effective and safe for treating moderate-to-severe lower urinary tract symptoms and urinary retention in patients with large BPE.

scholarly journals Nocturnal polyuria in men performing uroflowmetry for lower urinary tract symptoms

2021 ◽  
Vol 93 (4) ◽  
pp. 445-449
Author(s):  
Emanuele Rubilotta ◽  
Daniele Castellani ◽  
Marilena Gubbiotti ◽  
Matteo Balzarro ◽  
Giacomo Maria Pirola ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract Symptoms ◽  
Lower Urinary Tract ◽  
Urine Volume ◽  
Nocturnal Polyuria ◽  
Voiding Symptoms ◽  
Urinary Tract Symptoms ◽  
Significant Difference ◽  
The Impact ◽  
Lower Urinary

Purpose: To assess the prevalence of nocturnal polyuria (NP) in males performing uroflowmetry (UF) for lower urinary tract symptoms (LUTS), the impact of NP on UF outcomes, and bladder emptying, the association between NP and LUTS. Materials and methods: Men scheduled for UF were recruited in two Centres. Data collected were medical history, IPSS, UF, post-void residual urine volume (PVR), 3-day frequency-volume charts (FVC). The NP index was used to assess NP with a threshold of ≥ 33%. The relationship between NP and patient’s aging was assessed. Results: 162 patients were included in the analysis. Mean age was 70.95 ± 8.04 years. The prevalence of NP was 54.9% (89/162). 110 (68%) patients reported nocturia, and among these, NP was documented in 76 (69%). Nocturia was found in 85% (76/89) of the population with NP. Total IPSS score, IPSS items #1, #2 and #7 showed a significant difference in men with NP compared with those without. Maximum flow rate and PVR did not significantly change comparing men with or without NP. Mean voiding volume (VV) of the night-time micturitions was significantly higher in men with NP compared to those without NP (532.1 ± 275.6 ml vs 175 ± 168.7 ml respectively, p < 0001), while mean VV day-time micturitions and mean VV at UF did not change between groups.Conclusions: NP had a high prevalence in men with LUTS performing UF. Aged males were more commonly affected by NP. Data demonstrated a strong relationship between NP and nocturia and increased urinary frequency while voiding symptoms were poorly related to NP.

scholarly journals Effect of Premicturitional Bladder Volume on the Accuracy of Sonographic Assessment of Post Void Residual Urine Volume Measurement by Transabdominal Ultrasonography

2019 ◽  
Vol 18 (1) ◽  
pp. 30-36
Author(s):  
Roshani Pathak ◽  
Sunil Pradhan ◽  
Abhushan Tuladhar ◽  
Amit Shrestha ◽  
Riwaz Acharya
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract Symptoms ◽  
Lower Urinary Tract ◽  
Urine Volume ◽  
Bladder Volume ◽  
Residual Urine Volume ◽  
Residual Urine ◽  
Urinary Tract Symptoms ◽  
Significant Difference ◽  
Lower Urinary

Introduction: The Post Void Residual Urine volume (PVRU) is frequently significant in patients with bladder outflow obstruction; especially in patients with enlarged prostate and prostatism. The PVRU forms an important part of radiological investigation. Accurate measurement of the residual urine volume changes observed serially over a period of time may indicate clinical progress. The purpose of this study was to evaluate the effect of pre-void bladder volume on PVRU measurements. Methods: A prospective study was conducted to determine the accuracy of PVRU measurement in patient presenting with lower urinary tract symptoms (LUTS). 50 patients with LUTS were assessed ultrasonographically for pre void and post void bladder volumes during the study period of March 2017 till August 2017. PVRU measurements done in patients with bladder filling sensation at moderate to full capacity resulted in high estimations of PVRU which was quite significant in this study. Results: There was significant difference in the estimated PVRU between patients having high initial premicturitional volume (546±144 ml) than those with lower or moderate filling volume (261±58 ml) with mean of 173 ml and 35 ml respectively. The difference in estimated PVRU was highly significant with p value of < 0.0001. Conclusions: Measurement of pre void urinary bladder volume with an uncomfortably full bladder results in high post micturitional (PMRU) values even in most patients without lower urinary tract symptoms which may be false-positive. We advise that initial or pre-void urine volume be measured when the patient has initial or moderate feeling of bladder fullness.  

The short-term clinical efficacy of amitriptyline in the management of idiopathic feline lower urinary tract disease: A controlled clinical study

2003 ◽  
Vol 5 (3) ◽  
pp. 191-196 ◽  
Author(s):  
M Kraijer ◽  
J Fink-Gremmels ◽  
RF Nickel
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Controlled Study ◽  
Term Therapy ◽  
Long Term Effects ◽  
Short Term ◽  
Significant Difference ◽  
Before And After ◽  
Tract Disease ◽  
Lower Urinary

In a controlled study, the effects of amitriptyline compared with that of a placebo in cats suffering from idiopathic Feline Lower Urinary Tract Disease (FLUTD) have been investigated. Thirty-six animals were selected by veterinary practitioners and treated with a placebo or 10 mg amitriptyline once daily. All animals received concomitant antibiotic treatment. A total of 24 cats were included in the final assessment of the results. The severity of symptoms before and after treatment were compared between groups and showed no significant difference. Results indicated that the 7-day course of 10 mg amitriptyline was not effective in the treatment of idiopathic FLUTD. Thus, it is considered not to be beneficial as a short-term therapy where the therapeutic results depend on peripheral effects of the drug. Long-term effects may be expected 4 or more weeks after the start of therapy and need to be further investigated.

Voiding urosonography with second-generation contrast as a main tool for examining the upper and lower urinary tract in children. Pilot study

2016 ◽  
Vol 40 (3) ◽  
pp. 183-189 ◽  
Author(s):  
M. Fernández-Ibieta ◽  
C. Parrondo-Muiños ◽  
L.C. Fernández-Masaguer ◽  
E. Hernández-Anselmi ◽  
V. Marijuán-Sauquillo ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Pilot Study ◽  
Lower Urinary Tract ◽  
Second Generation ◽  
Main Tool ◽  
Voiding Urosonography ◽  
Lower Urinary

Possibilities of phytotherapy in patients with lower urinary tract symptoms due to benign prostate enlargement

2020 ◽  
Vol 10 (4) ◽  
pp. 317-323
Author(s):  
Adel S. Al-Shukri ◽  
Stanislav V. Kostyukov
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract Symptoms ◽  
Lower Urinary Tract ◽  
Prostate Gland ◽  
Urine Volume ◽  
Good Tolerability ◽  
Clinical Indicators ◽  
Urinary Tract Symptoms ◽  
Main Component ◽  
Lower Urinary

The results of the use of the phytopreparation Tadimax in the treatment of 60 men with mild and moderate lower urinary tract symptoms (LUTS) developed as a result of benign enlargement of the prostate gland are presented. The average age of the patients was 66.5 3.8 years. Tadimax was prescribed 2 tablets 3 times a day, in courses of 7 days with 7 day breaks for 3 months (a total of 6 courses). The data obtained indicate high efficacy and good tolerability of treatment. A decrease in the severity of LUTS was noted in 59 (96.6%) patients, which was accompanied by significant changes in objective clinical indicators: a decrease in residual urine volume and an increase in urine flow rate. Tadimax is a combined preparation, which includes extracts of several medicinal plants, and the main component is Crinum latifolium. The therapeutic effect of Tadimax is based on anti-inflammatory, antiproliferative and immunotropic action.

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