Second Primary Tumors Involving Non-small Cell Lung Cancer*

CHEST Journal ◽  
2005 ◽  
Vol 127 (4) ◽  
pp. 1152 ◽  
Author(s):  
Christianne S.J. Duchateau
CHEST Journal ◽  
2005 ◽  
Vol 127 (4) ◽  
pp. 1152-1158
Author(s):  
Christianne S.J Duchateau ◽  
Marcel P.M Stokkel

Lung Cancer ◽  
2003 ◽  
Vol 42 (1) ◽  
pp. 79-86 ◽  
Author(s):  
Steven M. Keller ◽  
Mark G. Vangel ◽  
Henry Wagner ◽  
Joan Schiller ◽  
Arnold Herskovic ◽  
...  

1992 ◽  
Vol 10 (10) ◽  
pp. 1519-1524 ◽  
Author(s):  
K H Heyne ◽  
S M Lippman ◽  
J J Lee ◽  
J S Lee ◽  
W K Hong

PURPOSE AND METHODS A review of 446 patients who were enrolled consecutively in small-cell lung cancer (SCLC) protocols was performed to identify in long-term survivors the frequency of new primary tumors and their clinical impact. RESULTS Forty-seven patients (10.5%) were identified to be free of disease at 2 years. Second primary tumors (SPTs) were diagnosed in 14 patients. The overall risk for developing an SPT was 10.3% per person-year. Actuarial risk at 8 years was 50.3% for an SPT. CONCLUSIONS In this review, SCLC showed one of the highest incidences of SPTs reported in aerodigestive tract malignancies. A long-term survivor was more likely to have an SPT than a relapse of SCLC. Consequently, the odds of death from an SPT compared with that from a relapse increased sharply from 1:13 within 4 years from diagnosis to 8:1 afterwards. Long-term survivors of SCLC would be excellent candidates for chemoprevention trials.


2021 ◽  
Vol 9 (6) ◽  
Author(s):  
Yuki Seike ◽  
Yukio Kawagishi ◽  
Akihito Bando ◽  
Ko Kimoto ◽  
Masato Hongo ◽  
...  

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