The Role of Vitamin D in the Prevention and Treatment of Osteoporosis

2004 ◽  
Vol 2 (4) ◽  
pp. 373-388 ◽  
Author(s):  
Mary E. Elliott ◽  
Nicole M. Nolan
2017 ◽  
Vol 20 (2) ◽  
pp. 69-75 ◽  
Author(s):  
Alexander S. Lutsenko ◽  
Liudmila Y. Rozhinskaya ◽  
Natalia V. Toroptsova ◽  
Zhanna E. Belaya

This article considers the role of calcium and vitamin D in body functions, with focus on skeletal system. We reviewed the results of studies on calcium and vitamin D supplementation worldwide and in Russia. According to these studies, there is insufficient dietary intake of these nutrients, irrespective of geographical, ethnic features and physiological conditions. We also reviewed the data on safety of calcium supplementations for urinary and cardiovascular systems, regimens and doses for vitamin D deficiency treatment in various age groups. The article also contains data on calcium, vitamin D and combined medications, available in Russia, for prevention and treatment of osteoporosis, with highlight on combined ones for better compliance and more convenient dosage frequency.


2002 ◽  
Vol 93 (1) ◽  
pp. 37-49 ◽  
Author(s):  
M.A Rodrı́guez-Martı́nez ◽  
E.C Garcı́a-Cohen

Maturitas ◽  
1997 ◽  
Vol 28 (1) ◽  
pp. 95
Author(s):  
J.L. Stock ◽  
L. Amantea ◽  
J.H. Overdorf ◽  
A.D. Samar ◽  
F.L. Pickens

1998 ◽  
Vol 4 (3) ◽  
pp. 96-101
Author(s):  
Michael Davies

Osteoporosis is now a treatable condition with an abundance of evidence for the efficacy of certain therapeutic strategies in preventing recurrent fractures. Most of these treatments act by improving bone mineral density through inhibition or reduction of bone resorption. For those women who are unable to take HRT; bisphosphonates, calcium, vitamin D, calcitriol or calcitonin may confer certain benefits. The bisphosphonate alendronate reduces both vertebral and long bone fractures, an effect seen soon after starting treatment. The changes in BMD and fracture reduction are less with the use of etidronate but it is certainly beneficial in reducing recurrent vertebral fracture. In the elderly calcium and vitamin D in combination can reduce non-vertebral and hip fracture and supplemental calcium of 1 g/day has been predicted to reduce bone loss and thus hip fractures by 22%. Evidence that calcitriol or calcitonin reduce fracture incidence is not good but calcitonin has been shown to have analgesic properties in those with acute vertebral fracture. The role of calcitriol is less certain and should be reserved for women with vertebral fractures in whom HRT or bisphosphonates cannot be used.


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