Oral glucose tolerance test in female Sprague Dawley rats administered with leaf extract of Momordica charantia

2014 ◽  
Vol 1 (1) ◽  
pp. 10-17
Author(s):  
O.A Oyesola ◽  
D.E Ehichioya ◽  
I.A Akinade ◽  
T.O Oyesola
Keyword(s):  
Glucose Tolerance ◽  
Oral Glucose Tolerance Test ◽  
Leaf Extract ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Momordica Charantia ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

Effects of Different Fasting Durations on Glucose and Lipid Metabolism in Sprague Dawley Rats

2019 ◽  
Vol 51 (08) ◽  
pp. 546-553
Author(s):  
Elin Rakvaag ◽  
Majbritt Dam Lund ◽  
Lars Wiking ◽  
Kjeld Hermansen ◽  
Søren Gregersen
Keyword(s):  
Glucose Tolerance ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Sprague Dawley ◽  
Glucose And Lipid Metabolism ◽  
Sprague Dawley Rats ◽  
Fat Tolerance Test ◽  
Fasting Duration

AbstractOvernight fasting of varying length is common practice when studying glucose and lipid metabolism in rats. However, prolonged fasting may influence insulin sensitivity, and it is unknown to which extent different fasting durations affect postprandial metabolism in rats. The purpose of this study was to investigate the effect of different fasting durations (6-, 12-, or 18-h) on fat tolerance and glucose tolerance in male Sprague Dawley rats. We also aimed to examine the effect of two test fats with different fatty acid composition on postprandial triglycerides. We conducted a fat tolerance test, where butterfat or rapeseed oil was administered in a crossover design (experiment 1), and an oral glucose tolerance test (experiment 2). Regarding the fat tolerance test, we found no effects of fasting duration on triglycerides or free fatty acids, whereas the 18-h fast resulted in reduced glucose and insulin area under the curves. We did not find differential effects of butterfat and rapeseed oil on the outcomes. We found decreased fasting insulin and homeostasis model assessment of insulin resistance (HOMA-IR), and increased beta-hydroxybutyric acid concentrations after 18-h fast compared with shorter fasting durations. Regarding the oral glucose tolerance test, both 12-h and 18-h fast resulted in greater peak insulin concentrations than 6-h fast, and peak glucose concentrations were higher after 18-h than 12-h fast. We found no effects of fasting on the insulin sensitivity index. In conclusion, extending the fasting duration had an impact on glucose metabolism in rats, but did not appear to influence fat tolerance.

Abstract #873: Association of Patterns in the Oral Glucose Tolerance Test and Different Clinical Features in Patients with Insulinoma

2005 ◽  
Vol 11 ◽  
pp. 28
Author(s):  
Fanny Rodriguez Vallejo ◽  
Juan Manuel Rios Torres ◽  
Francisco J. Gomez-Pérez ◽  
Juan A. Rull Rodrigo ◽  
Bernardo Pérez Enriquez
Keyword(s):  
Glucose Tolerance ◽  
Oral Glucose Tolerance Test ◽  
Clinical Features ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Oral Glucose Tolerance

Oral glucose tolerance test or HbA1c assessment of subjects with coronary disease verified by angiography

2016 ◽  
Author(s):  
Zivkovic Teodora Beljic ◽  
Biljana Jojic ◽  
Jelic Marina Andjelic ◽  
Goran Loncar ◽  
Aleksandar Davidovic ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Oral Glucose Tolerance Test ◽  
Coronary Disease ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Oral Glucose Tolerance
Sign in / Sign up

Export Citation Format

Share Document