Overweight and obesity among HIV-infected patients in a West African population

2017 ◽  
Vol 6 (2) ◽  
pp. 65-73
Author(s):  
O.O Okeke ◽  
O Ogunfowokan ◽  
L.A Moses ◽  
D Umoru
Keyword(s):  
Overweight And Obesity ◽  
West African ◽  
African Population

Risk of Hypotony After Primary Trabeculectomy With Antifibrotic Agents in a Black West African Population

1998 ◽  
Vol 7 (2) ◽  
pp. 82???85 ◽  
Author(s):  
Kuldev Singh ◽  
Sally Byrd ◽  
Peter R. Egbert ◽  
Donald Budenz
Keyword(s):  
West African ◽  
African Population ◽  
Antifibrotic Agents

scholarly journals Selective sweep near the In(2L)t inversion breakpoint in an African population of Drosophila melanogaster

2000 ◽  
Vol 76 (2) ◽  
pp. 149-158 ◽  
Author(s):  
FRANTZ DEPAULIS ◽  
LIONEL BRAZIER ◽  
SYLVAIN MOUSSET ◽  
ANNE TURBE ◽  
MICHEL VEUILLE
Keyword(s):  
Drosophila Melanogaster ◽  
High Frequency ◽  
Selection Effect ◽  
West African ◽  
African Population ◽  
Inversion Breakpoint ◽  
Major Haplotype ◽  
Selective Forces ◽  
Significant Deficit ◽  
Proximal Breakpoint

Chromosomal inversions largely inhibit recombination and may be associated with selective forces, such as hitch-hiking effects: the effect of positive selection on linked loci. A West African population of Drosophila melanogaster showed a high frequency (0·61) of the In(2L)t inversion. Departure from neutrality statistically associated with the inversion polymorphism was previously recorded at Su(H), a locus distant from the proximal breakpoint of the inversion. These results were consistent with hitch-hiking effects with recombination. The present sequence polymorphism survey involves a 1 kb fragment of the Vha68-1 locus located closer to the proximal breakpoint of the inversion. It shows a significant deficit of polymorphism with respect to divergence when compared with other loci studied in the same population, thus suggesting selective effects. Only 11 polymorphic sites are present in a sample of 20 chromosomes and these sites present a significant excess of rare-frequency variants. The major haplotype shows an unexpectedly high frequency. Our estimate of the background selection effect is not sufficient to account for the observed reduction of polymorphism. Intraspecific variation is structured between inverted and standard chromosomes; there are no shared polymorphisms but also no fixed differences between them. This pattern, together with that found on other loci previously studied near this inversion breakpoint, suggests hitch-hiking effects enhanced by the inversion.

Conversion and complications of elective laparoscopic cholecystectomy in a West African population

2018 ◽  
Vol 37 (4) ◽  
pp. 440
Author(s):  
AdewaleO Adisa ◽  
Olalekan Olasehinde ◽  
OlusegunI Alatise ◽  
BolanleO Ibitoye ◽  
AramideF Faponle ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
West African ◽  
African Population ◽  
Elective Laparoscopic Cholecystectomy

scholarly journals SARS-CoV-2 updates in a West African population and precautionary measures for sustaining quality antenatal care delivery

2020 ◽  
Vol 10 (2) ◽  
Author(s):  
Emmanuel Komla Senanu Morhe ◽  
Enoch Odame Anto ◽  
David Antony Coall ◽  
Eric Adua ◽  
Alexander Yaw Debrah ◽  
...  
Keyword(s):  
Antenatal Care ◽  
Care Delivery ◽  
West African ◽  
African Population ◽  
Precautionary Measures

scholarly journals Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Debasish Banerjee ◽  
Jacob Plange-Rhule ◽  
Nihil Chitalia ◽  
Kwabena Kumi ◽  
Frank B. Micah ◽  
...  
Keyword(s):  
Kidney Function ◽  
Pulse Pressure ◽  
Multivariate Regression Analysis ◽  
West African ◽  
African Population ◽  
Rural Village ◽  
Stage Renal Disease ◽  
End Stage ◽  
The Relationship ◽  
The City

Introduction. Hypertension, particularly pulse pressure [PP] is a major risk factor for end-stage renal disease. However, the effect of individual components of hypertension namely PP, systolic [SBP] and diastolic blood pressure [DBP] on kidney function, in the general African population is unknown. Methods. Data were collected on 944 participants [aged 40-75 y], living in villages in the area around the city of Kumasi, Ghana, on demographics, medications, height, weight, BP and 24-hour creatinine clearance (CrCl). Results. The demographic and clinical characteristics were: age 55(11) [mean (SD)] years, females 62%, rural village-dwellers 52%, diabetes 1·5%, BMI 21(4) kg/m2, 24-hourCrCl as a measure of glomerular filtration rate (GFR) 84(23) ml/min/1.73 m2. 29% had BP >140/90 mmHg; SBP and DBP were 125/74(26/14) mmHg, PP was 51(17) mmHg. PP increased with age by 0.55(95% CI: 0.46,0.64) mmHg/year. PP was higher (53(17) v 49(15) mmHg; p < 0.001) in the semiurban participants. GFR decreased both with increasing PP [-0.19 (-0.27,-0.10 ml/min/1.73 m2/mmHg; p < 0.001] and SBP [-0.09 (-0.14,-0.03) ml/min/1.73 m2/mmHg; p < 0.001] but there was no significant relationship with DBP [-0.04 (-0.15,0.06)]. After adjusting for SBP, the relationship between GFR and PP became steeper [-0.31 (-0.50,-0.12) ml/min/1.73 m2/mmHg; p < 0.001]. Using multivariate regression analysis that included PP, age, gender, BMI, only increasing age [-0.75 (-0.88,-0.62)] and decreasing BMI [0.49 (0.16,0.81)] were associated with decreased kidney function. Conclusions. In this homogeneous West-African population, PP increased with age and had a steeper relationship with declining kidney function than SBP or DBP.

Analysis of the CYP2D6 gene mutations and their consequences for enzyme function in a West African population

1999 ◽  
Vol 9 (6) ◽  
pp. 715-724 ◽  
Author(s):  
E-U. Griese ◽  
S. Asante-Poku ◽  
D. Ofori-Adjel ◽  
G. Mikus ◽  
M. Eichelbaum
Keyword(s):  
Gene Mutations ◽  
West African ◽  
African Population ◽  
Enzyme Function ◽  
Cyp2d6 Gene

Neurological morbidity among human T-lymphotropic-virus-type-1-infected individuals in a rural West African population

2008 ◽  
Vol 80 (1) ◽  
pp. 66-68 ◽  
Author(s):  
S Cooper ◽  
M Schim van der Loeff ◽  
S McConkey ◽  
M Cooper ◽  
R Sarge-Njie ◽  
...  
Keyword(s):  
Virus Type ◽  
West African ◽  
African Population ◽  
T Lymphotropic Virus ◽  
Neurological Morbidity

Osteometric Analysis of Sexual Dimorphism in the Sternal End of the Rib in a West African Population

1999 ◽  
Vol 44 (5) ◽  
pp. 12017J ◽  
Author(s):  
Edwin K. Wiredu ◽  
Robert Kumoji ◽  
Ramaswamy Seshadri ◽  
Richard B. Biritwum
Keyword(s):  
Sexual Dimorphism ◽  
West African ◽  
African Population
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