Confidence Assessment of an Absorption Model Using Limited Solubility and Permeability Data for 21 Drugs within a Dynamic Physiologically-Based Pharmacokinetic Simulator

Limited Solubility ◽

Physiologically Based ◽

Confidence Assessment ◽

Permeability Data

Using a Physiologically Based Pharmacokinetic Absorption Model to Establish Dissolution Bioequivalence Safe Space for Oseltamivir in Adult and Pediatric Populations

The AAPS Journal ◽

10.1208/s12248-020-00493-6 ◽

2020 ◽

Vol 22 (5) ◽

Author(s):

Lei Miao ◽

Youssef M. Mousa ◽

Liang Zhao ◽

Kimberly Raines ◽

Paul Seo ◽

...

Keyword(s):

Safe Space ◽

Absorption Model ◽

Physiologically Based ◽

Pediatric Populations

Evaluation of the Impact of In Vitro Release Alterations on Pharmacokinetics of Metoprolol Succinate Extended-Release (ER) Tablets Using the Physiologically Based Pharmacokinetic (PBPK) Absorption Model

10.26226/morressier.57d6b2b9d462b8028d88e144 ◽

2016 ◽

Author(s):

Tian Zhou

Keyword(s):

Extended Release ◽

In Vitro Release ◽

Absorption Model ◽

Metoprolol Succinate ◽

Physiologically Based ◽

The Impact ◽

Vitro Release

Quantitative analysis of the effect of controlled-release formulation on nonlinear gastrointestinal absorption of P-glycoprotein substrate talinolol using physiologically based pharmacokinetic absorption model

Journal of Drug Delivery Science and Technology ◽

10.1016/j.jddst.2019.05.006 ◽

2020 ◽

Vol 56 ◽

pp. 101057 ◽

Cited By ~ 1

Author(s):

Satoru Suzuki ◽

Yoshiyuki Shirasaka ◽

Ren Okada ◽

Akari Eguchi ◽

Hisanao Kishimoto ◽

...

Keyword(s):

Quantitative Analysis ◽

Controlled Release ◽

Gastrointestinal Absorption ◽

Absorption Model ◽

Release Formulation ◽

Controlled Release Formulation ◽

P Glycoprotein ◽

16 Using physiologically based pharmacokinetic (PBPK) modelling and SCHOLZ databank’s MDDI calculator (SDB-MDDI) to predict potential drug-drug interactions (DDI) of psychopharmaceuticals

10.1055/s-0040-1710124 ◽

2020 ◽

Author(s):

UR Lücht ◽

AK Geiben ◽

S Brune ◽

WU Scholz ◽

G Hempel

Keyword(s):

Drug Interactions ◽

Potential Drug ◽

Pbpk Modelling ◽

49. A Physiologically Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model for Chlorpyrifos Utilizing Neonatal Rats as Surrogates for Children

10.3320/1.2766399 ◽

2002 ◽

Author(s):

C. Timchalk ◽

A. Kousba ◽

T. Poet

Keyword(s):

Neonatal Rats ◽

Physiologically-based pharmacokinetic modeling of different size polyethylene glycol-coated gold nanoparticles in mice

10.1615/ihtc16.nmt.023362 ◽

2018 ◽

Author(s):

Linjing Deng ◽

Jinping Zhao ◽

Yufeng Miao ◽

Xu Hu ◽

Qihong Deng

Keyword(s):

Gold Nanoparticles ◽

Polyethylene Glycol ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically-Based Pharmacokinetic Modeling to Predict Changes in Drug Exposure during Pregnancy Using the Simcyp Simulator

10.26226/morressier.57d6b2b7d462b8028d88e945 ◽

2016 ◽

Author(s):

Suvarchala Kiranmai Avvari

Keyword(s):

Drug Exposure ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based ◽

Exposure During Pregnancy

Using Physiologically Based Pharmacokinetic (PBPK) Modeling as a Supportive Tool for Risk Assessment on the Critical Quality Attribute of a Generic Drug Product

10.26226/morressier.57d6b2bcd462b8028d88e03d ◽

2016 ◽

Author(s):

Fang Wu

Keyword(s):

Risk Assessment ◽

Generic Drug ◽

Drug Product ◽

Pbpk Modeling ◽

Quality Attribute ◽

Critical Quality Attribute ◽

Generic Drug Product ◽

Physiologically based pharmacokinetic model development for trazodone: application to paediatric dose projection

10.26226/morressier.5971be87d462b80290b534f2 ◽

2017 ◽

Author(s):

F. Calisti

Keyword(s):

Pharmacokinetic Model ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based ◽

Paediatric Dose

Physiologically‐Based Pharmacokinetic Modeling of Atorvastatin Incorporating Delayed Gastric Emptying and Acid‐to‐Lactone Conversion

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12447 ◽

2019 ◽

Vol 8 (9) ◽

pp. 664-675 ◽

Cited By ~ 5

Author(s):

Bridget L. Morse ◽

Jeffrey J. Alberts ◽

Maria M. Posada ◽

Jessica Rehmel ◽

Anil Kolur ◽

...

Keyword(s):

Gastric Emptying ◽

Delayed Gastric Emptying ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽