Early protection against measles infection in children Immunized with DPT-measles Vaccine at the Age of 4 Months

A study on early immunization with DPT-measles vaccine at the age of 4 months, was earned out during 1990 - 1991 on 348 babies at the Health Centre of Surabaya regency. Three hundred and forty eight babies were served as control. The results of the study reported here were : (a) By giving a mixture of DPT and measles at an early age (4 months of age) the coverage of measles immunization could be increased to 21% - 27%. (b) 1'wenty two percents of measles cases could be prevented. (c) The geometric mean titer using hemagglutination inhibition test of the babies who got a mixture DP7~measles vaccination at an early age was significantly higher than that of the GMT HI test of babies who got measles vaccination at the age of 9 months ( z test, p <0, 05 ) . The result of analysis of data showed that an early immunization program using a mixture of DPT-measles could protect babies under 9 months and thus prevent them from measles infection.

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Immune Response of Chickens to Six Strains of Newcastle Disease Virus as Measured by Hemagglutination-Inhibition Test

Avian Diseases ◽

10.2307/1588413 ◽

1969 ◽

Vol 13 (1) ◽

pp. 46

Author(s):

P. W. Chang ◽

V. J. Yates ◽

J. A. Pendleton ◽

T. D. Flanagan

Keyword(s):

Immune Response ◽

Newcastle Disease Virus ◽

Disease Virus ◽

Newcastle Disease ◽

Hemagglutination Inhibition ◽

Inhibition Test ◽

Hemagglutination Inhibition Test

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Measles Immunity After Revaccination: Results in Children Vaccinated Before 10 Months of Age

PEDIATRICS ◽

10.1542/peds.69.3.332 ◽

1982 ◽

Vol 69 (3) ◽

pp. 332-335

Author(s):

Calvin C. Linnemann ◽

Mark S. Dine ◽

Gary A. Roselle ◽

P. Anne Askey

Keyword(s):

Measles Virus ◽

Geometric Mean ◽

Lymphocyte Transformation ◽

First Year ◽

Cell Mediated Immunity ◽

Measles Vaccine ◽

Pediatric Practice ◽

Antibody Titers ◽

Measles Vaccination ◽

First Year Of Life

Measles immunity was studied in children in a private pediatric practice who had been revaccinated because they had received their primary measles vaccination before 1 year of age. Antibody was measured in 72 of these children who had received the first injection of live measles virus vaccine at <10 months of age, and the second at >1 year of age. Of the 72 children, 29 (40%) had no detectable antibody and the geometric mean titer for the group was approximately 1:4. Of the children with low antibody titers, 15 were given a third injection of measles vaccine and five (33%) still did not respond. Cell- mediated immunity as indicated by lymphocyte transformation to measles antigen was measured in 11 of the children. Five (45%) had responses to measles antigen, but the responses did not correlate with the presence or absence of antibody. This study confirms the observation that revaccination is unsuccessful in many children who received measles vaccine in the first year of life, and shows that even a third injection of vaccine may fail to produce a significant antibody response.

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