Developmental delay in 3-month-old low birth weight infants with hyperbilirubinemia

2013 ◽  
pp. 228-231
Author(s):  
Wiradharma Wiradharma ◽  
I Gusti Ayu Trisna Windiani ◽  
Ekawaty Lutfia Haksari
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Developmental Delay ◽  
Low Birth Weight Infants

scholarly journals Identification of Growth Patterns in Low Birth Weight Infants from Birth to 5 Years of Age: Nationwide Korean Cohort Study

2021 ◽  
Vol 18 (3) ◽  
pp. 1206
Author(s):  
So Jin Yoon ◽  
Joohee Lim ◽  
Jung Ho Han ◽  
Jeong Eun Shin ◽  
Soon Min Lee ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Developmental Delay ◽  
Growth Parameters ◽  
Growth Patterns ◽  
Health Check ◽  
Low Birth Weight Infants ◽  
Weight Group ◽  
Poor Growth ◽  
Birth Weight Group

This study aimed to investigate the nationwide growth pattern of infants in Korea according to the birth-weight group and to analyze the effect of growth on development. A total of 430,541 infants, born in 2013 and who received the infant health check-up regularly from 6 months to 60 months of age, were included. The weight, height, head circumferences percentiles, and neurodevelopment using screening tests results were compared among the birth-weight groups. Using longitudinal analysis, the study found a significant difference in height, weight, and head circumference, respectively, according to age at health check-up, birth weight group, and combination of age and birth weight (p < 0.001). The growth parameters at 60 months of age showed a significant correlation with those at 6 months of age especially in extremely low birth weight infants. The incidence of suspected developmental delay was significantly higher in infants with growth below the 10th percentiles than in those with growth above the 10th percentiles. Among 4571 (1.6%) infants with suspected developmental delay results at 60 months of age, birth weight, sex, and poor growth parameters were confirmed as associated factors. This nationwide Korean study shows that poor growth and neurodevelopment outcomes persisted among low-birth-weight infants at 60 months of age. Our findings provide guidance for developing a nationwide follow-up program for infants with perinatal risk factors in Korea.

scholarly journals Developmental delay in 3-month-old low birth weight infants with hyperbilirubinemia

2013 ◽  
Vol 53 (4) ◽  
pp. 228 ◽  
Author(s):  
Wiradharma Wiradharma ◽  
I Gusti Ayu Trisna Windiani ◽  
Ekawaty Lutfia Haksari
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Developmental Delay ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Low Birth Weight Infants ◽  
Factors Associated ◽  
Relative Risks ◽  
The Impact ◽  
Learning Data

Backgrourui Developmental delay may be due to a variety offactors occurring during the prenatal, perinatal, or postnatalperiods, one of which is hyperbilirubinemia.Objective To evaluate the impact ofhyperbilirubinemia on infantdevelopmental delay.Methods A prospective cohort study was conducted from March toJuly 2011. Subjects were low birth weight infants with and withouthyperbilirubinemia. Developmental delay was measured using theMullen Scales of Early Learning. Data was analyzed by Chi squaretest and relative risks were calculated. Logistic regression analysiswas performed to assess factors associated with developmentaldelay. Differences were considered statistically significant for Pvalues < 0.05.Results Forty-six low birth weight infants were enrolledin this study, 23 with hyperbilirubinemia and 23 withouthyperbilirubinemia. The relative risk (RR) for developmentaldelay in the hyperbilirubinemia group was 2.08 (95%CI 0.51 to8 .40). Multivariate analysis revealed that hyperbilirubinemia didnot significantly influence developmental delay (RR 1.45; 95%CI0.29 to 7.31). However, small for gestational age with or withouthyperbilirubinemia significantly influenced developmental delay(RR 12.13; 95%CI 2.43 to 60.56).Conclusion Hyperbilirubinemia in low birth weight infants isn ot a risk factor for developmental delay at the age of 3 months.However, being small for gestational age with or withouthyperbilirubinemia significantly influences the likelihood ofdevelopmental delay.

scholarly journals Increased incidence of intraventricular hemorrhage and developmental delay in cocaine-exposed, very low birth weight infants

1994 ◽  
Vol 124 (5) ◽  
pp. 765-771 ◽  
Author(s):  
Lynn T. Singer ◽  
Toyoko S. Yamashita ◽  
Suzanne Hawkins ◽  
Diane Cairns ◽  
Jill Baley ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Developmental Delay ◽  
Intraventricular Hemorrhage ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants

Isolated mental developmental delay in very low birth weight infants: Association with prolonged doxapram therapy for apnea

2001 ◽  
Vol 139 (6) ◽  
pp. 832-837 ◽  
Author(s):  
Con Sreenan ◽  
Phillip C. Etches ◽  
Nestor Demianczuk ◽  
Charlene M.T. Robertson
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Developmental Delay ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants

scholarly journals Study of Developmental Delay and Its Related Factors in Low Birth Weight Infants

2018 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mahmoud Soltani ◽  
Seyed Mostajab Razavi Ardekani ◽  
Atila Erami ◽  
Zahra Eskandari Kootahi ◽  
Negar Yazdani
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Developmental Delay ◽  
Low Birth Weight Infants ◽  
Related Factors

scholarly journals The Prognosis of Refractory Hypotension and Severe Intraventricular Hemorrhage in Very Low Birth Weight Infants

2021 ◽  
Author(s):  
Seok Hwang-Bo ◽  
Yu-Mi Seo ◽  
Moon-Yeon Oh ◽  
Soo-Ah Im ◽  
YoungAh Youn
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Developmental Delay ◽  
Intraventricular Hemorrhage ◽  
Very Low Birth Weight ◽  
Periventricular Leukomalacia ◽  
Pulmonary Hemorrhage ◽  
Low Birth Weight Infants ◽  
Neurodevelopmental Outcomes ◽  
Refractory Hypotension

Abstract Background: The increased survival rate among very low birth weight infants has resulted in a higher risk for developing neurocomplications such as intraventricular hemorrhage (IVH), periventricular leukomalacia (PVL) and adverse neurodevelopmental outcomes.Purpose: We examined refractory hypotension experienced within a week of life in association with severe IVH (grades 3-4) among very low birth weight infants (VLBWIs).Method: Between Jan 2014 and Dec 2017, the clinical data of 191 VLBWIs admitted were retrospectively reviewed. Of a total of 191 VLBWIs, 71.2% (136/191) had IVH, and 28.7% (55/191) had severe IVH.Results: The VLBWI with severe IVH group (grade 3-4) presented with a significantly lower gestational age along with higher use of postnatal hydrocortisone for refractory hypotension. Resuscitation at delivery, pulmonary hemorrhage, neonatal seizure, and periventricular leukomalacia (PVL) were significantly more frequent in the severe IVH group (p<0.05). Higher mortality occurred in the VLBWI with severe IVH group (p<0.001). The multivariable logistic regression analysis consistently showed that refractory hypotension within a week of life and neonatal seizures were significantly associated with severe IVH. Those in the severe IVH and refractory hypotension groups had significantly lower composite cognitive, language, motor, and Bayley Scales of Infant and Toddler Development III scores at corrected 18 months.Those in the severe IVH and refractory hypotension groups showed significant developmental delay.Conclusion: Refractory hypotension within a week of life and seizures were consistently associated with severe IVH. VLBWI who experienced refractory hypotension within a week of life may indicate a more vulnerable perinatal settings with a higher risk for developmental delay.

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