scholarly journals COMPARATIVE STUDY OF CLINICAL EFFICACY AND SIDE EFFECTS OF ADAPALENE 0.1% GEL AND BENZOYL PEROXIDE 2.5% GEL AS MONOTHERAPIES AND COMBINATION THERAPY IN FACIAL ACNE: INDIAN PERSPECTIVE

2014 ◽  
Vol 3 (14) ◽  
pp. 3786-3798
Author(s):  
Adarsh Gowda ◽  
Sanmitha S K ◽  
Satish K S
Keyword(s):  
Side Effects ◽  
Combination Therapy ◽  
Comparative Study ◽  
Benzoyl Peroxide ◽  
Clinical Efficacy ◽  
Indian Perspective ◽  
Facial Acne

scholarly journals A comparative study on treatment of keloid with triamcinolone versus 5-fluorouracil and triamcinolone

2020 ◽  
Vol 7 (5) ◽  
pp. 1373
Author(s):  
C. V. Praveen Kumar Reddy ◽  
Surekha A.
Keyword(s):  
Side Effects ◽  
Combination Therapy ◽  
Comparative Study ◽  
Plastic Surgery ◽  
Relapse Rate ◽  
Combination Regimen ◽  
Parallel Group Study ◽  
Parallel Group

Background: The study was done to assess and compare the treatment of keloids with intralesional triamcinolone and combination of 5-fluorouracil and triamcinolone. Despite various options available, there is no universally accepted treatment for keloids. Our objective was to compare two regimens and establish superiority in terms of objective and subjective outcomesMethods: A randomized parallel group study conducted in the Department of Plastic Surgery from January 2017 to June 2019. A total of 80 patients were taken with 40 each group.Results: Though there was improvement in both regimens, this was more significant with combination regimen especially with vascularity, pliability, decrease in height and faster relief of symptoms like pain and itching.Conclusions: Both were effective in treatment of keloids; triamcinolone alone was having relapse rate and combination therapy was more effective with faster results and few side effects. 

Clinical efficacy and safety of the combination therapy of peginterferon alpha and ribavirin in cirrhotic patients with HCV infection

2010 ◽  
Vol 16 (1) ◽  
pp. 38 ◽  
Author(s):  
Hong Ryeol Cheong ◽  
Hyun Young Woo ◽  
Jeong Heo ◽  
Ki Tae Yoon ◽  
Dong Uk Kim ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Clinical Efficacy ◽  
Hcv Infection ◽  
Efficacy And Safety ◽  
Cirrhotic Patients

EVALUATION OF CLINICAL EFFICACY AND SIDE EFFECTS OF ROTAVIRUS VACCINE

2020 ◽  
Vol 76 (1) ◽  
Author(s):  
Ali Ulas TUGCU ◽  
Figen Sahin ◽  
Gulendam Bozdayi ◽  
Fatma Nur Aksakal ◽  
Gulcin Alp ◽  
...  
Keyword(s):  
Side Effects ◽  
Clinical Efficacy ◽  
Rotavirus Vaccine

scholarly journals Impact of immunogenicity on clinical efficacy and toxicity profile of biologic agents used for treatment of inflammatory arthritis in children compared to adults

2021 ◽  
Vol 13 ◽  
pp. 1759720X2110026
Author(s):  
Chinar R. Parikh ◽  
Jaya K. Ponnampalam ◽  
George Seligmann ◽  
Leda Coelewij ◽  
Ines Pineda-Torra ◽  
...  
Keyword(s):  
Side Effects ◽  
Clinical Efficacy ◽  
Inflammatory Arthritis ◽  
Biologic Agents ◽  
Adult Patients ◽  
Therapeutic Drug ◽  
Biologic Drugs ◽  
Therapeutic Implications ◽  
The Impact ◽  
First Time

The treatment of inflammatory arthritis has been revolutionised by the introduction of biologic treatments. Many biologic agents are currently licensed for use in both paediatric and adult patients with inflammatory arthritis and contribute to improved disease outcomes compared with the pre-biologic era. However, immunogenicity to biologic agents, characterised by an immune reaction leading to the production of anti-drug antibodies (ADAs), can negatively impact the therapeutic efficacy of biologic drugs and induce side effects to treatment. This review explores for the first time the impact of immunogenicity against all licensed biologic treatments currently used in inflammatory arthritis across age, and will examine any significant differences between ADA prevalence, titres and timing of development, as well as ADA impact on therapeutic drug levels, clinical efficacy and side effects between paediatric and adult patients. In addition, we will investigate factors associated with differences in immunogenicity across biologic agents used in inflammatory arthritis, and their potential therapeutic implications.

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