Prevalence of Nerve Dysfunction in Individuals in Satara District Suffering from Chronic Neck Pain - A Nerve Conduction Velocity Study

2021 ◽  
Vol 10 (29) ◽  
pp. 2150-2155
Author(s):  
Anushka Vijay Rane ◽  
Prachi Kulkarni ◽  
Trupti S. Yadav

BACKGROUND Chronic neck pain is one of the common and painful musculoskeletal conditions. Determining the prevalence of nerve impairment in chronic neck pain patients is faced with various challenges such as individual perception and coping patterns of pain and likelihood to seek and receive treatment. We wanted to determine the prevalence of nerve impairment in patients of chronic neck pain and estimate the occupation, age, and gender wise involvement of nerve impairment in chronic neck pain patients. METHODS Population in and around Karad diagnosed with chronic neck pain by an orthopaedician fulfilling the inclusion criteria with prior consent were taken for the study. In the first half of the study, participants were assessed based on a questionnaire and a clinical assessment using Upper Limb Tension Tests following which the participants were assessed using nerve conduction velocity studies. RESULTS Participants having chronic neck pain and showing nerve dysfunctions were 32.14 %. Based on F min, frequency of nerve dysfunction within age groups showed the highest percentage that was 10.72 % in the age group of 39 - 42 years. Higher involvement was observed in males than females which was 23.21 %. Occupation wise nerve involvement for nerve dysfunction showed physically demanding occupations which had higher percentage of 14.28 %. CONCLUSIONS This study shows large population of chronic neck pain with no symptoms of nerve involvement but having nerve dysfunction and were not receiving any treatment for their condition thereby allowing it to progress into a radiculopathy. KEY WORDS Chronic Neck Pain, NCV Study, Cervical Radiculopathy, F Min Latency

Author(s):  
Riccardo Marvulli ◽  
Giancarlo Ianieri ◽  
Grazia Devenuto ◽  
Marta Falcicchio ◽  
Giulia A. Gallo ◽  
...  

Background and Objective: Carpal tunnel syndrome (CTS) is the most common form of nerve entrapment. Clinically, various signs and symptoms compare due to overexposure to mechanical vibrations transmitted to the wrist bones and cartilage, resulting in compression of the sensory and motor nerve fibers of median nerve. Early symptoms include nocturnal paresthesia and electromyography reveals reduced sensory nerve conduction velocity. Aim of this study was to evaluate the efficacy of a dietary integrator composed of acetyl-L-carnitine, α-lipoic acid,quercetin, bromelain, pantothenic acid, C and B1 and B2 and B6 and B12 vitamins in patients with early (minimal) carpal tunnel syndrome. Methods: 36 patients (28 female and 8 male) with early CTS characterized by sensory nerve demyelination and inflammation of the transverse carpal ligament. Patients were divided into two groups, group A (18 patients received physical therapy) and group B (18 patients, received physical therapy and an oral integrator). Clinical (sleep quality questionnaire to measure severity of paresthesia) and neurophysiological assessment (Sensory Nerve Conduction Velocity) performed at baseline, and then at 30 and 60 days after treatment. Results: Sleep quality and Sensory Nerve Conduction Velocity data analysis show improvement in both groups at 30 and 60 days, with statistically difference between them in both time of analysis. Conclusions: In the early CTS, with sensory fibers damage, use of dietary integrator, such as Micronil Dol®, composed composed of acetyl-L-carnitine, α-lipoic acid,quercetin, bromelain, pantothenic acid, C and B1 and B2 and B6 and B12 vitamins can be effective in quick recovery of median nerve sensory.


2021 ◽  
Vol 9 (1) ◽  
pp. e001698
Author(s):  
Haifa Maalmi ◽  
Kristiaan Wouters ◽  
Hans H C M Savelberg ◽  
Jeroen H P M van der Velde ◽  
Jos P H Reulen ◽  
...  

IntroductionDistal sensorimotor polyneuropathy (DSPN) is common in people with diabetes but is also found in pre-diabetes. Peripheral nerve myelin damage, which can be assessed by reduced nerve conduction velocity (NCV), is an essential feature of DSPN. Emerging evidence indicates that the development of DSPN may involve the activation of the immune system. However, available studies have mainly investigated circulating immune mediators, whereas the role of immune cells remains unclear. Therefore, we aimed to test whether leukocyte subsets are associated with NCV.Research design and methodsThis cross-sectional study analyzed data from 850 individuals (of whom 252 and 118 had type 2 diabetes and pre-diabetes, respectively) of the Maastricht Study. NCV was measured in the peroneal and tibial motor nerves and the sural sensory nerve and summed to calculate a standardized NCV sum score. Associations between percentages of leukocyte subsets and NCV sum scores were estimated using linear regression models adjusted for demographic, lifestyle, metabolic and clinical covariates.ResultsAfter adjustment for covariates, higher percentages of basophils and CD4+ T cells were associated with lower NCV (p=0.014 and p=0.005, respectively). The percentage of CD8+ T cells was positively associated with NCV (p=0.022). These associations were not modified by glucose metabolism status (all pinteraction >0.05). No associations were found for monocytes, eosinophils, neutrophils, lymphocytes, total T cells, Treg cells and B cells.ConclusionsThe associations of basophils, CD4+ and CD8+ T cells with NCV suggest that cell types from both innate and adaptive immunity may be implicated in the development of DSPN.


1999 ◽  
Vol 129 (1) ◽  
pp. 207-213 ◽  
Author(s):  
Alain Gerbi ◽  
Jean-Michel Maixent ◽  
Jean-Luc Ansaldi ◽  
Michele Pierlovisi ◽  
Thierry Coste ◽  
...  

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