scholarly journals Assessment of Traffic Policemen Exposure To Benzene by Using Trans, Trans-Muconic Acid Biomarker in Ahvaz City, Iran

2020 ◽  
Vol 1 (4) ◽  
pp. 16-21
Author(s):  
Neisi Abdolkazem ◽  
Mahmoudi Parviz ◽  
Kayedi Neda ◽  
Behroozi Hamid
Keyword(s):  
Biological Indicator ◽  
Muconic Acid ◽  
Traffic Policemen ◽  
Benzene Concentration ◽  
The Relationship ◽  
Congested Areas

Benzene is known as an environmental and industrial pollutant. One way to check the amount of exposure to benzene is to measure its metabolites in the urine. Trans, Trans-Muconic Acid which is one of its metabolites is also as a biological indicator of exposure to benzene. In this study, the relationship between the amount of this biomarker and the environmental benzene concentration was investigated in two groups of policemen working outdoors in the traffic-congested areas and indoor in the same area. The results showed that the highest amount of benzene was in Salman Farsi Station at 4.44 ppm. At the same time, the biomarker measured in the urine showed 127.20 μg / L, which was the highest amount. In addition, the amount of benzene in the outdoor was approximately 3 times more than indoor and the amount of biomarker measured in outdoor employees was two times more than indoors ones. In general, wherever there was more benzene, the biomarker would also show a higher amount.

scholarly journals The Relationship of Benzene Exposure to Trans, Trans-Muconic Acid and Blood Profile of Shoe Workers in Romokalisari Surabaya, Indonesia

2019 ◽  
Vol 7 (5) ◽  
pp. 816-823 ◽  
Author(s):  
Abdul Rohim Tualeka ◽  
Yashwant Pathak ◽  
Dwi Ananto Wibrata ◽  
Bahrul Ilmi ◽  
Ahsan Ahsan ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
P Value ◽  
Research Subjects ◽  
Muconic Acid ◽  
Cross Sectional ◽  
Blood Profile ◽  
Benzene Exposure ◽  
Shoe Industry ◽  
The Relationship ◽  
Shoe Workers

Benzene is a hazardous ingredient for health. Benzene is used as a latex glue solvent in the shoe industry. The purpose of this study was to analyze the relationship between benzene exposure with trans, trans-muconic acid and the blood profile of shoe workers in Romokalisari Surabaya. This study is a cross-sectional study conducted in the shoe industry in Romokalisari Surabaya with a number of research subjects of 20 shoe workers. Data collection was carried out by measuring benzene levels conducted at 8 measurement points in Surabaya Romokalisari, taking workers' blood, measuring body weight and conducting interviews with respondents. Data were analyzed using correlation tests. The results showed that there was no relationship between benzene levels with t, t-MA (p-value = 0.205), there was no relationship between benzene RQ and t, t-MA (p-value = 0.271) and there was no relationship between the ECR and blood profile of workers in Romokalisari. There is no correlation between benzene levels and t,t-MA, RQ and t,t-MA and there is no relationship between the ECR and all the profile parameters of the blood workers in Romokalisari. Benzene, Blood Profile, Shoe Worker, t,t-MA

scholarly journals Factors Affecting Urinary tt-Muconic Acid Detection among Benzene Exposed Workers at Gasoline Stations

2019 ◽  
Vol 16 (21) ◽  
pp. 4209 ◽  
Author(s):  
Sunisa Chaiklieng ◽  
Pornnapa Suggaravetsiri ◽  
Norbert Kaminski ◽  
Herman Autrup
Keyword(s):  
High Performance ◽  
Multiple Logistic Regression Analysis ◽  
Muconic Acid ◽  
Factors Affecting ◽  
Spot Urine ◽  
Flame Ionization ◽  
Benzene Concentration ◽  
Exposed Workers ◽  
Fuel Nozzle ◽  
Low Exposure

Trans, trans-muconic acid (tt-MA) is a metabolite that is widely used as a biomarker to identify low exposure to benzene, a human carcinogen. This study aimed to investigate occupational factors related to the urinary tt-MA detection of benzene exposed workers in gasoline stations. Spot urine samples were collected and analyzed for tt-MA using a high performance liquid chromatography. Additional data were collected via subject interviews using a structured questionnaire. The personal benzene concentration was measured and analyzed by gas chromatography with a flame ionization detector. Results showed that, among the 170 workers, tt-MA was detected in 24.7% of workers and the concentration ranged from 23.0 to 1127.8 µg/g creatinine. Over 25% of those detections possessing tt-MA exceeding the recommended 500 µg/g creatinine was safe. A multiple logistic regression analysis identified that factors significantly associated with the detectable tt-MA were having no other part-time jobs (ORadj = 4.2), personal benzene concentrations of 0.05 ppm or higher (ORadj = 10.3), close to fuel nozzle during refuelling (ORadj = 93.7), and no job training (ORadj = 2.74). Safety training is recommended for those tt-MA detected workers or under a reference benzene concentration of 0.05 ppm or higher. The proposed reference of occupational action level to benzene exposure is 0.05 ppm and compliance could be assessed tt-MA for biomonitoring of those benzene exposed workers.

Evaluation of the relationship between TNFα, sTNFR1, sTNFR2, sIL2R, IL6, neopterin with disease activity in ankylosing spondylitis

2018 ◽  
Vol 43 (5) ◽  
pp. 487-494
Author(s):  
Nergiz Zorbozan ◽  
Süleyman Demir ◽  
Veli Çobankara
Keyword(s):  
Ankylosing Spondylitis ◽  
Disease Activity ◽  
Biological Indicator ◽  
Tnf Blockers ◽  
Patient Groups ◽  
Group 3 ◽  
Inflammatory Drugs ◽  
The Relationship ◽  
Active Patients ◽  
Group 1

Abstract Objective We aimed to evaluate the relationship among TNFα, sTNFR1, sTNFR2, sIL2R, IL6, neopterin and disease activity in ankylosing spondylitis (AS). Materials and methods TNFα, sTNFR1, sTNFR2, sIL2R, IL6 and neopterin were measured in patients and controls. Patients were grouped according to disease activity and medication. Results Neopterin and sTNFR1 were not different while TNFα, sTNFR2, sIL2R and IL6 were high in patients than controls. There was no difference between active and inactive patients for TNFα, sIL2R and IL6. sTNFR2 was significantly lower in active patients. There was no relationship between CRP positivity and disease activity. AS patient groups are; 1: TNF blockers, 2: nonsteroidal anti-inflammatory drugs (NSAIDs), 3: disease modifying anti-rheumatic drugs (DMARDs), 4: TNF blockers and NSAIDs, 5: DMARDs and NSAIDs. sTNFR2 was significantly lower in active patients than in inactive, in Group 1. ESR levels were significantly lower in inactive patients compared to active in group 3 and 4. There was no significant association between CRP positivity and disease activity. Conclusion According to our study, CRP is insufficient in evaluating AS disease activity. ESR can be useful in evaluating the disease activity. sTNFR2 might be useful as a biological indicator of disease activity in AS treated with TNF inhibitors alone.

scholarly journals Kadar Timbal (Pb) Pada Rambut dan Kuku Polisi Lalu Lintas di Kota Pekanbaru dan Kota Bengkalis

2015 ◽  
Vol 2 (2) ◽  
pp. 121
Author(s):  
Wahyu Hardinsyah Putra ◽  
Bintal Amin ◽  
Sofia Anita
Keyword(s):  
Atomic Absorption ◽  
Natural Sciences ◽  
Atomic Absorption Spectrophotometer ◽  
Low Level ◽  
Traffic Police ◽  
Traffic Policemen ◽  
The Relationship ◽  
The City

This research was conducted in the city of Bengkalis and Pekanbaru from June toAugust 2014, with the aim to analyze the concentrations of lead (Pb) in hair andnails of traffic policemen and to analyze the relationship between the length ofemployment with concentrationss of lead contained in hair and nails of traffic police in thecity of Bengkalis and Pekanbaru. The samples were analyzed in the Laboratory of PhysicalChemistry of the Faculty of Mathematics and Natural Sciences, University of Riau by usingAAS (Atomic Absorption Spectrophotometer). Results of the research showedthat lead concentrations in hair and nails of traffic policemen in the city of Pekanbaruwere 13.36 and 2.11 ppm resprctively and categorized as medium and low level ofcontamination. Meanwhile, lead concentrations in hair and nails of traffic policemen in thecity of Bengkalis were 21.81 and 2.56 ppm which were also categorized as medium and lowlevel of contamination respectively. Concentrations of Lead in the hair of policemen relationto length of employment in Bengkalis were 14.37; 13.09 and 25.29 ppm for <3, 3-5 and >5years respectively. Lead concentrations in nails of traffic policemen at both locations for awork period <3, 3-5 and >5 years were 1.58, 2.70 and 2.71ppm respectively. Average Leadconcentrations in the hair (17.56 ppm) was higher than in nails (2.33 ppm), however theirconcentrations were statistically not different. 

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