Treatment of Gastric Varices with 2-octyl-cyanoacrylate Glue Injection

2005 ◽  
Vol 100 ◽  
pp. S349-S350
Author(s):  
Ann M. Chen ◽  
Kenneth F. Binmoeller
Keyword(s):  
Gastric Varices ◽  
Cyanoacrylate Glue ◽  
Glue Injection

scholarly journals Non-cirrhotic portal hypertension: current concepts and modern management

2016 ◽  
Vol 43 (3) ◽  
pp. 170-176
Author(s):  
Md Ismail Patwary ◽  
Matiur Rahman ◽  
Kaushik Mojumder
Keyword(s):  
Portal Hypertension ◽  
Portal Vein ◽  
Variceal Bleeding ◽  
Gastric Varices ◽  
Idiopathic Portal Hypertension ◽  
Endoscopic Sclerotherapy ◽  
Cyanoacrylate Glue ◽  
Portal Fibrosis ◽  
Vascular Origin ◽  
Glue Injection

Non-cirrhotic portal hypertension (NCPH) is a heterogeneous group of liver disorders of vascular origin, leading to portal hypertension (PHTN) in the absence of cirrhosis.The lesions are generallyvascular, either in the portal vein, its branches or in the peri-sinusoidal area. The majority of diseases included in the category of NCPH are well-characterized disease entities where PHTN is a late manifestation. Two diseases that present only with features of PHTN and are common in developing countries are non-cirrhotic portal fibrosis (NCPF) and extrahepatic portal vein obstruction (EHPVO). Non-cirrhotic portal fibrosis is a syndrome of obscure etiology, characterized by ‘obliterative-portovenopathy’ leading to PHT, massive splenomegaly and well-tolerated episodes of variceal bleeding in young adults from low socioeconomic backgrounds, having near normal hepatic functions. In some parts of the world, NCPFis called idiopathic portal hypertension in Japan or ‘hepatoportalsclerosis’in USA. Because 85–95% of patient with NCPF and EHPVO present with variceal bleeding, treatment involves management with endoscopic sclerotherapy (EST) or variceal ligation (EVL). These therapies are effective in approximately 90–95% of patients. Gastric varices are another common cause of upper gastrointestinal bleeding in these patients and these can be managed with cyanoacrylate glue injection or surgery. The prognosis of patients with NCPF is good and 5 years survival in patients in whom variceal bleeding can be controlled has been reported to be approximately 95–100%.Bangladesh Med J. 2014 Sep; 43 (3): 170-176

scholarly journals Endoscopic ultrasound coil placement of gastric varices: Emerging modality for recurrent bleeding gastric varices

2014 ◽  
Vol 05 (01) ◽  
pp. 024-026
Author(s):  
Yogesh Harwani ◽  
Mahesh Kumar Goenka ◽  
Vijay Rai ◽  
Usha Goenka
Keyword(s):  
Case Report ◽  
Endoscopic Ultrasound ◽  
Standard Of Care ◽  
Gastric Varices ◽  
Recurrent Bleeding ◽  
High Complication Rate ◽  
Cyanoacrylate Glue ◽  
Acute Variceal Bleeding ◽  
Probable Source ◽  
Glue Injection

AbstractGastric varices are the probable source of bleeding in 10-36% of patients, with acute variceal bleeding and carry high mortality and rebleeding rates. Till date, cyanoacrylate glue injection is considered as the standard of care but has high complication rate. Endoscopic ultrasound (EUS) guided coil placement is a new emerging technique of management of gastric varices. In this case report, we detail the EUS guided coil placement for management of gastric varices after failed glue injections.

T1457: EUS-Guided Treatment of Gastric Varices With Combined Intravariceal Coiling and Cyanoacrylate Glue Injection

2010 ◽  
Vol 71 (5) ◽  
pp. AB282
Author(s):  
Jin Kim ◽  
Janak N. Shah ◽  
Fernando Marson ◽  
Thomas M. Desimio ◽  
Kenneth F. Binmoeller
Keyword(s):  
Gastric Varices ◽  
Cyanoacrylate Glue ◽  
Glue Injection

scholarly journals Gastric Variceal Obliteration By Cyanoacrylate Glue Injection

2012 ◽  
Vol 7 (2) ◽  
pp. 44-46
Author(s):  
SMB Hussain ◽  
MR Hossain ◽  
MM Rahman ◽  
S Parvin ◽  
MD Hossain
Keyword(s):  
Case Report ◽  
Gastrointestinal Bleeding ◽  
Variceal Bleeding ◽  
Gastric Varices ◽  
Oesophageal Varices ◽  
Cyanoacrylate Glue ◽  
Back Ground ◽  
Successful Control ◽  
Glue Injection

Introduction: Rupture Gastric varices (GVs) can lead to catastrophic gastrointestinal bleeding, though it is much less in number than that of rupture oesophageal varices (OVs). Successful haemostasis of such bleeding is difficult specially in the back ground of non availability of appropriate drugs and instruments. Case Report: Introduction of intra-variceal injection of cyanoacrylate glue since 1980s has changed the scenario, it is cheaper and effective in controlling GVs related bleeding. A case of successful control of gastric variceal bleeding is reported. DOI: http://dx.doi.org/10.3329/jafmc.v7i2.10397 JAFMC 2011; 7(2): 44-46

Endoscopic Cyanoacrylate Glue Injection in Management of Large Gastric Varices That Have Not Bled

2016 ◽  
Vol 111 ◽  
pp. S148-S149
Author(s):  
Subhash Chandra ◽  
Adrian Holm ◽  
Rami El Abiad ◽  
Henning Gerke
Keyword(s):  
Gastric Varices ◽  
Cyanoacrylate Glue ◽  
Glue Injection

scholarly journals Efficacy and safety of combined endoscopic cyanoacrylate injection and balloon-occluded retrograde transvenous occlusion (BRTOcc) of gastrorenal shunts in patients with bleeding gastric fundal varices

2020 ◽  
Author(s):  
Fateh Bazerbachi ◽  
Akira Dobashi ◽  
Swarup Kumar ◽  
Sanjay Misra ◽  
Navtej S Buttar ◽  
...  
Keyword(s):  
Adverse Events ◽  
Gastric Varices ◽  
High Rate ◽  
Efficacy And Safety ◽  
Cyanoacrylate Glue ◽  
Serious Adverse Events ◽  
Gastroesophageal Varices ◽  
Life Threatening ◽  
Glue Embolization

Abstract Background Endoscopic cyanoacrylate (glue) injection of fundal varices may result in life-threatening embolic adverse events through spontaneous gastrorenal shunts (GRSs). Balloon-occluded retrograde transvenous occlusion (BRTOcc) of GRSs during cyanoacrylate injection may prevent serious systemic glue embolization through the shunt. This study aimed to evaluate the efficacy and safety of a combined endoscopic–interventional radiologic (BRTOcc) approach for the treatment of bleeding fundal varices. Methods We retrospectively analysed the data of patients who underwent the combined procedure for acutely bleeding fundal varices between January 2010 and April 2018. Data were extracted for patient demographics, clinical and endoscopic findings, technical details, and adverse events of the endoscopic–BRTOcc approach and patient outcomes. Results We identified 30 patients (13 [43.3%] women; median age 58 [range, 25–92] years) with gastroesophageal varices type 2 (53.3%, 16/30) and isolated gastric varices type 1 (46.7%, 14/30) per Sarin classification, and median clinical and endoscopic follow-up of 151 (range, 4–2,513) days and 98 (range, 3–2,373) days, respectively. The median volume of octyl-cyanoacrylate: Lipiodol injected was 7 (range, 4–22) mL. Procedure-related adverse events occurred in three (10.0%) patients, including transient fever, non-life-threatening pulmonary glue embolism, and an injection-site ulcer bleed. Complete gastric variceal obturation was achieved in 18 of 21 patients (85.7%) at endoscopic follow-up. Delayed variceal rebleeding was confirmed in one patient (3.3%) and suspected in two patients (6.7%). Although no procedure-related deaths occurred, the overall mortality rate was 46.7%, primarily from liver-disease progression and co-morbidities. Conclusion The combined endoscopic–BRTOcc procedure is a relatively safe and effective technique for bleeding fundal varices, with a high rate of variceal obturation and a low rate of serious adverse events.

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