Wide-area Transepithelial Sampling (WATS-3D) Brush Biopsy as an Adjunct to Forceps Biopsy (FB) for the Detection of Barrettʼs Metaplasia and Dysplasia after Endoscopic Therapy

2013 ◽  
Vol 108 ◽  
pp. S32
Author(s):  
Danielle Marino ◽  
Donald Tsynman ◽  
Vivek Kaul
Keyword(s):  
Endoscopic Therapy ◽  
Wide Area ◽  
Forceps Biopsy ◽  
Brush Biopsy

scholarly journals S0405 Wide Area Transepithelial Sampling in Adjunct to Forceps Biopsy in Post Treatment Barret’s Esophagus: Increasing Diagnostic Yield

2020 ◽  
Vol 115 (1) ◽  
pp. S201-S202
Author(s):  
Andrea S. Pagan ◽  
Liege Diaz ◽  
Yadis Arroyo ◽  
Carlos Bertran-Rodriguez ◽  
Farina Klocksieben ◽  
...  
Keyword(s):  
Diagnostic Yield ◽  
Post Treatment ◽  
Wide Area ◽  
Forceps Biopsy ◽  
Barret's Esophagus

scholarly journals Wide-area transepithelial sampling in adjunct to forceps biopsy increases the absolute detection rates of Barrett’s oesophagus and oesophageal dysplasia: a meta-analysis and systematic review

2020 ◽  
Vol 7 (1) ◽  
pp. e000494
Author(s):  
Vishnu Charan Suresh Kumar ◽  
Prateek Harne ◽  
Venkata Suresh Patthipati ◽  
Abinash Subedi ◽  
Umair Masood ◽  
...  
Keyword(s):  
Systematic Review ◽  
Detection Rate ◽  
Meta Analysis ◽  
Relative Increase ◽  
Wide Area ◽  
Detection Rates ◽  
Absolute Increase ◽  
Forceps Biopsy ◽  
Barrett's Oesophagus ◽  
The Absolute

BackgroundWide-area transepithelial sampling (WATS) is a new technique that uses an abrasive brush to obtain samples from a larger surface area of the oesophagus. Studies have shown promising results that WATS in adjunct to forceps biopsy (FB) increases the detection rate of Barrett’s oesophagus (BE) as well as oesophageal dysplasia (ED). We conducted a systematic review and meta-analysis to compare the detection rates of BE and ED between FB and WATS in adjunct to FB.MethodsA Literature search was done using electronic databases, including PubMed, Embase, Scopus, Cochrane and CINAHL from inception to 26 April 2020. A meta-analysis comparing detection rates of WATS in adjunct to FB versus FB using the random-effects model was done using RevMan V.5.3.ResultsPooled data from 20 392 endoscopies across 11 studies showed an absolute increase in detection of 16% (95% CI 0.10% to 0.22%, p<0.00001). A relative increase of 1.62 was seen in detection rates of BE (95% CI 1.28 to 2.05, p<0.0001) when WATS was used with FB with the number needed to test (NNT) of 6.1 patients. For ED, a 2% absolute increase (95% CI 0.01 to 0.03, p=0.001) in additional diagnostic yield from WATS. A relative increase of 2.05 was seen in the detection rate of ED (95% CI 1.42 to 2.98, p=0.0001) yielding an NNT of 50 patients.ConclusionOur study shows that WATS, as an adjunct to FB, improves both the absolute detection rate and relative detection rate of both BE and ED as compared to FB alone.

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