S0400 Utility of Baseline Impedance Ratio Measured During High Resolution Impedance Manometry in Identification of Erosive Esophagitis and/or Barrett’s Esophagus

Background : Obesity is correlated with several comorbidities, including gastroesophageal reflux disease. Its main complications are detectable by endoscopy: erosive esophagitis and Barrett's esophagus. Aim : To correlate erosive esophagitis and hiatal hernia with the degree of body mass index (BMI). Method : Was performed a retrospective analysis of 717 preoperative endoscopic reports of bariatric patients. Fifty-six (8%) presented hiatal hernia, being 44 small, nine medium and five large. Esophagitis was classified by Los Angeles classification. Results : There was no correlation between the presence and dimension of hiatal hernia with BMI. One hundred thirty-four (18.7%) patients presented erosive esophagitis. Among them, 104 (14.5%) had esophagitis grade A; 25 (3.5%) grade B; and five (0.7%) grade C. When considering only the patients with erosive esophagitis, 77.6% had esophagitis grade A, 18.7% grade B and 3.7% grade C. Were identified only two patients with Barrett's esophagus (0,28%). Conclusion : There was a positive correlation between the degree of esophagitis with increasing BMI.

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Sa1818 African Americans Do Not Develop Barrett's Esophagus Following Erosive Esophagitis

Gastroenterology ◽

10.1016/s0016-5085(14)61087-8 ◽

2014 ◽

Vol 146 (5) ◽

pp. S-302-S-303

Author(s):

Ahmad AlKaddour ◽

Camille McGaw ◽

Rama Hritani ◽

Carlos Palacio ◽

Juan C. Munoz ◽

...

Keyword(s):

African Americans ◽

Barrett’S Esophagus ◽

Barrett's Esophagus ◽

Erosive Esophagitis

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The Frequencies of Gastroesophageal and Extragastroesophageal Symptoms in Patients with Mild Erosive Esophagitis, Severe Erosive Esophagitis, and Barrett’s Esophagus in Taiwan

Gastroenterology Research and Practice ◽

10.1155/2013/480325 ◽

2013 ◽

Vol 2013 ◽

pp. 1-6 ◽

Cited By ~ 3

Author(s):

Sung-Shuo Kao ◽

Wen-Chih Chen ◽

Ping-I Hsu ◽

Seng-Kee Chuah ◽

Ching-Liang Lu ◽

...

Keyword(s):

Los Angeles ◽

Barrett’S Esophagus ◽

Barrett's Esophagus ◽

Epigastric Pain ◽

Erosive Esophagitis ◽

Chi Square ◽

Asian Patients ◽

Body Sensation ◽

Chi Square Test ◽

Extraesophageal Symptoms

Background. Gastroesophageal reflux disease (GERD) may present with gastroesophageal and extraesophageal symptoms. Currently, the frequencies of gastroesophageal and extragastroesophageal symptoms in Asian patients with different categories of GERD remain unclear.Aim. To investigate the frequencies of gastroesophageal and extragastroesophageal symptoms in patients with mild erosive esophagitis, severe erosive esophagitis, and Barrett’s esophagus of GERD.Methods. The symptoms of symptomatic subjects with (1) Los Angeles grade A/B erosive esophagitis, (2) Los Angeles grade C/D erosive esophagitis, and (3) Barrett’s esophagus proven by endoscopy were prospectively assessed by a standard questionnaire for gastroesophageal and extragastroesophageal symptoms. The frequencies of the symptoms were compared by Chi-square test.Result. Six hundred and twenty-five patients (LA grade A/B: 534 patients; LA grade C/D: 37 patients; Barrett’s esophagus: 54 patients) were assessed for gastroesophageal and extragastroesophageal symptoms. Patients with Los Angeles grade A/B erosive esophagitis had higher frequencies of symptoms including epigastric pain, epigastric fullness, dysphagia, and throat cleaning than patients with Los Angeles grade C/D erosive esophagitis. Patients with Los Angeles grade A/B erosive esophagitis also had higher frequencies of symptoms including acid regurgitation, epigastric acidity, regurgitation of food, nausea, vomiting, epigastric fullness, dysphagia, foreign body sensation of throat, throat cleaning, and cough than patients with Barrett’s esophagus.Conclusion. The frequencies of some esophageal and extraesophageal symptoms in patients with Los Angeles grade A/B erosive esophagitis were higher than those in patients with Los Angeles grade C/D erosive esophagitis and Barrett’s esophagus. The causes of different symptom profiles in different categories of GERD patients merit further investigations.

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Comparison of clinical characteristics among Barrett’s esophagus, erosive esophagitis and non-erosive reflux disease

World Chinese Journal of Digestology ◽

10.11569/wcjd.v17.i31.3249 ◽

2009 ◽

Vol 17 (31) ◽

pp. 3249

Author(s):

Jun Zhang ◽

You-Qing Xu ◽

Zhao-Xu Yang

Keyword(s):

Barrett’S Esophagus ◽

Reflux Disease ◽

Barrett's Esophagus ◽

Clinical Characteristics ◽

Erosive Esophagitis

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Low Levels of Gastrin 17 are Related with Endoscopic Findings of Esophagitis and Typical Symptoms of GERD

Journal of Gastrointestinal and Liver Diseases ◽

10.15403/jgld-2952 ◽

2021 ◽

Author(s):

Francesco Di Mario ◽

Pellegrino Crafa ◽

Marilisa Franceschi ◽

Kryssia Rodriguez-Castro ◽

Gianluca Baldassarre ◽

...

Keyword(s):

Primary Care ◽

Barrett’S Esophagus ◽

Barrett's Esophagus ◽

Care Setting ◽

Primary Care Setting ◽

Erosive Esophagitis ◽

Serum Levels ◽

Referral Center ◽

Low Levels ◽

Gerd Symptoms

Background and Aims: In clinical practice, most patients with symptoms suggestive of gastroesophageal reflux disease (GERD) undergo esophago-gastro-duodenoscopy (EGD), despite its low sensitivity in detecting reflux stigmata. Gastrin 17 (G-17) has been proposed to be related with GERD, due to the negative feedback between acid secretion and this hormone. We assessed the clinical usefulness of fasting G-17 serum determination for a non-invasive diagnosis of GERD in patients with typical symptoms. Methods: We consecutively enrolled patients complaining of typical GERD symptoms in two different settings: a single referral center and a primary care setting. Control groups consisted of dyspeptic patients. All subjects underwent assessment of serum levels of G-17 and EGD. Results: At the academic hospital, 100 GERD patients (n=89 with erosive esophagitis and 11 with Barrett’s esophagus) had statistically significant low levels of G-17 as compared with 184 dyspeptic patients (1.7±1.2 pg/L vs 8.9±5.7 pg/L p<0.0001). Similarly, in the primary care setting, 163 GERD patients had statistically significant low levels of G-17 as compared with 132 dyspeptic patients (0.5±0.2 pg/L vs. 4.0±2.6 pg/L, p<0.0001). Moreover, in the primary care setting, no statistically significant differences were found for G-17 levels between patients with erosive and non-erosive reflux pattern (0.4±0.2 vs 0.7±0.3; p=0.08). In primary care, the accuracy of G-17 less than 1 pg/L to diagnose non-invasively GERD was 94.3%. Conclusions: Low levels of G-17 were detected in patients with erosive esophagitis and Barrett’s esophagus in a referral center and in patients with typical GERD symptoms in a sample of patients from a primary care setting.

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