S1008 Outcomes of Endoscopic Retrograde Cholangiopancreatography (ERCP) in Non-ST Elevation Myocardial Infarction (NSTEMI) Patients—A National Inpatient Sample Study (2012-2018)

Introduction: In infective endocarditis (IE), embolization to the coronary arteries is an uncommon phenomenon but can contribute to transmural infarction presenting as ST elevation myocardial infarction (STEMI). Due to limited date, we intend to evaluate the clinical outcomes in hospitalized patients with STEMI with and without underlying IE. Hypothesis: Morbidity and morbidity exponentiates in STEMI with comorbid IE when compared to without IE. Methods: Patients with primary diagnosis of STEMI with and without IE were identified by querying the Healthcare Cost and Utilization (HCUP) database, specifically, National Inpatient Sample for year 2013 and 2014 based on ICD9 codes Results: During 2013 and 2014, a total of 117, 386 patients were admitted with the principle diagnosis of STEMI, out of whom 305 had comorbid IE. There was an increased in-hospital mortality (27.5% vs 10.8%, increased length of stay (14 vs 5 days), acute kidney injury (44.9% vs 18.7%), stroke (23.6% vs 3%), aortic valve replacement (9.5% vs 0.3%), mitral valve replacement (0.2%-5.2%), sepsis (50% vs 6%) and acute respiratory failure (36.7% vs 16.7%) in patients with STEMI with IE when compared to patients with STEMI and without comorbid IE. STEMI without IE had higher number of angiographies (58.7% vs 25.9%) and percutaneous coronary interventions (50.7% vs 14.4%) during their hospital course when compared to STEMI with IE. Conclusions: We conclude that hospitalized STEMI patients with concomitant diagnosis of IE are at higher risk of in-hospital mortality, increased LOS, AKI, stroke, valve replacements, and acute respiratory failure. Clinical trials that compare optimal interventions in these patients would be needed in future.

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PREDICTORS OF IN-HOSPITAL MORTALITY IN WOMEN WITH ST ELEVATION MYOCARDIAL INFARCTION: INSIGHTS FROM THE NATIONAL INPATIENT SAMPLE

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(16)30511-3 ◽

2016 ◽

Vol 67 (13) ◽

pp. 510

Author(s):

Hend Mansoor ◽

Islam Elgendy

Keyword(s):

Myocardial Infarction ◽

Hospital Mortality ◽

St Elevation Myocardial Infarction ◽

National Inpatient Sample ◽

St Elevation

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In-hospital outcomes and prevalence of comorbidities in patients with ST-elevation myocardial infarction with and without infective endocarditis: insight from the National Inpatient Sample (2013–2014)

Journal of Investigative Medicine ◽

10.1136/jim-2020-001519 ◽

2020 ◽

pp. jim-2020-001519

Author(s):

Michael Albosta ◽

Shakeel M Jamal ◽

Asim Kichloo ◽

Farah Wani ◽

Beth Bailey ◽

...

Keyword(s):

Myocardial Infarction ◽

Respiratory Failure ◽

Infective Endocarditis ◽

Hospital Mortality ◽

Acute Respiratory Failure ◽

Valve Replacement ◽

Hospitalized Patients ◽

St Elevation Myocardial Infarction ◽

National Inpatient Sample ◽

St Elevation

In patients with infective endocarditis (IE), ST-elevation myocardial infarction (STEMI) is an uncommon phenomenon. Due to limited data, we intend to evaluate the clinical outcomes in hospitalized patients with STEMI with and without underlying IE. Mortality and morbidity are exponentially worse in STEMI with concomitant IE when compared with without IE. Patients with primary diagnosis of STEMI with and without IE were identified by querying the Healthcare Cost and Utilization Project database of the National Inpatient Sample for the years 2013 and 2014 based on International Classification of Diseases, Ninth Revision codes. During 2013 and 2014, a total of 117,386 patients were admitted with the principle diagnosis of STEMI, out of whom 305 had comorbid IE. There was a significantly increased in-hospital mortality (27.5% vs 10.8%), length of stay (LOS) (14 days vs 5 days), acute kidney injury (AKI; 44.9% vs 18.7%), stroke (23.6% vs 3%), aortic valve replacement (9.5% vs 0.3%), mitral valve replacement (0.2%–5.2%), sepsis (50% vs 6%) and acute respiratory failure (36.7% vs 16.7%) in patients with STEMI with IE when compared with patients with STEMI and without comorbid IE. STEMI without IE had a higher number of angiographies (58.7% vs 25.9%) and percutaneous coronary interventions (50.7% vs 14.4%) during the hospital course when compared with STEMI with IE. In conclusions, hospitalized patients with STEMI with a concurrent diagnosis of IE are at higher risk of in-hospital mortality, increased LOS, AKI, stroke, valve replacements, and acute respiratory failure.

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Effect of diabetic ketoacidosis on the outcomes of ST-elevation myocardial infarction: An analysis of national inpatient sample

IJC Heart & Vasculature ◽

10.1016/j.ijcha.2019.100384 ◽

2019 ◽

Vol 24 ◽

pp. 100384

Author(s):

Dhrubajyoti Bandyopadhyay ◽

Arvind R. Devanabanda ◽

Ramyashree Tummala ◽

Sandipan Chakraborty ◽

Adrija Hajra ◽

...

Keyword(s):

Myocardial Infarction ◽

Diabetic Ketoacidosis ◽

St Elevation Myocardial Infarction ◽

National Inpatient Sample ◽

St Elevation

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Impact of Obstructive Sleep Apnea on In-Hospital Outcomes of Patients with Non-ST Elevation Myocardial Infarction

Hearts ◽

10.3390/hearts2010009 ◽

2021 ◽

Vol 2 (1) ◽

pp. 119-126

Author(s):

Sakiru Oyetunji Isa ◽

Oluwole Adegbala ◽

Olajide Buhari ◽

Mahin Khan ◽

Orimisan Adekolujo ◽

...

Keyword(s):

Myocardial Infarction ◽

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Hospital Mortality ◽

The United States ◽

St Elevation Myocardial Infarction ◽

National Inpatient Sample ◽

Hospital Outcomes ◽

Obstructive Sleep ◽

St Elevation

Background: Obstructive sleep apnea (OSA) is one of the most common breathing disorders. There are uncertainties about its impact on the in-hospital outcomes of patients who suffer acute coronary syndromes. We studied the largest publicly available all-payer inpatient healthcare database in the United States (National Inpatient Sample) to determine the effects of obstructive sleep apnea on the in-hospital outcomes of patients admitted with non-ST elevation myocardial infarction (NSTEMI). Methods: All adult patients (age ≥ 18) admitted primarily for NSTEMI between September 2010 and September 2015 were identified in the National Inpatient Sample. They were then categorized into those with OSA and those without OSA. The main outcome was in-hospital mortality. Propensity scoring and logistic regression models were created to determine the outcomes. Results: There were 1,984,432 patients with NSTEMI (weighted estimates), 123,551 (6.23%) of who had diagnosed OSA while 1,860,881 (93.77%) did not. In-hospital mortality was significantly lower in the OSA group [2.61% vs. 3.53%, adjusted odd ratio (aOR) 0.73 and confidence interval (CI) (0.66–0.81)]. Patients with OSA were also less likely to require coronary artery bypass surgery: 13.85% and 12.77% (p-value 0.0003). The patients with OSA had higher mean hospital costs compared to the patients who did not have OSA: $17,326 vs. $16,984, adjusted mean ratio (aMR) 1.02; CI (1.01–1.02). Conclusion: In-hospital mortality was lower in NSTEMI patients with diagnosed OSA compared to patients without diagnosed OSA. This appears to contrast with the widely recognized adverse effects of OSA on the cardiovascular system.

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