scholarly journals S2057 Dysphagia Refractory to Pharmacotherapy in a Myasthenic Patient

2021 ◽  
Vol 116 (1) ◽  
pp. S890-S890
Author(s):  
Aleem Ali ◽  
Radhika Sharma ◽  
Herit Vachhani ◽  
Ron Schey
Keyword(s):  
2013 ◽  
Vol 5 (1) ◽  
pp. 4 ◽  
Author(s):  
Rita Sonzogni ◽  
Lorenzo Novellino ◽  
Alberto Benigni ◽  
Ilaria Busi ◽  
Magda Khotcholava ◽  
...  

Myasthenia gravis (MG) is an autoimmune disease marked by weakness of voluntary musculature. Medical and surgical therapy of adult myasthenia is well documented. There is little pediatric surgical evidence, only a few case reports being available. The aim of this paper is to verify whether the surgical and anesthesiological techniques can warrant an early and safe discharge from the operating room. The secondary aim is to assess the presence of perioperative indicators that can eventually be used as predictors of postoperative care. During the years 2006-2009, 10 pediatric patients were treated according to a surgical approach based on video assisted thoracoscopic extended thymectomy (VATET). Standard preoperative evaluation is integrated with functional respiratory tests. Anesthetic induction was made with propofol and fentanyl/remifentanyl and maintenance was obtained with sevoflurane/desflurane/propofol ± remifentanyl. A muscle relaxant was used in only one patient. Right or left double-lumen bronchial tube (Ruesch Bronchopart® Carlens) placement was performed. Six patients were transferred directly to the surgical ward while 4 were discharged to the intensive care unit (ICU); ICU stay was no longer than 24 h. Length of hospital stay was 4.4±0.51 days. No patient was readmitted to the hospital and no surgical complications were reported. Volatile and intravenous anesthetics do not affect ventilator weaning, extubation or the postoperative course. Paralyzing agents are not totally contraindicated, especially if short-lasting agents are used with neuromuscular monitoring devices and new reversal drugs. Perioperative evaluation of the myasthenic patient is mandatory to assess the need for postoperative respiratory support and also predict timely extubation with early transfer to the surgical department. Availability of new drugs and of reversal drugs, the current practice of mini-invasive surgical techniques, and the availability of post anesthesia care units are the keys to the safety and successful prognosis of patients affected by MG who undergo thymectomy.


1991 ◽  
Vol 4 (6) ◽  
pp. xi
Author(s):  
B.K. Ong ◽  
N Willcox ◽  
P Wordsworth ◽  
D Beeson ◽  
A Vincent ◽  
...  

1991 ◽  
Vol 11 (7) ◽  
pp. 18-26 ◽  
Author(s):  
E Chipps

Crisis in the myasthenic patient is a life-threatening event. The expertise of the critical care nurse is crucial to the prevention of complications and the return of the patient to a functional capacity.


2020 ◽  
Vol 8 (7) ◽  
Author(s):  
Chu‐Pin Pai ◽  
Chih‐Ming Lin ◽  
Yi‐Chen Yeh ◽  
Chien‐Sheng Huang ◽  
Biing‐Shiun Huang

1997 ◽  
Vol 150 ◽  
pp. S317
Author(s):  
M.R.R. Gonçalves ◽  
E.R. Barbosa ◽  
P.E. Marchiori ◽  
A.A. Zambon

2011 ◽  
Vol 25 (2) ◽  
pp. 316-317 ◽  
Author(s):  
Helena Argiriadou ◽  
Kyriakos Anastasiadis ◽  
Evanthia Thomaidou ◽  
Dimitrios Vasilakos

Neurology ◽  
1997 ◽  
Vol 48 (Supplement 5) ◽  
pp. 70S-75S ◽  
Author(s):  
S. A. Mayer

Neurology ◽  
2020 ◽  
pp. 10.1212/WNL.0000000000011239
Author(s):  
Robert M. Feibel

Henry R. Viets (1890–1969) was both a noted neurologist and medical historian. While at Harvard Medical School, from which he graduated in 1916, he attracted the attention of Harvey Cushing who directed Viets into these disciplines. Cushing arranged for Viets to take a fellowship in Oxford in the year after his graduation. With Cushing's recommendation, he lived with Sir William and Lady Osler and did research with the famous neurologist Sir Charles Sherrington. Viets was in London in 1935 when he heard about the remarkable success of Mary Walker in treating myasthenia gravis, first with physostigmine and then with neostigmine (Prostigmin). Securing an ampoule of this drug, he took it to the Massachusetts General Hospital where he was an attending neurologist and in March 1935 injected it into a myasthenic patient with great success. He established the first Myasthenia Gravis Clinic in the world and was a pioneer in the treatment of this once obscure disease: he evaluated hundreds of patients and published many articles on myasthenia. He continued this association for over 30 years. Under the tutelage of Cushing and Osler, Viets became a medical historian and bibliophile, publishing hundreds of articles and several books on many different subjects in the history of medicine. He was the President of the American Association for the History of Medicine and curator of the Boston Medical Library that eventually joined with the Harvard Medical School Library. Viets served on the Editorial Board of the New England Journal of Medicine for 40 years.


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