The degree of reliability of data obtained using a computer registry of patients with non-insulin-dependent diabetes mellitus

The main problem in analysis of the register of diabetes mellitus is evaluation of the reliability of data and the probability of extrapolating the results to a population of patients in the studied region. Our task was to assess the efficacy of diagnostic methods used in a region. Study of the prevalence of diabetic retinopathy and neuropathy by referent tests revealed poor sensitivity of methods for diagnosis of these complications in patients with insulin-dependent diabetes mellitus (IDDM) in the Mytischi region; hence, the prevalence of diabetic retinopathy and neuropathy might be higher than recorded in IDDM register. Analysis confirmed the usefulness of active detection of early stages of complicated IDDM by screening (examination of the fundus oculi, detection of microalbuminuria and vibration sensitivity) for reflecting the true incidence of complications and timely therapy. Detection of numerous patients with IDDM at the phase of diabetes decompensation necessitates revision of preventive and therapeutic measures. High incidence of hypoglycemic reactions among IDDM patients necessitates their more active prevention, specifically, training IDDM patients to practice automonitoring methods.

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Progression of Diabetic Retinopathy after Pancreas Transplantation for Insulin-Dependent Diabetes Mellitus

New England Journal of Medicine ◽

10.1056/nejm198801283180403 ◽

1988 ◽

Vol 318 (4) ◽

pp. 208-214 ◽

Cited By ~ 266

Author(s):

Robert C. Ramsay ◽

Frederick C. Goetz ◽

David E.R. Sutherland ◽

S. Michael Mauer ◽

Leslie L. Robison ◽

...

Keyword(s):

Diabetes Mellitus ◽

Diabetic Retinopathy ◽

Pancreas Transplantation ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Insulin Dependent

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Incidence of insulin-dependent diabetes mellitus: An epidemiological study

Problems of Endocrinology ◽

10.14341/probl12150 ◽

1994 ◽

Vol 40 (4) ◽

pp. 61-64

Author(s):

Ye. V. Trofimenko ◽

N. B. Lebedev ◽

N. V. Gubanov ◽

Ye. N. Zlobina ◽

I. I. Dedov

Keyword(s):

Diabetes Mellitus ◽

Insulin Dependent Diabetes Mellitus ◽

Epidemiological Studies ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

The Past ◽

The World ◽

The Usa ◽

Insulin Dependent ◽

Therapeutic Measures

Insulin-dependent diabetes mellitus (T1DM) is one of the most important problems of our time. This disease plays a significant role in the structure of chronic childhood pathology, leads to severe complications that invalidate a person, and significantly increases mortality at a young age. The study of the incidence of T1DM (the number of new cases of T1DM in a certain population within 1 year) allows you to get answers to a number of questions on its etiology and pathogenesis, to solve the problems of the need to allocate material resources for the organization of preventive and therapeutic measures. Information on the incidence of T1DM in the world applies in most cases to people under the age of 15 years, data for the age group up to 1820 years of age are less common. Epidemiological studies in various countries show an increase in the incidence of T1DM in children. This is shown by the example of Norway, the USA, Finland, Denmark from the 20s of our century, England - from the 50s and other countries over the past 20 years. It is possible to reliably distinguish a true increase in the incidence from an improvement in the detection of diabetes only on the basis of standardized epidemiological studies for certain periods of time. Many countries have compiled national childhood diabetes registries. Thus, in a number of countries standardized information on sex and age was obtained on the incidence of children with T1DM for at least 10 years, divided into 5-year periods. According to these data, the incidence rate has increased in the vast majority of countries over the past 10-20 years. It is noteworthy that the change, namely, an increase in the incidence of type 1 diabetes mellitus in children, is uneven. In some regions of the world, this indicator remained virtually unchanged over fairly long periods of time.

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