scholarly journals Long-Term Continuous-Flow Biventricular Support in a 63-Year-Old Woman

2018 ◽  
Vol 45 (2) ◽  
pp. 110-112
Author(s):  
Andrew C.W. Baldwin ◽  
William E. Cohn ◽  
Jeffrey A. Morgan ◽  
O.H. Frazier
Keyword(s):  
Continuous Flow ◽  
Older Patients ◽  
Mechanical Circulatory Support ◽  
Circulatory Support ◽  
Orthotopic Heart Transplantation ◽  
Nonischemic Cardiomyopathy ◽  
Bridge To Transplantation ◽  
Similar Patient ◽  
Ventricular Support

We describe the successful use of long-term biventricular continuous-flow mechanical circulatory support as a bridge to transplantation in a small-framed 63-year-old woman with long-standing nonischemic cardiomyopathy. After placement of a left-sided HeartWare HVAD, persistent right-sided heart failure necessitated implantation of a second HeartWare device for long-term right ventricular support. After 262 days, the patient underwent successful orthotopic heart transplantation and was discharged from the hospital. This report indicates the feasibility of biventricular device support in older patients of relatively small stature, and our results may encourage others to consider this therapy in similar patient populations.

Mechanical Circulatory Support: Heart Failure Therapy “in Motion”

2016 ◽  
Vol 11 (5) ◽  
pp. 305-314 ◽  
Author(s):  
Stephan M. Ensminger ◽  
Gino Gerosa ◽  
Jan F. Gummert ◽  
Volkmar Falk
Keyword(s):  
Heart Failure ◽  
Adverse Events ◽  
Continuous Flow ◽  
Mechanical Circulatory Support ◽  
First Generation ◽  
Ventricular Assist Devices ◽  
Circulatory Support ◽  
Destination Therapy ◽  
Flow Devices

Because the first generation of pulsatile-flow devices was primarily used to bridge the sickest patients to transplantation (bridge-to-transplant therapy), the current generation of continuous-flow ventricular assist devices qualifies for destination therapy for patients with advanced heart failure who are ineligible for transplantation. The first-generation devices were associated with frequent adverse events, limited mechanical durability, and patient discomfort due device size. In contrast, second-generation continuous-flow devices are smaller, more quiet, and durable, thus resulting in less complications and significantly improved survival rates. Heart transplantation remains an option for a limited number of patients only, and this fact has also triggered the discussion about the optimal timing for device implantation. The increasing use of continuous-flow devices has resulted in new challenges, such as adverse events during long-term support, and high hospital readmission rates. In addition, there are a number of device-related complications including mechanical problems such as device thrombosis, percutaneous driveline damage, as well as conditions such as hemolysis, infection, and cerebrovascular accidents. This review provides an overview of the evolution of mechanical circulatory support systems from bridge to transplantation to destination therapy including technological advances and clinical improvements in long-term patient survival and quality of life. In addition, recent changes in device implant strategies and current trials are reviewed and discussed. A brief glimpse into the future of mechanical circulatory support therapy will summarize the innovations that may soon enter clinical practice.

scholarly journals A review of implantable pulsatile blood pumps: Engineering perspectives

2020 ◽  
Vol 43 (9) ◽  
pp. 559-569
Author(s):  
Tingting Wu ◽  
Ashraf W Khir ◽  
Maximilian Kütting ◽  
Xinli Du ◽  
Hao Lin ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Mechanical Circulatory Support ◽  
Circulatory Support ◽  
Blood Pumps ◽  
Support Device ◽  
Mechanical Circulatory Support Devices ◽  
Mechanical Circulatory Support Device ◽  
Support Devices ◽  
Circulatory Support Device

It has been reported that long-term use of continuous-flow mechanical circulatory support devices (CF-MCSDs) may induce complications associated with diminished pulsatility. Pulsatile-flow mechanical circulatory support devices (PF-MCSDs) have the potential of overcoming these shortcomings with the advance of technology. In order to promote in-depth understanding of PF-MCSD technology and thus encourage future mechanical circulatory support device innovations, engineering perspectives of PF-MCSD systems, including mechanical designs, drive mechanisms, working principles, and implantation strategies, are reviewed in this article. Some emerging designs of PF-MCSDs are introduced, and possible elements for next-generation PF-MCSDs are identified.

Long-term survival on mechanical circulatory support

2008 ◽  
Vol 7 ◽  
pp. 173-173
Author(s):  
A GKOUZIOUTA ◽  
E LEONTIADIS ◽  
S ADAMOPOULOS ◽  
A MANGINAS ◽  
G KARAVOLIAS ◽  
...  
Keyword(s):  
Mechanical Circulatory Support ◽  
Circulatory Support ◽  
Term Survival ◽  
Long Term Survival

Bridge to transplantation with mechanical circulatory support extended beyond one year

2005 ◽  
Vol 53 (S 3) ◽  
Author(s):  
M Jurmann ◽  
Y Weng ◽  
T Drews ◽  
M Pasic ◽  
H Lehmkuhl ◽  
...  
Keyword(s):  
Mechanical Circulatory Support ◽  
Circulatory Support ◽  
Bridge To Transplantation ◽  
One Year
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