scholarly journals Role of fine needle aspiration cytology (FNAC) in diagnosing Pancreatic lesions in a tertiary care institution

2021 ◽  
Vol 8 (6) ◽  
pp. 70-76
Author(s):  
Sonia Jain ◽  
Pavneet Kaur Selhi ◽  
Harpreet Kaur ◽  
Ajay Gupta ◽  
Siddharth Prakash
Keyword(s):  
Pancreatic Cancer ◽  
Tertiary Care ◽  
Age Distribution ◽  
Needle Aspiration ◽  
Care Hospital ◽  
Cancer Risk Factors ◽  
Male Predominance ◽  
Pancreatic Masses ◽  
Tertiary Care Institution ◽  
Needle Aspiration Cytology

OBJECTIVE- FNAC is an accurate and rapid technique for diagnosing pancreatic masses. Pancreatic carcinoma represents the seventh leading cause of cancer death in the world, responsible for more than 300,000 deaths per year.[1] Worldwide, both the incidence and death rates of pancreatic cancer are increasing. The aim of this study was early diagnosis of these lesions and to evaluate its burden and study the global, regional, and national patterns. These would further aid in policy making , better resource allocation for controlling pancreatic cancer risk factors and formulating more effective treatments.[2] METHODS- This was a retrospective observational study performed at a tertiary care hospital over a period of one and a half year. A total of 86 patients with pancreatic lesions were subjected to image guided FNA . 35 of these patients underwent diagnostic histopathology in addition to FNA. RESULTS- The 86 cases analyzed were in the age group of 61-70 years with mean age distribution of 57.34 years. Male predominance was seen with M:F ratio of 2.18:1. Head was the most common area to be aspirated followed by tail and least number of lesions were in body of pancreas. Maximum cases were found to be malignant (55) in etiology. Only 2 were non diagnostic because one of them had insufficient cellularity and other had necrosis mainly on histopathology. Adenocarcinoma was the most common malignancy found followed by one case each of lymphoma and solid pseudo papillary neoplasm of pancreas. Histo pathological correlation was obtained in 91.42% cases proving that FNA is a very useful tool in early diagnosing pancreatic lesions.

scholarly journals Diagnostic Accuracy of the Bethesda System of Reporting Thyroid Cytopathology in the Evaluation of Thyroid Nodule in a Tertiary Care Hospital of Kolkata

2021 ◽  
Vol 8 (05) ◽  
pp. 241-245
Author(s):  
Sweta Verma ◽  
Mita Saha Dutta Chowdhury ◽  
Souradeep Ray ◽  
Ruma Guha
Keyword(s):  
Diagnostic Accuracy ◽  
Thyroid Nodule ◽  
Thyroid Nodules ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Care Hospital ◽  
Risk Of Malignancy ◽  
Needle Aspiration Cytology ◽  
Thyroid Cytopathology ◽  
The Bethesda System

BACKGROUND Thyroid cancer has the most rapidly increasing incidence of all major cancers in India. The overall prevalence of thyroid malignancy is approximately 1 - 5 % of all cancers in women and less than 2 % in men. Thyroid nodules are a common clinical finding and have a reported prevalence of 4 – 7 % in the general population. The vast majority of these nodules are non-neoplastic or benign and the risk of malignancy varies from 5 to 10 %. Fine needle aspiration cytology (FNAC) is an efficient and reliable means for the evaluation of thyroid nodules. A key challenge for clinicians is to choose which thyroid nodule is to be investigated further and treated. Early detection and treatment of malignant thyroid nodules is associated with excellent outcomes. The aim of our study is to compare and correlate between fine needle aspiration cytology and histopathology of resected specimen and to determine the diagnostic accuracy of TBSRTC (The Bethesda System for Reporting Thyroid Cytopathology) in thyroid nodule. METHODS This is a cross sectional validation study conducted in a tertiary care hospital (R.G. Kar Medical College) of Kolkata to find the sensitivity, specificity and diagnostic accuracy of TBSRTC in evaluation of thyroid nodule. RESULTS We have observed that TBSRTC is highly sensitive and specific in stratifying the malignancy risk of thyroid nodule. CONCLUSIONS It aids the clinician to choose the thyroid nodules which require further evaluation and intervention. It also guides the clinician to decide the operability of thyroid nodule. TBSRTC is highly accurate and is highly specific in stratifying the risk of malignancy of thyroid nodule. KEYWORDS TBSRTC, FNAC, Thyroid Nodules, Thyroid Cancer

scholarly journals “COMPARATIVE STUDY OF FNAC, USG, US-FNAC, AND HPE IN DIAGNOSIS OF NECK SWELLINGS”

2021 ◽  
Vol Volume 9 (upjohns/volume9/Issue2) ◽  
pp. 15-21
Author(s):  
Sachin Jain
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Care Hospital ◽  
Neck Swelling ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

ABSTRACT Aims: This prospective study was carried out to compare findings of the four procedures namely FNAC (fine-needle aspiration cytology), USG (ultrasonography), US-FNAC (Ultrasound-guided fine-needle aspiration cytology), and HPE (histopathological examination). MATERIAL AND METHODS Total 80 cases of different neck swellings were selected from ENT OPD at tertiary care hospital Prayagraj Uttar Pradesh. All cases underwent the preoperative procedure of FNAC,USG, US-FNAC and postoperative HPE for diagnosing the neck swelling. The results of FNAC, USG, US-FNAC w e r e c o m p a r e d a n d c o r r e l a t e d w i t h histopathology findings and conclusions drawn after statistical analysis. RESULTS More than half (56.25%) of neck swellings were of thyroid swellings. It was observed that sensitivity, specificity, PPV, NPV, accuracy of FNAC of all neck swellings were 85.71%, 91.78% ,50%, 98.53% ,91.25% respectively. Sensitivity ,specificity, PPV ,NPV , accuracy of all neck swellings of USG were 71.43%, 98.63%, 83.33% , 97.26% 96.25 respectively. Sensitivity ,specificity, PPV ,NPV , accuracy of all neck swellings of US-FNAC were 85.71% ,97.26% ,75% , 98.61%, 96.25 respectively. CONCLUSION The combined use of USG and FNAC give more accuracy for proper diagnosis of neck swelling than FNAC alone. The most accurate diagnosis of

scholarly journals The spectrum of palpable breast lesions- A cytopathological study of 1193 cases

2021 ◽  
Vol 7 (3) ◽  
pp. 144-149
Author(s):  
Manasa GC ◽  
◽  
Sneha SP ◽  
Adicherla Govardhan ◽  
◽  
...  
Keyword(s):  
Ductal Carcinoma ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Female Breast Cancer ◽  
Care Hospital ◽  
Age Group ◽  
Breast Lump ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

Introduction- The vast majority of the lesions that occur in the breast are benign. Much concern isgiven to malignant lesions of the breast because female breast cancer has now surpassed lungcancer as the leading cause of global cancer incidence in 2020. Fine needle aspiration cytology(FNAC) has good sensitivity, specificity and accuracy in the diagnosis of both neoplastic and non-neoplastic breast lump thereby assisting in early diagnosis and further management. The currentstudy was done to study the incidence and the different cytomorphological patterns of palpablebreast lumps by FNAC and consequently compare the results with studies in the literature.Materials and methods- This is a retrospective study conducted from January 2018 to December2020 in a tertiary care hospital. The three-year data is obtained from the records maintained in theFNA clinic. The patients were counselled before the procedure and informed consent was taken.Results- A total of 1193 breast lump cases were analysed in this 3-year study, there were 19 malepatients all of them presented with gynaecomastia and 1177 female patients. The patient’s agegroup ranged from 12 to 86 years. The commonest age group with the lesions 31-40 yearscomprising 326 cases (27.32%) followed 21-30 years age group in the second place with 307 cases(25.7%). Conclusion- In this study the most common benign neoplastic and malignant neoplasticbreast lumps are fibroadenoma and infiltrating ductal carcinoma respectively. Fibrocystic disease ofthe breast is the most common non-neoplastic breast lump.

scholarly journals Tuberculous Mastitis: Experience of Five Cases at a Tertiary Care Hospital

2016 ◽  
Vol 4 (2) ◽  
pp. 67-70
Author(s):  
Md Hasanuzzaman ◽  
Md Johirul Islam ◽  
AZM Mostaque Hossain ◽  
Mohammad Zillur Rahman ◽  
Md Ashraf Ul Haque ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Surgical Oncology ◽  
Needle Aspiration ◽  
Care Hospital ◽  
Aspiration Cytology ◽  
Antitubercular Drugs ◽  
Granulomatous Lesions ◽  
Needle Aspiration Cytology ◽  
Breast Lumps ◽  
High Index Of Suspicion

Background: Tuberculous Mastitis (TM) is a rare form of tuberculosis, even in countries where the burden of tuberculosis is high. It may mimic other systemic illness, even carcinoma breast, a condition with which it may coexist.Objective: To disseminate the message to the concerned expertise that it can present a diagnostic problem on radiological and microbiological investigations, and thus a high index of suspicion is needed.Materials and method: This observational study was carried out in the department of Surgical Oncology of National Institute of Cancer Research & Hospital (NICRH), Dhaka, Bangladesh from January 2010 to December 2015. During the study period only five cases of TM were identified and all were included in the analysis purposively.Results: Mean(±SD) age of the patients was 27.2(±16.22) years. AFB in pus was found in one patient. Fine Needle Aspiration Cytology (FNAC) was done in four AFB negative patients and granulomatous lesions were found in each case. Histopathological examinations of two resected breast lumps also showed granulomatous lesions consistent with tuberculosis. Breast ultrasound showed multilocular abscess with ill-defined lump in two cases, solitary lump in two patients and cystic lesion in one patient. Axillary lymphadenopathy was found in one patient with solitary lump. Repeated image guided aspiration of the abscess was performed in 3 cases. Two patients underwent lumpectomy operation. All five patients were given anti-TB chemotherapy for 6 months. All of them recovered fully after completion of Category I treatment.Conclusion: Though it is a great mimicker with proper evaluation the disease is curable with antitubercular drugs, and in some cases surgery is required.Delta Med Col J. Jul 2016 4(2): 67-70

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