scholarly journals The spectrum of palpable breast lesions- A cytopathological study of 1193 cases

2021 ◽  
Vol 7 (3) ◽  
pp. 144-149
Author(s):  
Manasa GC ◽  
◽  
Sneha SP ◽  
Adicherla Govardhan ◽  
◽  
...  
Keyword(s):  
Ductal Carcinoma ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Female Breast Cancer ◽  
Care Hospital ◽  
Age Group ◽  
Breast Lump ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

Introduction- The vast majority of the lesions that occur in the breast are benign. Much concern isgiven to malignant lesions of the breast because female breast cancer has now surpassed lungcancer as the leading cause of global cancer incidence in 2020. Fine needle aspiration cytology(FNAC) has good sensitivity, specificity and accuracy in the diagnosis of both neoplastic and non-neoplastic breast lump thereby assisting in early diagnosis and further management. The currentstudy was done to study the incidence and the different cytomorphological patterns of palpablebreast lumps by FNAC and consequently compare the results with studies in the literature.Materials and methods- This is a retrospective study conducted from January 2018 to December2020 in a tertiary care hospital. The three-year data is obtained from the records maintained in theFNA clinic. The patients were counselled before the procedure and informed consent was taken.Results- A total of 1193 breast lump cases were analysed in this 3-year study, there were 19 malepatients all of them presented with gynaecomastia and 1177 female patients. The patient’s agegroup ranged from 12 to 86 years. The commonest age group with the lesions 31-40 yearscomprising 326 cases (27.32%) followed 21-30 years age group in the second place with 307 cases(25.7%). Conclusion- In this study the most common benign neoplastic and malignant neoplasticbreast lumps are fibroadenoma and infiltrating ductal carcinoma respectively. Fibrocystic disease ofthe breast is the most common non-neoplastic breast lump.

scholarly journals Study of clinical, imaging and pathological assessment of breast lumps: an observational study

2020 ◽  
Vol 7 (5) ◽  
pp. 1452
Author(s):  
Sumedha Laul ◽  
Divish Saxena ◽  
Nitin Wasnik
Keyword(s):  
Final Diagnosis ◽  
Needle Aspiration ◽  
Age Group ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Malignant Breast ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: A palpable lump in a woman’s breast could be benign or malignant and it requires prompt evaluation to confirm or exclude cancer. This study aims to establish the correlation between clinical and radiological parameters for provisional diagnosis of breast lumps and the role of histopathology for final diagnosis of these breast lumps.Methods: Total 275 female patients with palpable breast lumps were included in the study, where a detailed history was recorded and clinical examination was done. All patients underwent ultrasonography of the breast along with fine needle aspiration cytology or histopathology, wherever indicated.Results: Benign breast lumps were found more commonly in 18-30 years of age group whereas malignant breast lumps were seen more commonly in the 41-60 years age group and the incidence increased with age. Fixity to skin was present in 5.1% and fixity to chest wall was present in 5.8% respectively, and all of these cases turned out to be malignant.Conclusions: Attributing factors for suspicion of malignant lumps are advanced age, fixity to surrounding structures, presence of ulceration and peau’d orange breast skin appearance. Although for confirmation of malignancy from a suspected breast lump requires either cytology or histopathology of the excised specimen.

scholarly journals “COMPARATIVE STUDY OF FNAC, USG, US-FNAC, AND HPE IN DIAGNOSIS OF NECK SWELLINGS”

2021 ◽  
Vol Volume 9 (upjohns/volume9/Issue2) ◽  
pp. 15-21
Author(s):  
Sachin Jain
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Care Hospital ◽  
Neck Swelling ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

ABSTRACT Aims: This prospective study was carried out to compare findings of the four procedures namely FNAC (fine-needle aspiration cytology), USG (ultrasonography), US-FNAC (Ultrasound-guided fine-needle aspiration cytology), and HPE (histopathological examination). MATERIAL AND METHODS Total 80 cases of different neck swellings were selected from ENT OPD at tertiary care hospital Prayagraj Uttar Pradesh. All cases underwent the preoperative procedure of FNAC,USG, US-FNAC and postoperative HPE for diagnosing the neck swelling. The results of FNAC, USG, US-FNAC w e r e c o m p a r e d a n d c o r r e l a t e d w i t h histopathology findings and conclusions drawn after statistical analysis. RESULTS More than half (56.25%) of neck swellings were of thyroid swellings. It was observed that sensitivity, specificity, PPV, NPV, accuracy of FNAC of all neck swellings were 85.71%, 91.78% ,50%, 98.53% ,91.25% respectively. Sensitivity ,specificity, PPV ,NPV , accuracy of all neck swellings of USG were 71.43%, 98.63%, 83.33% , 97.26% 96.25 respectively. Sensitivity ,specificity, PPV ,NPV , accuracy of all neck swellings of US-FNAC were 85.71% ,97.26% ,75% , 98.61%, 96.25 respectively. CONCLUSION The combined use of USG and FNAC give more accuracy for proper diagnosis of neck swelling than FNAC alone. The most accurate diagnosis of

scholarly journals Histopathological Study of Malignant Neoplasm of Breast of Different Age and Sex Groups In a Tertiary Care Hospital

2018 ◽  
Vol 5 (2) ◽  
pp. 42-44
Author(s):  
Nazmun Nahar ◽  
Mohammed Iqbal ◽  
Kazi Md Shahidur Rahman ◽  
Md Abdullah Yusuf ◽  
Shahed Iqbal ◽  
...  
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Breast Neoplasm ◽  
Ductal Carcinoma ◽  
Tertiary Care ◽  
Malignant Neoplasm ◽  
Care Hospital ◽  
Age Group ◽  
Breast Lump ◽  
Malignant Breast ◽  
Age And Sex

Background: Various types of female breast cancer associated with rapidly increasing age incidence. Objective: The purpose of the present study was to find out the frequency of different types of malignant neoplasm of breast in different age and sex.Methodology: This cross-sectional study was carried out at the Department of Pathology, Chittagong Medical College, Chittagong, Bangladesh from May 2005 to June 2006. Patients presented with breast lump of different age and sex were subjected to this study. Details gross examination was done followed by H & E staining for histopathological study.Result: A total number of 48 samples were selected after fulfilling the inclusion and exclusion criteria. This present study conducted in 27 specimens out of 48 breast lump. Among these benign and malignant were 21 and 27, respectively. Majority of the malignancy found in age group 41-50 years. Histopathologically Invasive ductal carcinoma was common 81.5%.There was significant association between different age group and type of neoplasm. In relation to sex malignant breast neoplasm was more common in female.Conclusion: In conclusion invasive ductal carcinoma was the commonest lesion of breast. In relation to sex malignant breast neoplasm was more common in female.Journal of Current and Advance Medical Research 2018;5(2):42-44

scholarly journals Cytological Study of Palpable Breast Lump Presenting in Eastern Nepal

2017 ◽  
Vol 1 (1) ◽  
pp. 27-32
Author(s):  
M. Singh ◽  
S.U. Kafle ◽  
K.K. Jha
Keyword(s):  
Benign Lesion ◽  
Significant Proportion ◽  
Needle Aspiration ◽  
Age Group ◽  
Breast Lump ◽  
Pathologic Assessment ◽  
Malignant Lesions ◽  
The Common ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

Introduction Breast lump constitute significant proportion of surgical cases. It is necessary to distinguish between benign and malignant lesions for definite treatment. Fine needle aspiration cytology (FNAC) is widely adopted for the pathologic assessment because of its accuracy and ease of use.Objective The present study was done to find out the frequency of various patterns of breast lesion on FNAC and the common age - group in which the lesions occurs.Methodology This is a four years retrospective study carried out from December 2011 to January 2016. The 553 patients who presented with palpable breast lump, and have underwent FNAC irrespective of age and sex were included in the study. All the datas were collected from the patients record form. FNAC findings were correlated with the data from histopathology records to determine the sensitivity and specificity of FNAC.Results The majority of the patients were female and majority of lump was benign. Fibroadenoma was the most common lesion accounting for 32.18 % of all lesions and most commonly occurring in age group between 21 -30 years. Fibrocystic disease was second common benign lesion accounting for 30.56 also commonly accounting in the age group 21- 30 years. Carcinoma breast was seen in 5.42 % of cases (30/553) occurring most commonly in the female patients above 30 years of age. Most common age group for gynaecomastia in male breast was 11 – 20 years.Conclusion FNAC is a rapid and safe method for diagnosing palpable breast lump into benign and malignant categorizes and thus avoiding unnecessary surgery.Birat Journal of Health Sciences 2016 1(1): 27-32

scholarly journals Cytopathological and histopathological evaluation of neck mass in a tertiary care hospital

2021 ◽  
Vol 7 (9) ◽  
pp. 1432
Author(s):  
Yaladahalli G. Lokesh ◽  
Dudda Ravi ◽  
Hodeyala J. Srikanth
Keyword(s):  
Diagnostic Tool ◽  
Predictive Value ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Neck Mass ◽  
Care Hospital ◽  
Neck Masses ◽  
Cytological Features ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

<p class="abstract"><strong>Background:</strong> Patients with neck swellings are commonly seen in ENT outpatient and leads to dilemma in diagnosis. To prevent unnecessary investigations and surgery a simple and sensitive diagnostic tool is needed. Fine needle aspiration cytology (FNAC) is a simple and sensitive diagnostic tool that can provide results in minutes.</p><p class="abstract"><strong>Methods:</strong> This prospective study was done at the department of ENT, Mandya institute of medical sciences, Mandya, Karnataka, India from November 2017 to April 2019 including 100 cases of neck masses in patients aged above 18 years. FNAC was done for all neck masses and then these cases were subjected for biopsy. The cytological features was then reviewed with corresponding histopathology features.</p><p class="abstract"><strong>Results:</strong> Out of the 100 neck masses under study 67 (67%) were males and 33 (33%) were females with male:female ratio (1:2.03). Thyroid aspirations (43%) were most common followed by lymph node (24%), salivary gland aspirations (18%), congenital swellings (8%) and others (7%). Out of the 100 cases 26% were neoplastic and 74% were non-neoplastic. Histopathological correlations were available in all the 100 cases with sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 84.2%, 98.65%, 95.65% and 94.81% respectively. FNAC was in correlation with histopathology in 86% of cases and found to be statistically significant.</p><p class="abstract"><strong>Conclusions:</strong> FNAC is safe, simple and minimally invasive first line investigation of choice for the patients presenting with palpable neck masses and can provide results rapidly and but histopathology remains the gold standard.</p>

scholarly journals Fine Needle Aspiration Cytology of Palpable Breast Lumps - Their Cytological Spectrum and Histopathological Correlation

KYAMC Journal ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. 780-786
Author(s):  
Shaheen Akter ◽  
Md Jahidul Islam ◽  
Md Shariful Haque
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Histopathological Correlation ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: With the advent of fine needle aspiration cytology (FNAC), the approach to diagnosis and management of breast lumps has been revolutionized and it has high sensitivity and specificity.Aim: In this study we analyze the spectrum of FNAC diagnoses in breast lumps and compare the diagnostic accuracy of fine FNAC in differentiating the benign and malignant lesions of breast lumps with histopathological correlation.Materials & Methods: Two years prospective study was conducted in our institution and in that 490 aspirations, including 6 bilateral were performed. Suppurative and inflammatory lesions were excluded from the total aspirates. The cytological diagnosis was classified into 3 groups benign, suspicious and malignant. After this reporting all the available 94 cases were later subjected to mastectomy or open/excision biopsy and followed-up by histopathological confirmation. Later diagnostic accuracy of cytology reporting was compared with that of histopathology.Results: A total of 490 FNAC cases were reported including 373 as benign, 4 as suspicious for carcinoma and 113 as carcinoma. Majorities were premenopausal females and commonest age group was 31-40 years. Among them only 94 cases were followed-up by histopathologic confirmation. In histopathological correlation study, we had accuracy rate of 100% for benign lesion and 92.10% for malignant lesion with false negative rate of 7.90% and false positive rate of zero with fine needle aspiration cytology in the diagnosis of palpable breast lump. The overall sensitivity of fine needle aspiration in diagnosing the palpable breast lump is 92.10%, specificity is 100%, positive predictive value is 100% and negative predictive value is 94.91%.Conclusion: FNAC in experienced hands is a very useful tool with very high specificity and rare false positive result. Sensitivity can be further improved with clinical and imaging correlation.KYAMC Journal Vol. 7, No.-2, Jan 2017, Page 780-786

scholarly journals Diagnostic Accuracy of the Bethesda System of Reporting Thyroid Cytopathology in the Evaluation of Thyroid Nodule in a Tertiary Care Hospital of Kolkata

2021 ◽  
Vol 8 (05) ◽  
pp. 241-245
Author(s):  
Sweta Verma ◽  
Mita Saha Dutta Chowdhury ◽  
Souradeep Ray ◽  
Ruma Guha
Keyword(s):  
Diagnostic Accuracy ◽  
Thyroid Nodule ◽  
Thyroid Nodules ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Care Hospital ◽  
Risk Of Malignancy ◽  
Needle Aspiration Cytology ◽  
Thyroid Cytopathology ◽  
The Bethesda System

BACKGROUND Thyroid cancer has the most rapidly increasing incidence of all major cancers in India. The overall prevalence of thyroid malignancy is approximately 1 - 5 % of all cancers in women and less than 2 % in men. Thyroid nodules are a common clinical finding and have a reported prevalence of 4 – 7 % in the general population. The vast majority of these nodules are non-neoplastic or benign and the risk of malignancy varies from 5 to 10 %. Fine needle aspiration cytology (FNAC) is an efficient and reliable means for the evaluation of thyroid nodules. A key challenge for clinicians is to choose which thyroid nodule is to be investigated further and treated. Early detection and treatment of malignant thyroid nodules is associated with excellent outcomes. The aim of our study is to compare and correlate between fine needle aspiration cytology and histopathology of resected specimen and to determine the diagnostic accuracy of TBSRTC (The Bethesda System for Reporting Thyroid Cytopathology) in thyroid nodule. METHODS This is a cross sectional validation study conducted in a tertiary care hospital (R.G. Kar Medical College) of Kolkata to find the sensitivity, specificity and diagnostic accuracy of TBSRTC in evaluation of thyroid nodule. RESULTS We have observed that TBSRTC is highly sensitive and specific in stratifying the malignancy risk of thyroid nodule. CONCLUSIONS It aids the clinician to choose the thyroid nodules which require further evaluation and intervention. It also guides the clinician to decide the operability of thyroid nodule. TBSRTC is highly accurate and is highly specific in stratifying the risk of malignancy of thyroid nodule. KEYWORDS TBSRTC, FNAC, Thyroid Nodules, Thyroid Cancer

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