scholarly journals Immune Reconstitution Inflammatory Syndrome Mimicking Progressive Multifocal Leucoencephalopathy in a Multiple Sclerosis Patient Treated With Natalizumab: A Case Report and Review of the Literature

2015 ◽  
Vol 7 (1) ◽  
pp. 65-68 ◽  
Author(s):  
Maria-Eleptheria Evangelopoulos ◽  
Vasilios Koutoulidis ◽  
Kostas Kilidireas ◽  
Dimitrios-Stergios Evangelopoulos ◽  
Georgios Nakas ◽  
...  
2020 ◽  
Vol 37 (3-4) ◽  
pp. 97-99
Author(s):  
Vanice Rodrigues Poester ◽  
Lívia Silveira Munhoz ◽  
Rossana Patricia Basso ◽  
Beatriz Mendes Roca ◽  
Mariana Umpiérrez Vieira ◽  
...  

2020 ◽  
Vol 7 (7) ◽  
pp. 1187
Author(s):  
Nitish J. Sawan ◽  
Anita Basavaraj

Immune reconstitution inflammatory syndrome (IRIS) is defined as paradoxical worsening of a known condition or the appearance of a new condition after initiating antiretroviral therapy (ART) in HIV-infected patients. IRIS results from restored immunity to specific infectious or non-infectious antigens. Immune reconstitution following initiation of ART may lead to activation of an inflammatory response to detectable or latent JC virus (JCV) infection, an etiological agent of progressive multifocal leucoencephalopathy (PML). We present an interesting case of IRIS manifesting as PML in a newlydiagnosed HIV-infected patient started on ART.


Sign in / Sign up

Export Citation Format

Share Document