scholarly journals Highly differentiated follicular carcinoma arising from struma ovarii (strumosis) presenting as pseudo-Meigs syndrome with elevated CA125 level: a case report

Author(s):  
Olcay Kurtulan
2021 ◽  
Author(s):  
Aleksandra Asaturova ◽  
A. Magnaeva ◽  
A. Tregubova ◽  
V. Kometova ◽  
E. Karamurzin ◽  
...  

Abstract BackgroundStruma ovarii is a variant of monodermal teratoma, consisting of morphologically benign, atypical, or frankly malignant thyroid tissue. Morphologic features may or may not correlate with biologic behavior. Albeit this case report is not unique, ovarian tumor developed with peritoneal dissemination and bone metastasis, which is highly unlikely clinical complication. Additionally, we summarized previously cases of struma ovarii with an emphasis on correlation between morphological appearances, clinical course and providing treatment. Case presentationWe present the 38-year-old patient who was hospitalized for ovarian tumor. The diagnostic laparoscopy revealed lesions of peritoneum, sigmoid serosa and omentum and left ovarian mass. We diagnosed left ovarian mature teratoma without struma tissue and metastatic lesions with struma morphology which can be related to her history of left ovarian struma in 2016. Taking into account the metastatic lesions revealed in 2020, the tumor removed in 2016 was assessed as highly differentiated follicular carcinoma arising in struma ovarii. ConclusionsPrediction of biologic behavior of struma ovarii is still to be to diagnostic challenge, therefore multidisciplinary approach including clinical a n d laboratory findings, radiologic details and histopathological features is required. Providing additional data, the present case report contributes to expending the knowledge of these peculiar neoplasms.


Pathologica ◽  
2020 ◽  
Vol 112 (4) ◽  
pp. 224-228
Author(s):  
Faten Limaiem ◽  
Saadia Bouraoui

2019 ◽  
Vol 30 ◽  
pp. 100498 ◽  
Author(s):  
Takafumi Tsukada ◽  
Hiroshi Yoshida ◽  
Mitsuya Ishikawa ◽  
Yuka Asami ◽  
Kouya Shiraishi ◽  
...  

2019 ◽  
Vol 25 ◽  
pp. 310-311
Author(s):  
Safa Ibrahim ◽  
Geeti Sharma ◽  
Biswaraj Tharu ◽  
Manivel Eswaran

Author(s):  
Rosa Marquez-Pardo ◽  
Lourdes Garcia-Garcia-Doncel ◽  
Mgloria Baena-Nieto ◽  
Manuel Cayon-Blanco ◽  
Rosario Lopez-Velasco ◽  
...  

2007 ◽  
Vol 148 (48) ◽  
pp. 2285-2287 ◽  
Author(s):  
Gabriella Östör ◽  
Ildikó Tóth ◽  
Zsuzsanna Hrubyné Tóth ◽  
Sándor Bazsa

Az ovarialis strumák a petefészek-teratomák kevesebb mint 3%-át adják. Megjelenhet bennük a pajzsmirigy szinte minden betegsége, és előfordulhat malignitás is. A szerzők esetében egy 31 éves nő bal oldali petefészekcisztáját távolították el, amely az ovariumcarcinoma klinikai tüneteit mutatta, úgymint nagy hasi térfoglalás, ascites, emelkedett szérum-CA 125-szint. A szövettani diagnózis benignus struma ovarii volt. A posztoperatív pajzsmirigyműködés normális maradt.


2018 ◽  
Vol 64 (6) ◽  
pp. 708-715
Author(s):  
Natalya Severskaya ◽  
Andrey Rodichev ◽  
Aleksey Ilin ◽  
Dmitriy Semin ◽  
Pavel Isaev ◽  
...  

Struma ovarii is a rare variant of the mature ovarian teratoma composed of more than 50% thyroid tissue. Thyroid type carcinoma can occur in 5% of struma ovarii. Given the rarity of this pathology, as well as the different clinical course, approaches to the treatment of this disease are controversial. The proposed approaches to treatment vary from ovarian resection to total hysterectomy with bilateral salpingo-oophorectomy and adjuvant therapy. We present here 6 case reports of thyroid type carcinoma in struma ovarii and outcome of patients treated in our clinic. All patients had pelvic surgery of different extent, followed by thyroidectomy and radioiodine therapy. The incidence of metastasis is 67% (4/6), 2 - intraperitoneal metas-tases, 2 - bone metastases. Among patients with metastases, 2 have reached a complete response, one with a good response continues treatment, one had progression. The follow-up period is 1 to 15 years (median 4 years). One patient with follicular carcinoma died of progression 8 years after diagnosis. The remaining patients are alive.


2019 ◽  
Vol 54 (S1) ◽  
pp. 177-177
Author(s):  
L. Hovsepyan ◽  
S. Babloyan ◽  
A. Stepanyan ◽  
A. Khudaverdyan
Keyword(s):  

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