scholarly journals Diagnostic Study of a Synthetic Human Corticotropin-Releasing Hormone (hCRH) in Healthy Adult Males: Its Plasma Pharmacokinetics and the Effects on the Urinary Excretion of Steroid Hormones.

1993 ◽  
Vol 40 (5) ◽  
pp. 591-596 ◽  
Author(s):  
KOSHI TANAKA ◽  
MECUMI NAGATA ◽  
SACHIKO ITOH ◽  
MUNEHITO KUMAGAE ◽  
NAOKATA SHIMIZU

2001 ◽  
Vol 120 (5) ◽  
pp. A38-A39
Author(s):  
M WLK ◽  
C WANG ◽  
M VENICHAKI ◽  
S KUHNTMOORE ◽  
D ZHAO ◽  
...  


2011 ◽  
Vol 44 (06) ◽  
Author(s):  
K Lerche ◽  
M Willem ◽  
K Kleinknecht ◽  
C Romberg ◽  
U Konietzko ◽  
...  


2005 ◽  
Vol 38 (05) ◽  
Author(s):  
JM Deussing ◽  
C Kühne ◽  
M Panhuysen ◽  
B Pütz ◽  
J Breu ◽  
...  


1974 ◽  
Vol 75 (4) ◽  
pp. 647-652 ◽  
Author(s):  
G. Rannevik ◽  
J. Thorell

ABSTRACT Eight amenorrhoeic women were given 100 μg synthetic LRH (Hoechst) iv and im, respectively, at an interval of 2 weeks. Four of the women received the iv injection first and four the im injection. The urinary excretion of oestrogens and pregnanediol was low and unaltered throughout the test weeks. The effects of LRH were compared by serial measurements of the plasma LH and FSH during 8 h. The initial response of LH for up to 25 min and that of FSH for up to 60 min were equal whether LRH was given iv or im. The difference appeared later. Four hours after the injection the mean increase of LH to iv injection was 0.5 ng/ml (N. S.), while that to im injection was 1.9 ng/ml (P < 0.01). The corresponding values for FSH were 1.3 (P < 0.05) and 3.2 (P < 0.001). The effect of LRH administration im was thus found to be larger and more prolonged.



2020 ◽  
Author(s):  
Maria Filiponi ◽  
Sophia Gougoura ◽  
Christina Befani ◽  
Alexandra Bargiota ◽  
Panagiotis Liakos ◽  
...  


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