scholarly journals Suppression of free fatty acid receptor 1 expression in pancreatic β-cells in obese type 2 diabetic db/db mice: a potential role of pancreatic and duodenal homeobox factor 1

2019 ◽  
Vol 66 (1) ◽  
pp. 43-50 ◽  
Author(s):  
Kenji Kohara ◽  
Atsushi Obata ◽  
Tomohiko Kimura ◽  
Masashi Shimoda ◽  
Saeko Moriuchi ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Potential Role ◽  
Β Cells ◽  
Pancreatic Β Cells ◽  
Acid Receptor ◽  
Free Fatty Acid Receptor ◽  
Type 2 Diabetic

scholarly journals PPAR-γ Activation Increases Insulin Secretion through the Up-regulation of the Free Fatty Acid Receptor GPR40 in Pancreatic β-Cells

PLoS ONE ◽  
2013 ◽  
Vol 8 (1) ◽  
pp. e50128 ◽  
Author(s):  
Hyo-Sup Kim ◽  
You-Cheol Hwang ◽  
Seung-Hoi Koo ◽  
Kyong Soo Park ◽  
Myung-Shik Lee ◽  
...  
Keyword(s):  
Insulin Secretion ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Β Cells ◽  
Pancreatic Β Cells ◽  
Acid Receptor ◽  
Ppar Γ ◽  
Free Fatty Acid Receptor ◽  
Fatty Acid Receptor

scholarly journals EPA, not DHA, prevents fibrosis in pressure overload-induced heart failure: potential role of free fatty acid receptor 4

2015 ◽  
Vol 56 (12) ◽  
pp. 2297-2308 ◽  
Author(s):  
Julie A. Eclov ◽  
Qingwen Qian ◽  
Rebecca Redetzke ◽  
Quanhai Chen ◽  
Steven C. Wu ◽  
...  
Keyword(s):  
Heart Failure ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Potential Role ◽  
Pressure Overload ◽  
Acid Receptor ◽  
Free Fatty Acid Receptor ◽  
Fatty Acid Receptor

Discovery of a novel oxime ether scaffold as potent and orally bioavailable free fatty acid receptor 1 agonists

RSC Advances ◽  
2016 ◽  
Vol 6 (52) ◽  
pp. 46356-46365 ◽  
Author(s):  
Zheng Li ◽  
Jianyong Yang ◽  
Weijie Gu ◽  
Guoshen Cao ◽  
Xiaoting Fu ◽  
...  
Keyword(s):  
Insulin Secretion ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Β Cells ◽  
Pancreatic Β Cells ◽  
Acid Receptor ◽  
Free Fatty Acid Receptor ◽  
Orally Bioavailable ◽  
Glucose Stimulated Insulin Secretion ◽  
Fatty Acid Receptor

The free fatty acid receptor 1 (FFA1) plays a key role in amplifying glucose-stimulated insulin secretion in pancreatic β-cells.

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