scholarly journals Lung cancer as a second primary malignant tumor: prognostic values after surgical resection

2008 ◽  
Vol 7 (1) ◽  
pp. 50-53 ◽  
Author(s):  
J. Furak ◽  
I. Trojan ◽  
T. Szoke ◽  
A. Wolfard ◽  
E. Nagy ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Surgical Resection ◽  
Malignant Tumor ◽  
Second Primary ◽  
Primary Malignant Tumor

scholarly journals Routine follow-up after surgical treatment of lung cancer: is chest CT useful?

2021 ◽  
pp. e20210025 ◽  
Author(s):  
Juliana B F Morellato1 ◽  
Marcos D Guimarães2 ◽  
Maria L L Medeiros1 ◽  
Hélio A Carneiro1 ◽  
Alex D Oliveira2 ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Surgical Resection ◽  
Primary Lung Cancer ◽  
Cancer Recurrence ◽  
Chest Ct ◽  
Second Primary ◽  
Medical Visits ◽  
Asymptomatic Patients ◽  
Second Primary Lung Cancer

Objective: To report the experience of a routine follow-up program based on medical visits and chest CT. Methods: This was a retrospective study involving patients followed after complete surgical resection of non-small cell lung cancer between April of 2007 and December of 2015. The follow-up program consisted of clinical examination and chest CT. Each follow-up visit was classified as a routine or non-routine consultation, and patients were considered symptomatic or asymptomatic. The outcomes of the follow-up program were no evidence of cancer, recurrence, or second primary lung cancer. Results: The sample comprised 148 patients. The median time of follow-up was 40.1 months, and 74.3% of the patients underwent fewer chest CTs than those recommended in our follow-up program. Recurrence and second primary lung cancer were found in 17.6% and 11.5% of the patients, respectively. Recurrence was diagnosed in a routine medical consultation in 69.2% of the cases, 57.7% of the patients being asymptomatic. Second primary lung cancer was diagnosed in a routine medical appointment in 94.1% of the cases, 88.2% of the patients being asymptomatic. Of the 53 patients who presented with abnormalities on chest CT, 41 (77.3%) were diagnosed with cancer. Conclusion: Most of the cases of recurrence, especially those of second primary lung cancer, were confirmed by chest CT in asymptomatic patients, indicating the importance of a strict follow-up program that includes chest CTs after surgical resection of lung cancer.

scholarly journals A case of second primary lung cancer diagnosed by surgical resection at salvage setting

2018 ◽  
Vol 7 (3) ◽  
pp. 84-86
Author(s):  
Shozo Sakata ◽  
Tetsuya Mizuno ◽  
Hitoshi Dejima ◽  
Takaaki Arimura ◽  
Hiroaki Kuroda ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Surgical Resection ◽  
Primary Lung Cancer ◽  
Second Primary ◽  
Second Primary Lung Cancer

scholarly journals Outcomes after Contralateral Anatomic Surgical Resection in Multiple Lung Cancer

2020 ◽  
Author(s):  
Alex Fourdrain ◽  
Patrick Bagan ◽  
Olivier Georges ◽  
Sophie Lafitte ◽  
Florence De Dominicis ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Surgical Resection ◽  
Primary Lung Cancer ◽  
Extent Of Resection ◽  
Tumor Stage ◽  
Second Primary ◽  
Term Survival ◽  
Long Term Survival ◽  
Lung Cancers

Abstract Background Patients treated surgically for lung cancer may present synchronous or metachronous lung cancers. The aim of this study was to evaluate outcomes after a second contralateral anatomic surgical resection for lung cancer. Methods We performed a retrospective two-center study, based on a prospective indexed database. Included patients were treated surgically by bilateral anatomic surgical resection for a second primary lung cancer. We excluded nonanatomic resections, benign lesions, and ipsilateral second surgical resections. Results Between January 2011 and September 2018, 55 patients underwent contralateral anatomic surgical resections for lung cancer, mostly for metachronous cancers. The first surgical resection was a lobectomy in most cases (45 lobectomies: 81.8%, 9 segmentectomies: 16.4%, and 1 bilobectomy: 1.8%), and a video-assisted thoracic surgery (VATS) procedure was used in 23 cases (41.8%). The mean interval between the operations was 38 months, and lobectomy was less frequent for the second surgical resection (35 lobectomies: 63.6% and 20 segmentectomies: 36.4%), with VATS procedures performed in 41 cases (74.5%). Ninety-day mortality was 10.9% (n = 6), and 3-year survival was 77%. Risk factor analysis identified the number of resected segments during the second intervention or the total number of resected segments, extent of resection (lobectomy vs. segmentectomy), surgical approach (thoracotomy vs. VATS), tumor stage, and nodal involvement as potential prognostic factors for long-term survival. Conclusion A second contralateral anatomic surgical resection for multiple primary lung cancer is possible, with a higher early mortality rate, but acceptable long-term survival, and should be indicated for carefully selected patients.

scholarly journals Surgical Resection for a Second Primary Lung Cancer Originating Close to the Initial Surgical Margin for Lung Squamous Cell Carcinoma

2015 ◽  
Vol 2015 ◽  
pp. 1-5
Author(s):  
Seijiro Sato ◽  
Terumoto Koike ◽  
Takehisa Hashimoto ◽  
Masanori Tsuchida
Keyword(s):  
Lung Cancer ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Surgical Resection ◽  
Small Cell Carcinoma ◽  
Squamous Cell ◽  
Surgical Margin ◽  
Lung Squamous Cell Carcinoma ◽  
Small Cell ◽  
Second Primary

Few reports have described surgical resection for second primary lung cancers originating close to the initial surgical margin for lung cancer. A 64-year-old man had undergone left segmentectomy with lymph node dissection for small peripheral squamous cell lung cancer using video-assisted thoracic surgery, with pathology confirming a small tumor 12 mm in diameter identified about 3 cm from the surgical margin. Eighteen months after initial surgery, computed tomography revealed a 30 mm pulmonary nodule close to the initial surgical margin in the residual left upper lobe and the serum level of carcinoembryonic antigen was found to be increased. Local recurrence on the staple-line of the surgical margin was suspected, and completion left upper lobectomy was performed. Histological examination identified not only a squamous cell carcinoma component but also a small cell carcinoma component. The immunohistochemical staining pattern of the second tumor differed from that of the initial resected lung squamous cell carcinoma. The final pathological diagnosis was a second primary tumor with mixed small cell carcinoma and squamous cell carcinoma histology.

Hepatocyte ultrastructural alterations in perimetastatic areas

1996 ◽  
Vol 54 ◽  
pp. 768-769
Author(s):  
H. J. Finol ◽  
M. E. Correa ◽  
L.A. Sosa ◽  
A. Márquez ◽  
N.L. Díaz
Keyword(s):  
Malignant Tumor ◽  
Malignant Tumors ◽  
Surrounding Tissue ◽  
Ultrastructural Changes ◽  
Pancreas Carcinoma ◽  
Duct Carcinoma ◽  
Tissue Samples ◽  
Primary Malignant Tumor ◽  
Transmission Electron ◽  
Remote Sites

In classical oncological literature two mechanisms for tissue aggression in patients with cancer have been described. The first is the progressive invasion, infiltration and destruction of tissues surrounding primary malignant tumor or their metastases; the other includes alterations produced in remote sites that are not directly affected by any focus of disease, the so called paraneoplastic phenomenon. The non-invaded tissue which surrounds a primary malignant tumor or its metastases has been usually considered a normal tissue . In this work we describe the ultrastructural changes observed in hepatocytes located next to metastases from diverse malignant tumors.Hepatic biopsies were obtained surgically in patients with different malignant tumors which metatastized in liver. Biopsies included tumor mass, the zone of macroscopic contact between the tumor and the surrounding tissue, and the tissue adjacent to the tumor but outside the macroscopic area of infiltration. The patients (n = 5), 36–75 years old, presented different tumors including rhabdomyosarcoma, leiomyosarcoma, pancreas carcinoma, biliar duct carcinoma and colon carcinoma. Tissue samples were processed with routine techniques for transmission electron microscopy and observed in a Hitachi H-500 electron microscope.

Primary Malignant Tumor of the Fallopian Tube: CT and MR Features

2001 ◽  
Vol 45 (4) ◽  
pp. 393 ◽  
Author(s):  
Yu Ri Kahng ◽  
Jeong Kon Kim ◽  
Kyoung Sik Cho
Keyword(s):  
Fallopian Tube ◽  
Malignant Tumor ◽  
Primary Malignant Tumor
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