AbstractHelium effect on loss of uniform elongation after low-temperature neutron irradiation of the V-Ti-Cr-Si-Al-Y alloy was studied. Helium implantation to about 30 atomic ppm was carried out before neutron irradiation to 50 dpa at 406°C. The yield stress of the irradiated specimen with helium pre-implantation was slightly smaller than that of irradiated specimens without helium. The uniform elongation and the increase in yield stress of the irradiated specimens were not affected by helium pre-implantation at ambient temperature. It might be possible that the helium effect appears after lower temperature irradiation such as 300°C or lower, which corresponds to the temperature range where the loss of uniform elongation of the alloy is particularly pronounced.