Health related quality of life among postmenopausal woman with hormone responsive HER2− breast cancer in Indonesia

2021 ◽  
Vol 32 (4) ◽  
pp. 561-565
Author(s):  
Ria Etikasari ◽  
Tri Murti Andayani ◽  
Dwi Endarti ◽  
Kartika Widayati Taroeno-Hariadi
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Postmenopausal Women ◽  
Utility Score ◽  
Health State ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Anxiety Depression

Abstract Objectives Breast cancer (BC) in women could decrease health-related quality of life (HRQoL). HRQoL becomes important to be assessed to design a relevant treatment that could improve patient outcomes. Furthermore, assessing HRQoL by measuring health state utilities becomes pivotal for health economic evaluation. This study aimed to describe the HRQoL of postmenopausal women with hormone responsive (HR+) HER2− BC using the EQ5D5L instrument in Indonesia. Methods A cross-sectional study was conducted among 126 patients in Dr. Sardjito Hospital in Indonesia. The HRQoL was assessed by interviewing BC patients using the EQ5D5L questionnaire, and the utility index was calculated using the Indonesian value set. Information regarding clinical characteristic and socio-demographic were gained from patient medical records. One-way ANOVA and post-hoc Scheffe’s test was performed to compare the utility score within the health state. Results Of the 126 patients, a mean ± SD for the age of 59.2 ± 6.1 years. The major problems of patients were pain/discomfort (75.4%) followed by anxiety/depression (54.8%). The mean (SD) of EQ5D VAS was 76.64 (14.91). Mean (SD) of utility score was 0.87 (0.10), 0.77 (0.19) and 0.58 (0.44) for free metastasis (FM), locoregional metastasis (LM) and distant metastasis (DM), respectively. Poor QoL was observed at DM health state (p<0.05). Conclusions HRQoL of postmenopausal women with HR+ HER2− BC was low. The major reported problems were pain/discomfort and anxiety/depression.

scholarly journals Health-related quality of life among breast cancer patients compared to cancer survivors and age-matched women in the general population in Vietnam

2021 ◽  
Author(s):  
Tran Thu Ngan ◽  
Vu Quynh Mai ◽  
Hoang Van Minh ◽  
Michael Donnelly ◽  
Ciaran O’Neill
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
General Population ◽  
Online Survey ◽  
Well Being ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Anxiety Depression

Abstract Purpose This study compared the health-related quality of life (HRQoL) of breast cancer (BC) patients, survivors, and age-matched women from the general population in Vietnam to address the paucity of HRQoL research and contribute to the robust assessment of BC screening and care in Vietnam. Methods The standardised EQ-5D-5L instrument was incorporated in an online survey and a hospital-based face-to-face survey, and together with data from the Vietnam EQ-5D-5L norms study. χ2 tests assessed EQ-5D health profile associations and a Tobit regression model investigated the association between overall health status (EQ-VAS/utility scores) and sociodemographic and clinical characteristics. Results A total of 309 participants (107 patients undergoing treatment and 202 survivors who had completed treatment) provided usable responses. The dimensions that affected mostly the HRQoL of women with BC were pain/discomfort and anxiety/depression. Current patients and survivors differed significantly regarding HRQoL dimensions of mobility, self-care, usual activities, and anxiety/depression. Their health utilities were 0.74 and 0.84, respectively, compared with 0.91 for age-matched Vietnamese women in the general population (p < 0.001). Treatment status (survivor vs patient), younger age, higher monthly household income, and higher education levels were associated with higher health utility. Conclusions The results point to unmet needs in mental health support and well-being and for attention to be given to the development of a biopsychosocial system of cancer diagnosis, treatment, and care. The results will also inform future assessments of the comparative value for money of interventions intended to impact on breast cancer in Vietnam.

Joint symptoms and health-related quality of life in postmenopausal women with breast cancer who completed 5 years of anastrozole

2015 ◽  
Vol 24 (2) ◽  
pp. 683-689 ◽  
Author(s):  
Hiroshi Yagata ◽  
Hiroshi Ohtsu ◽  
Yoshifumi Komoike ◽  
Shigehira Saji ◽  
Hiroyuki Takei ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Postmenopausal Women ◽  
Health Related Quality ◽  
Joint Symptoms ◽  
Related Quality ◽  
Health Related

scholarly journals Health-related quality of life among breast cancer patients compared to cancer survivors and age-matched women in the general population in Vietnam

2020 ◽  
Author(s):  
Tran Thu Ngan ◽  
Vu Quynh Mai ◽  
Hoang Van Minh ◽  
Michael Donnelly ◽  
Ciaran O’Neill
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
General Population ◽  
Online Survey ◽  
Well Being ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Anxiety Depression

Abstract Background This study compared the health-related quality of life (HRQoL) of BC patients, survivors, and age-matched women from the general population in Vietnam in order to address the paucity of HRQoL research and contribute to the robust assessment of breast cancer (BC) screening and care in Vietnam. Methods The standardised EQ-5D-5L instrument was incorporated in an online survey and a hospital-based face-to-face survey, and together with data from the Vietnam EQ-5D-5L norms Study. χ2 tests assessed EQ-5D health profile associations and a Tobit regression model investigated the association between overall health status (EQ-VAS/utility scores) and sociodemographic and clinical characteristics. Results A total of 309 participants (107 patients undergoing treatment and 202 survivors who had completed treatment) provided usable responses. The dimensions that affected most the HRQoL of women with BC were pain/discomfort and anxiety/depression. Current patients and survivors differed significantly regarding HRQoL dimensions of mobility, self-care, usual activities, and anxiety/depression. Their health utilities were 0.74 and 0.84, respectively, compared with 0.91 for age-matched Vietnamese women in the general population (p < 0.001). Treatment status (survivor vs patient), younger age, higher monthly household income, and higher education levels were associated with higher health utility. Conclusions The results point to unmet needs in mental health support and well-being and for attention to be given to the development of a biopsychosocial system of cancer diagnosis, treatment, and care. The results will also inform future assessments of the comparative value for money of interventions intended to impact on breast cancer in Vietnam.

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