Long Term Therapy with a Single Daily Subcutaneous Dose of Growth Hormone Releasing Hormone (1-29) in Prepubertal Growth Hormone Deficient Children

1994 ◽  
Vol 7 (4) ◽  
Author(s):  
R. Lanes ◽  
E. Carrillo ◽  
Venezuelan Collaborative Study Grou
Keyword(s):  
Growth Hormone ◽  
Term Therapy ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Subcutaneous Dose ◽  
Long Term Therapy

Restoration of gallbladder contractility after withdrawal of long-term octreotide therapy in acromegalic patients

1993 ◽  
Vol 129 (3) ◽  
pp. 207-212 ◽  
Author(s):  
Yi-Fan Shi ◽  
Xian-Feng Zhu ◽  
Alan G Harris ◽  
Jin-Xi Zhang ◽  
Jie-Ying Deng
Keyword(s):  
Growth Hormone ◽  
Growth Factor ◽  
Term Therapy ◽  
Serum Growth Hormone ◽  
Factor I ◽  
Gallbladder Contractility ◽  
Octreotide Therapy ◽  
Long Term Therapy ◽  
Growth Hormone Suppression

We sought to examine how the discontinuation of octreotide in long-term octreotide-treated acromegalic patients affects the well-documented side-effect of cholelithiasis. In 14 acromegalic patients, serum growth hormone levels, insulin-like growth factor I levels and percentage of relative gallbladder contractility were measured prior to and after the discontinuation of octreotide. Compared to pretreatment values, the basal growth hormone and 5-h growth hormone profiles were 36% and 24%, and 60% and 56% at the end of 1 and 2 weeks, respectively. Octreotide was found to be eliminated completely from the serum within 3 days after its withdrawal. In all of six patients who did not develop gallstones, the percentage relative gallbladder contractility normalized within 1 week. In eight patients who developed gallstones, four of them had restoration of normal contractility within 2 weeks. Our results show that upon withdrawal of octreotide, gallbladder contractility returns to normal while growth hormone suppression persists for a longer period of time. Therefore, discontinuation of octreotide therapy may allow for the clearance of stagnated bile and hence decrease the incidence of cholelithiasis in acromegalic patients receiving long-term therapy.

scholarly journals Hormonal and Volumetric Long Term Control of a Growth Hormone-Releasing Hormone-Producing Carcinoid Tumor

1999 ◽  
Vol 84 (9) ◽  
pp. 3162-3169 ◽  
Author(s):  
A. Van den Bruel ◽  
J. Fevery ◽  
J. Van Dorpe ◽  
L. Hofland ◽  
R. Bouillon
Keyword(s):  
Growth Hormone ◽  
Carcinoid Tumor ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone

Ectopic Growth Hormone-Releasing Hormone Secretion by a Neuroendocrine Tumor Causing Acromegaly: Long-Term Follow-Up Results

2009 ◽  
Vol 20 (2) ◽  
pp. 127-132 ◽  
Author(s):  
Neşe Colak Ozbey ◽  
Yersu Kapran ◽  
Alp Bozbora ◽  
Yeşim Erbil ◽  
Cemil Tascioglu ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Neuroendocrine Tumor ◽  
Hormone Secretion ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Long Term Follow Up

Myogenic expression of an injectable protease-resistant growth hormone–releasing hormone augments long-term growth in pigs

10.1038/70718 ◽  
1999 ◽  
Vol 17 (12) ◽  
pp. 1179-1183 ◽  
Author(s):  
Ruxandra Draghia-Akli ◽  
Marta L. Fiorotto ◽  
Leigh Anne Hill ◽  
P. Brandon Malone ◽  
Daniel R. Deaver ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone

Good response to long-term therapy with growth hormone in a patient with 9p trisomy syndrome: A case report and review of the literature

2015 ◽  
Vol 170 (4) ◽  
pp. 1046-1049 ◽  
Author(s):  
Ana Pinheiro Machado Canton ◽  
Mirian Yumie Nishi ◽  
Tatiane Katsue Furuya ◽  
Rosimeire Aparecida Roela ◽  
Alexander Augusto Lima Jorge
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Term Therapy ◽  
Review Of The Literature ◽  
Long Term Therapy
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