Plasmid-Based Expression Technology Using Growth Hormone Releasing Hormone: A Novel Method for Physiologically Stimulating Long-Term Growth Hormone Secretion

2006 ◽  
Vol 9 (3) ◽  
pp. 181-185 ◽  
Author(s):  
Ruxandra Draghia-Akli ◽  
Melissa Pope ◽  
Patricia Brown ◽  
Amir Khan
Keyword(s):  
Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Novel Method

Effect of galanin on growth hormone-releasing hormone-stimulated growth hormone secretion in adult patients with nonendocrine diseases on long-term daily glucocorticoid treatment

Metabolism ◽  
1992 ◽  
Vol 41 (5) ◽  
pp. 548-551 ◽  
Author(s):  
Andrea Giustina ◽  
Angela Girelli ◽  
Simonetta Bossoni ◽  
Fabio Legati ◽  
Maurizio Schettino ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Adult Patients ◽  
Growth Hormone Releasing Hormone ◽  
Glucocorticoid Treatment ◽  
Releasing Hormone

Very-low-calorie diet-induced weight reduction reverses impaired growth hormone secretion response to growth hormone-releasing hormone, arginine, and l-dopa in obesity

Metabolism ◽  
1990 ◽  
Vol 39 (9) ◽  
pp. 892-896 ◽  
Author(s):  
Katsuaki Tanaka ◽  
Shuji Inoue ◽  
Kazushi Numata ◽  
Hiroshi Okazaki ◽  
Saburo Nakamura ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Weight Reduction ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Growth Hormone Releasing Hormone ◽  
Very Low Calorie Diet ◽  
Releasing Hormone ◽  
Low Calorie ◽  
Low Calorie Diet ◽  
Calorie Diet

Stimulation and Inhibition of Growth Hormone Secretion by Interleukin-1β; The Involvement of Growth Hormone-Releasing Hormone

1992 ◽  
Vol 56 (1) ◽  
pp. 118-123 ◽  
Author(s):  
Linda C. Payne ◽  
Ferenc Obal, Jr ◽  
Mark R. Opp ◽  
James M. Krueger
Keyword(s):  
Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Interleukin 1Β ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Inhibition Of Growth

Effect of epoxyeicosatrienoic acids on growth hormone release from somatotrophs

1989 ◽  
Vol 256 (2) ◽  
pp. E221-E226 ◽  
Author(s):  
G. D. Snyder ◽  
P. Yadagiri ◽  
J. R. Falck
Keyword(s):  
Growth Hormone ◽  
Arachidonic Acid ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Epoxyeicosatrienoic Acids ◽  
Hormone Release ◽  
Growth Hormone Release ◽  
Growth Hormone Releasing Hormone ◽  
Epoxyeicosatrienoic Acid ◽  
Releasing Hormone

Growth hormone secretion was stimulated in vitro by products of arachidonic acid epoxygenase, the epoxyeicosatrienoic acids. 5,6-Epoxyeicosatrienoic and 14,15-epoxyeicosatrienoic acid stimulated growth hormone release from an enriched population of somatotrophs (approximately 85%) by twofold. Inhibition of arachidonic acid metabolism by indomethacin did not affect growth hormone-releasing hormone stimulation of growth hormone release. In contrast, pretreatment of somatotrophs with an 11,12-isonitrile analogue of arachidonic acid that inhibits arachidonic acid epoxygenase, resulted in a 20-25% inhibition of growth hormone-releasing hormone-stimulated growth hormone release. 14,15-Epoxyeicosatrienoic acid stimulated a concentration-dependent increase (twofold) in the cytoplasmic concentration of adenosine 3',5'-cyclic monophosphate (cAMP) in the somatotrophs. 14,15-Epoxyeicosatrienoic acid also rapidly increased the intracellular free calcium concentration in somatotrophs from resting levels (approximately 80 nM) to greater than 250 nM. Growth hormone-releasing hormone increased the free intracellular calcium to 160-180 nM. Preincubation of somatotrophs with somatostatin inhibited growth hormone-releasing hormone-stimulated growth hormone secretion, cAMP accumulation, and 14,15-epoxyeicosatrienoic acid stimulated cAMP accumulation. These data are suggestive that the epoxyeicosatrienoic acids may have a role in the secretion of growth hormone.

Cholinergic Modulation of Growth Hormone-Releasing Hormone Effects on Growth Hormone Secretion in Dementia

1990 ◽  
Vol 24 (3) ◽  
pp. 129-134 ◽  
Author(s):  
Giovanni Murialdo ◽  
Francesco Zerbi ◽  
Ugo Filippi ◽  
Pietro Tosca ◽  
Stefano Fonzi ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Growth Hormone Releasing Hormone ◽  
Cholinergic Modulation ◽  
Releasing Hormone ◽  
Hormone Effects

Combined Growth Hormone-Releasing Hormone and Growth Hormone-Releasing Peptide-6 Test for the Evaluation of Growth Hormone Secretion in Children with Growth Hormone Deficiency and Growth Hormone Neurosecretory Dysfunction

2008 ◽  
Vol 70 (4) ◽  
pp. 215-223
Author(s):  
Bessie E. Spiliotis ◽  
Dimitrios T. Papadimitriou ◽  
Theodore K. Alexandrides ◽  
Christoforos Karystianos ◽  
George Nikiforidis ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Deficiency ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Hormone Deficiency ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone
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