Low-Dose Adrenocorticotropic Hormone Stimulation Testing in Term Infants

Author(s):  
J.P. Lomenick ◽  
W.J. Smith
2013 ◽  
Vol 243 (3) ◽  
pp. 399-405 ◽  
Author(s):  
Allison J. Stewart ◽  
James C. Wright ◽  
Ellen N. Behrend ◽  
Linda G. Martin ◽  
Robert J. Kemppainen ◽  
...  

2006 ◽  
Vol 22 (11) ◽  
pp. 627-635 ◽  
Author(s):  
Andrea R. Genazzani ◽  
Nicola Pluchino ◽  
Silvia Begliuomini ◽  
Massimo Stomati ◽  
Francesca Bernardi ◽  
...  

2001 ◽  
Vol 67 (5) ◽  
pp. 2304-2309 ◽  
Author(s):  
Arnaud Lacoste ◽  
Fabienne Jalabert ◽  
Shelagh K. Malham ◽  
Anne Cueff ◽  
Serge A. Poulet

ABSTRACT Oysters are permanently exposed to various microbes, and their defense system is continuously solicited to prevent accumulation of invading and pathogenic organisms. Therefore, impairment of the animal's defense system usually results in mass mortalities in cultured oyster stocks or increased bacterial loads in food products intended for human consumption. In the present study, experiments were conducted to examine the effects of stress on the juvenile oyster's resistance to the oyster pathogen Vibrio splendidus. Oysters (Crassostrea gigas) were challenged with a low dose of a pathogenic V. splendidus strain and subjected to a mechanical stress 3 days later. Both mortality andV. splendidus loads increased in stressed oysters, whereas they remained low in unstressed animals. Injection of noradrenaline or adrenocorticotropic hormone, two key components of the oyster neuroendocrine stress response system, also caused higher mortality and increased accumulation of V. splendidus in challenged oysters. These results suggest that the physiological changes imposed by stress, or stress hormones, influenced host-pathogen interactions in oysters and increased juvenile C. gigasvulnerability to Vibrio splendidus.


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