scholarly journals Judicious use of low-dosage corticosteroids for non-severe COVID-19: A case report

Open Medicine ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. 440-445
Author(s):  
Jian Zhang ◽  
Zigang Tian ◽  
Lina Feng ◽  
Zhongming Yang ◽  
Bo Zou ◽  
...  
Keyword(s):  
Case Report ◽  
Lung Injury ◽  
Corticosteroid Therapy ◽  
Complete Recovery ◽  
Evidence Base ◽  
Retrospective Case ◽  
Short Period ◽  
Lung Condition ◽  
Low Dosage ◽  
Systemic Corticosteroid Therapy

Abstract Inflammation-mediated lung injury in severe cases of infection with SARS-CoV-2, the aetiological agent of Coronavirus disease 2019 (COVID-19), can lead to respiratory failure and death, and therapies that block or ameliorate lung injury-associated inflammatory “cytokine storms” and progression to acute respiratory distress syndrome (ARDS) are urgently needed. Therapeutic use of corticosteroids for this purpose has been controversial because of conflicting reports on their efficacy and immunosuppressive behaviour. The WHO has strongly recommended treating critical COVID-19 patients with systemic corticosteroid therapy, but recommends against corticosteroid therapy in non-severe COVID-19 disease because of a lack of strong evidence on its efficacy. This retrospective case report describing the successful treatment of a non-severe COVID-19 case in Changchun, China, by judicious administration of corticosteroids using a personalized therapeutic approach was recorded to strengthen the evidence base showing how corticosteroid use in non-severe COVID-19 cases can be safe and efficacious. Alongside supportive care and lopinavir/ritonavir antiviral drugs, a low dosage of methylprednisolone was administered over a short period to attenuate lung inflammation. Regular chest CT scans guided dosage reduction in response to lesion absorption and improved lung condition. Judicious use of corticosteroids safely attenuated disease progression and facilitated rapid and complete recovery.

scholarly journals Pemphigus vulgaris and complications of systemic corticosteroid therapy: a case report

2003 ◽  
Vol 45 (3) ◽  
pp. 165-169 ◽  
Author(s):  
Elif Eser Sakallioglu ◽  
Gokhan Acikgoz ◽  
Gonca Keles ◽  
Nilgun Senturk ◽  
Filiz Karagoz
Keyword(s):  
Case Report ◽  
Corticosteroid Therapy ◽  
Systemic Corticosteroid ◽  
Pemphigus Vulgaris ◽  
Systemic Corticosteroid Therapy

Āyuṛveda management of keratosis pilaris – a case report

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Rajasadanam Samsakumar Vipinsha ◽  
Changuli Krishna Bhat Prathibha ◽  
Puthanmadom Venkatraramana Sharma Anandaraman
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Symptomatic Relief ◽  
Complete Recovery ◽  
Upper Arm ◽  
Case Presentation ◽  
The Past ◽  
Short Period ◽  
Two Phases ◽  
Universal Treatment

AbstractObjectivesKeratosis pilaris (KP) is the condition of the skin with extensive keratin follicular plugging. It may be associated with the erythema. The upper arm extensor area, shoulders, back of neck and thighs, as well as face and the upper trunk are the areas of presentation. Available medications for KP give only symptomatic relief, while some produce serious side effects. There is no proven universal treatment for the disease that can provide complete recovery. Āyuṛveda management of KP is not yet reported.Case presentationA 26-year-old male patient, presented with main complaints started with papular lesions over his right shoulder, chest and upper back along and later with pustular lesions in the past 2 weeks. The condition was associated with redness, mild swelling and itching. The case was diagnosed as Keratosis pilaris based on its presentation, site, and pathogenesis. Also by analyzing the extent of vitiation of doṣas (morbidities), the Vata kapha pitta hara line of treatment was adopted, which was accomplished in two phases i. e. Śodhana Cikitsa and Śamana Cikitsa.ConclusionBoth internal and external treatments along with diet restrictions were found effective in arresting the pathogenesis and recovery in a short period. All the symptoms associated with the condition were completely cured with no signs of re-occurrence.

scholarly journals Larva migrans: a case report and review

2003 ◽  
Vol 45 (3) ◽  
pp. 167-171 ◽  
Author(s):  
Paulo Eduardo Neves Ferreira Velho ◽  
Andreia Vasconcellos Faria ◽  
Maria Letícia Cintra ◽  
Elemir Macedo de Souza ◽  
Aparecida Machado de Moraes
Keyword(s):  
Case Report ◽  
Natural History ◽  
Corticosteroid Therapy ◽  
Clinical Manifestation ◽  
Systemic Corticosteroid ◽  
Larva Migrans ◽  
Pertinent Literature ◽  
History Of ◽  
Systemic Corticosteroid Therapy

A case of massive Ancylostoma sp. larval infestation is presented in a patient who had received systemic corticosteroid therapy. What attracts attention in this case is the exuberance and rarity of clinical manifestation. Based on the pertinent literature, we discuss the mechanisms of parasital infection, the natural history of the disease and its treatment.

scholarly journals Secondary organizing pneumonia following occupational acute nitrogen oxide poisoning: a case report

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110107
Author(s):  
Shuang Ma ◽  
Baotian Kan ◽  
Xiangdong Jian ◽  
Chenglin Li ◽  
Yingying Zheng ◽  
...  
Keyword(s):  
Case Report ◽  
Lung Injury ◽  
Inflammatory Response ◽  
Nitrogen Oxide ◽  
Complete Recovery ◽  
Pathological Examination ◽  
Organizing Pneumonia ◽  
Mixed Gas ◽  
Systematic Treatment ◽  
Lung Injuries

Secondary organizing pneumonia (SOP) is a nonspecific inflammatory response towards acute lung injuries caused by various diseases. However, organizing pneumonia (OP) secondary to occupational acute nitrogen oxide poisoning has been reported rarely. We report a 49-year-old man who suffered from nitrogen oxide poisoning after inhaling mixed gas at work. After pathological examination, he was diagnosed with OP. In the absence of other underlying factors causing OP, he was diagnosed with SOP owing to acute nitrogen oxide poisoning. After systematic treatment, the patient recovered and was discharged in better health. In patients with lung injury caused by acute nitrogen oxide poisoning, physicians should be alert to the risk of patients subsequently developing SOP, and timely diagnosis and treatment are essential for complete recovery.

Obstacles to Claiming Permanence and Injury-Relatedness for “Posttraumatic” Headache

2009 ◽  
Vol 14 (3) ◽  
pp. 3-6
Author(s):  
Robert J. Barth
Keyword(s):  
Complete Recovery ◽  
World Health ◽  
Related Factors ◽  
Posttraumatic Headache ◽  
Sixth Edition ◽  
Causative Relationship ◽  
Short Period ◽  
The One ◽  
Health Organization ◽  
Subjective Reports

Abstract “Posttraumatic” headaches claims are controversial because they are subjective reports often provided in the complex of litigation, and the underlying pathogenesis is not defined. This article reviews principles and scientific considerations in the AMAGuides to the Evaluation of Permanent Impairment (AMA Guides) that should be noted by evaluators who examine such cases. Some examples in the AMA Guides, Sixth Edition, may seem to imply that mild head trauma can cause permanent impairment due to headache. The author examines scientific findings that present obstacles to claiming that concussion or mild traumatic brain injury is a cause of permanent headache. The World Health Organization, for example, found a favorable prognosis for posttraumatic headache, and complete recovery over a short period of time was the norm. Other studies have highlighted the lack of a dose-response correlation between trauma and prolonged headache complaints, both in terms of the frequency and the severity of trauma. On the one hand, scientific studies have failed to support the hypothesis of a causative relationship between trauma and permanent or prolonged headaches; on the other hand, non–trauma-related factors are strongly associated with complaints of prolonged headache.

Ramsay Hunt syndrome

2012 ◽  
Vol 153 (32) ◽  
pp. 1281-1283
Author(s):  
Róbert Kui ◽  
Zsuzsanna Bata-Csörgő ◽  
Margit Zeher ◽  
Lajos Kemény
Keyword(s):  
Herpes Zoster ◽  
Multidisciplinary Approach ◽  
Systemic Corticosteroid ◽  
Complete Recovery ◽  
Typical Case ◽  
Early Administration ◽  
Ramsay Hunt Syndrome ◽  
Peripheral Facial Palsy ◽  
Hunt Syndrome ◽  
Systemic Corticosteroid Therapy

Ramsay Hunt syndrome is a special form of herpes zoster which is typically characterized by peripheral facial palsy and unilateral herpetic vesicles on the ear. These symptoms are often accompanied by vestibulocochlear dysfunction and other neurological and ophthalmological symptoms. The diagnosis and therapy requires a multidisciplinary approach. The authors present a typical case where the early administration of combined antiviral and systemic corticosteroid therapy led to complete recovery. The authors emphasize the importance of early diagnosis and adequate combination therapy, which improves the prognosis of this disease. Orv. Hetil., 2012, 153, 1281–1283.

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