Age, gender and season dependent 25(OH)D levels in children and adults living in Istanbul

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Zeynep Yildiz ◽  
Özlem Hürmeydan ◽  
Özlem Çakır Madenci ◽  
Asuman Orçun ◽  
Nihal Yücel

AbstractBackgroundWe evaluated population characteristics of serum 25-hydroxyvitamin D (25(OH)D) levels and determined the influence of age, gender and season in an extensive dataset.Materials and methodsLaboratory results of 103,509 adults and 19,186 children were retrospectively evaluated. Study group was classified regarding ages as; <40, 40–50, 50–60 and >60 years for adults and 0–1, 1–12 months,1–3, 4–6, 7–9, 10–12, 13–15 and 16–18 years for children. Seasonal values were also determined. Levels were measured by Architect i1000 SR (Abbott Diagnostics, USA).ResultsThe median (2.5–97.5 percentiles) of 25(OH)D levels were 38.75 (9.5–158.25) nmol/L for adults and 43.25 (11.25–125.5) nmol/L for children. There were significant gender differences for both adults and children. Values differed significantly among age subgroups (p’s < 0.01). A total of 63% of adults and 59.5% of children had 25(OH)D levels below 50 nmol/L (p < 0.001). 25(OH)D levels were significantly lower in the winter compared with summer (p’s < 0.001). Even levels in summer were moderate deficient for all group.ConclusionThe rate of 25(OH)D deficiency was remarkable during the whole year. This will provide large-scale data about 25(OH)D status in Turkish people and may contribute to the prevention and treatment of this condition for better healthcare outcomes.

2021 ◽  
Vol 11 (1) ◽  
pp. 6650-6655
Author(s):  
A. Alghamdi ◽  
T. Alsubait ◽  
A. Baz ◽  
H. Alhakami

Big data have attracted significant attention in recent years, as their hidden potentials that can improve human life, especially when applied in healthcare. Big data is a reasonable collection of useful information allowing new breakthroughs or understandings. This paper reviews the use and effectiveness of data analytics in healthcare, examining secondary data sources such as books, journals, and other reputable publications between 2000 and 2020, utilizing a very strict strategy in keywords. Large scale data have been proven of great importance in healthcare, and therefore there is a need for advanced forms of data analytics, such as diagnostic data and descriptive analysis, for improving healthcare outcomes. The utilization of large-scale data can form the backbone of predictive analytics which is the baseline for future individual outcome prediction.


2009 ◽  
Vol 28 (11) ◽  
pp. 2737-2740
Author(s):  
Xiao ZHANG ◽  
Shan WANG ◽  
Na LIAN

2016 ◽  
Author(s):  
John W. Williams ◽  
◽  
Simon Goring ◽  
Eric Grimm ◽  
Jason McLachlan

2008 ◽  
Vol 9 (10) ◽  
pp. 1373-1381 ◽  
Author(s):  
Ding-yin Xia ◽  
Fei Wu ◽  
Xu-qing Zhang ◽  
Yue-ting Zhuang

2021 ◽  
Vol 77 (2) ◽  
pp. 98-108
Author(s):  
R. M. Churchill ◽  
C. S. Chang ◽  
J. Choi ◽  
J. Wong ◽  
S. Klasky ◽  
...  

Author(s):  
Krzysztof Jurczuk ◽  
Marcin Czajkowski ◽  
Marek Kretowski

AbstractThis paper concerns the evolutionary induction of decision trees (DT) for large-scale data. Such a global approach is one of the alternatives to the top-down inducers. It searches for the tree structure and tests simultaneously and thus gives improvements in the prediction and size of resulting classifiers in many situations. However, it is the population-based and iterative approach that can be too computationally demanding to apply for big data mining directly. The paper demonstrates that this barrier can be overcome by smart distributed/parallel processing. Moreover, we ask the question whether the global approach can truly compete with the greedy systems for large-scale data. For this purpose, we propose a novel multi-GPU approach. It incorporates the knowledge of global DT induction and evolutionary algorithm parallelization together with efficient utilization of memory and computing GPU’s resources. The searches for the tree structure and tests are performed simultaneously on a CPU, while the fitness calculations are delegated to GPUs. Data-parallel decomposition strategy and CUDA framework are applied. Experimental validation is performed on both artificial and real-life datasets. In both cases, the obtained acceleration is very satisfactory. The solution is able to process even billions of instances in a few hours on a single workstation equipped with 4 GPUs. The impact of data characteristics (size and dimension) on convergence and speedup of the evolutionary search is also shown. When the number of GPUs grows, nearly linear scalability is observed what suggests that data size boundaries for evolutionary DT mining are fading.


Sign in / Sign up

Export Citation Format

Share Document