Highly Resolved MR Imaging of Arbitrary Subregions in Large Objects by a Whole-Body Imager

1993 ◽  
Vol 48 (7) ◽  
pp. 753-758
Author(s):  
Karin Pfeffer ◽  
Markus Pfeffer ◽  
Wulf-Ingo Jung ◽  
Otto Lutz ◽  
Fritz Schick

Abstract Highly resolved images of defined regions of interest within extended objects were obtaind with a 1.5 T whole-bode imager and standard hardware. The high-resolution spin echo imaging sequence avoids aliasing and allows pixel resolutions down to 39 µm which are confirmed by phantom measurements. The application of the sequence to large biological objects such as, for example, an amaryllis bulb results in images which provide much detail which could not be resolved with standard sequences.

Radiology ◽  
1990 ◽  
Vol 176 (2) ◽  
pp. 457-460 ◽  
Author(s):  
J Bittoun ◽  
H Saint-Jalmes ◽  
B G Querleux ◽  
L Darrasse ◽  
O Jolivet ◽  
...  

1997 ◽  
Vol 24 (1) ◽  
pp. 61-65 ◽  
Author(s):  
D. Soulié ◽  
Y-S. Cordoliani ◽  
J. Vignaud ◽  
G. Cosnard

Radiology ◽  
1992 ◽  
Vol 184 (3) ◽  
pp. 671-675 ◽  
Author(s):  
R C Smith ◽  
C Reinhold ◽  
T R McCauley ◽  
R C Lange ◽  
R T Constable ◽  
...  

2010 ◽  
Vol 95 (9) ◽  
pp. 4192-4196 ◽  
Author(s):  
Russell R. Lonser ◽  
Bogdan A. Kindzelski ◽  
Gautam U. Mehta ◽  
John A. Jane ◽  
Edward H. Oldfield

Context: GH-secreting pituitary adenomas are nearly always visible on conventional magnetic resonance (MR) imaging. However, management and outcome of acromegalic patients lacking imaging evidence of GH-secreting pituitary adenomas are undefined. Objective: The aim was to evaluate surgical exploration for MR-invisible GH-secreting pituitary adenomas. Design and Setting: We conducted a retrospective review at two tertiary care centers. Patients or Other Participants: Consecutive acromegalic patients without imaging evidence of a pituitary adenoma on pre- and postcontrast, spin echo T1-weighted MR imaging and who lacked evidence of an ectopic (nonpituitary) source causing GH excess were included. Interventions: Surgical exploration with identification and resection of a pituitary adenoma was performed. Main Outcome Measures: Laboratory values (GH, IGF-I), surgical findings, and clinical outcome were analyzed. Results: Six patients (three males, three females; 3% of all patients) with suspected GH-secreting adenomas did not demonstrate imaging evidence of pituitary adenoma on conventional MR imaging. Three patients underwent a postcontrast, volumetric interpolated breath-hold examination MR-imaging sequence (1.2-mm slice thickness), which revealed a 4-mm pituitary adenoma not seen on the spin echo T1-weighted MR imaging in one patient. A pituitary adenoma was identified and removed in all patients (mean diameter, 5.6 mm; range, 5 to 6.7 mm). Histological analysis confirmed that the lesions were GH-secreting adenomas. All patients achieved biochemical remission after surgical resection. Conclusion: Acromegaly can be caused by GH-secreting pituitary adenomas that are not evident on conventional MR imaging. Adenomas in some of these patients become evident using volumetric interpolated breath-hold examination MR imaging. Surgical exploration of the pituitary gland in acromegalic patients with endocrine findings consistent with a GH-secreting adenoma but negative MR imaging can lead to identification and removal of an adenoma.


1997 ◽  
Vol 4 (12) ◽  
pp. 849
Author(s):  
James G. Waldschmidt ◽  
Robert J. Rilling ◽  
Scott J. Erickson ◽  
A.A. Kajdacsay-Balla ◽  
R. Latoraca ◽  
...  

1992 ◽  
Vol 159 (2) ◽  
pp. 395-398 ◽  
Author(s):  
R D Tien ◽  
G J Felsberg ◽  
J Macfall

2018 ◽  
Vol 39 (6) ◽  
pp. 1065-1067 ◽  
Author(s):  
E. Kalsoum ◽  
A. Chabernaud Negrier ◽  
T. Tuilier ◽  
A. Benaïssa ◽  
R. Blanc ◽  
...  

Author(s):  
H.A. Cohen ◽  
T.W. Jeng ◽  
W. Chiu

This tutorial will discuss the methodology of low dose electron diffraction and imaging of crystalline biological objects, the problems of data interpretation for two-dimensional projected density maps of glucose embedded protein crystals, the factors to be considered in combining tilt data from three-dimensional crystals, and finally, the prospects of achieving a high resolution three-dimensional density map of a biological crystal. This methodology will be illustrated using two proteins under investigation in our laboratory, the T4 DNA helix destabilizing protein gp32*I and the crotoxin complex crystal.


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