Reaction of N-Arylphthalisoimidium Perchlorates with Amines and Aromatic Hydrocarbons under Friedel-Crafts Conditions, a New and Convenient One-Step Method for the Synthesis of 2,3-Diaryl-3-hydroxyphthalimidines

1990 ◽  
Vol 45 (5) ◽  
pp. 707-710 ◽  
Author(s):  
M. Fekry Ismail ◽  
E. I. Enayat ◽  
F. A. El-Bassiouny ◽  
H. A. Younes
Keyword(s):  
Aromatic Hydrocarbons ◽  
Ring Opening ◽  
Primary Amines ◽  
Step Method ◽  
One Step ◽  
Phenylmagnesium Bromide

N-Arylphthalisoimidium perchlorates (1 a, b) react with primary amines via ring-opening to give N,N′-disubstituted phthalamides (3a—d). They react with aromatic hydrocarbons under Friedel-Crafts conditions to give 2,3-diaryl-3-hydroxyphthalimidines (a—i) while the reaction of 1 a with phenylmagnesium bromide involved just deprotonation to the isoimide (9) followed by rearrangement to N-phenylphthalimide (8).

scholarly journals Zirconium (IV) Acetylacetonate: Ring-Opening Initiator Mediating One-Step Synthesis of Biodegradable Polyacids

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Piotr Dobrzyński ◽  
Małgorzata Pastusiak ◽  
Joanna Jaworska ◽  
Bożena Kaczmarczyk ◽  
Michał Kwiecień ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Acid Derivative ◽  
Ring Opening ◽  
Active Catalyst ◽  
Ring Opening Polymerization ◽  
Cyclic Carbonate ◽  
Trimethylene Carbonate ◽  
Step Method ◽  
Polymerization Mechanism ◽  
One Step

Biodegradable polyacid is obtained in one-step ring-opening polymerization (ROP) of carboxylic-acid-functionalized six-membered cyclic carbonate mediated with zirconium (IV) acetylacetonate. Exemplary copolymers with L,L-lactide are described as well. Moreover, zirconium (IV) acetylacetonate is found to be active catalyst of trimethylene carbonate (TMC) ROP in presence of carboxylic acid yielding PTMC end-capped with the acid derivative. Polymerization mechanism is hypothesized demonstrating possibilities of the method in work-saving polycation synthesis and one-step method of conjugate synthesis of well-known biocompatible polyesters and polycarbonates.

ChemInform Abstract: Nucleophilic Ring-Opening of Activated Aziridines: A One-Step Method for Labeling Biomolecules with Fluorine-18.

ChemInform ◽  
2010 ◽  
Vol 41 (4) ◽  
Author(s):  
Ulrike Roehn ◽  
Jessica Becaud ◽  
Linjing Mu ◽  
Ananth Srinivasan ◽  
Timo Stellfeld ◽  
...  
Keyword(s):  
Ring Opening ◽  
Step Method ◽  
One Step ◽  
Nucleophilic Ring Opening

Nucleophilic ring-opening of activated aziridines: A one-step method for labeling biomolecules with fluorine-18

2009 ◽  
Vol 130 (10) ◽  
pp. 902-912 ◽  
Author(s):  
Ulrike Roehn ◽  
Jessica Becaud ◽  
Linjing Mu ◽  
Ananth Srinivasan ◽  
Timo Stellfeld ◽  
...  
Keyword(s):  
Ring Opening ◽  
Step Method ◽  
One Step ◽  
Nucleophilic Ring Opening

Effect of Dynamic Crosslinking on Mechanical Properties of PP/EPDM Blends

1993 ◽  
Vol 58 (11) ◽  
pp. 2642-2650 ◽  
Author(s):  
Zdeněk Kruliš ◽  
Ivan Fortelný ◽  
Josef Kovář
Keyword(s):  
Mechanical Properties ◽  
Impact Strength ◽  
Shear Modulus ◽  
High Impact ◽  
Necessary Condition ◽  
Step Method ◽  
Melt Mixing ◽  
One Step ◽  
High Impact Strength ◽  
Dynamic Curing

The effect of dynamic curing of PP/EPDM blends with sulfur and thiuram disulfide systems on their mechanical properties was studied. The results were interpreted using the knowledge of the formation of phase structure in the blends during their melt mixing. It was shown, that a sufficiently slow curing reaction is necessary if a high impact strength is to be obtained. Only in such case, a fine and homogeneous dispersion of elastomer can be formed, which is the necessary condition for high impact strength of the blend. Using an inhibitor of curing in the system and a one-step method of dynamic curing leads to an increase in impact strength of blends. From the comparison of shear modulus and impact strength values, it follows that, at the stiffness, the dynamically cured blends have higher impact strength than the uncured ones.

Ruthenium-catalyzed synthesis of N-substituted lactams by acceptorless dehydrogenative coupling of diols with primary amines

2019 ◽  
Vol 55 (82) ◽  
pp. 12384-12387 ◽  
Author(s):  
Yanling Zheng ◽  
Xufeng Nie ◽  
Yang Long ◽  
Li Ji ◽  
Haiyan Fu ◽  
...  
Keyword(s):  
Phosphine Ligand ◽  
Primary Amines ◽  
Dehydrogenative Coupling ◽  
One Step

The first synthesis of N-substituted lactams via an acceptorless dehydrogenative coupling of diols with primary amines in one step was enabled by combining Ru3(CO)12 with a hybrid N-heterocyclic carbene–phosphine–phosphine ligand as the catalyst.

Bismuth particles imbedded degradable nanohydrogel prepared by one-step method for tumor dual-mode imaging and chemo-photothermal combined therapy

2019 ◽  
Vol 375 ◽  
pp. 122000 ◽  
Author(s):  
Yang Xuan ◽  
Xian-Lin Song ◽  
Xiao-Quan Yang ◽  
Ruo-Yun Zhang ◽  
Zi-Yu Song ◽  
...  
Keyword(s):  
Combined Therapy ◽  
Dual Mode ◽  
Step Method ◽  
One Step
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