Multifunctional nanoparticles of Fe3O4@SiO2(FITC)/PAH conjugated the recombinant plasmid of pIRSE2-EGFP/VEGF165with dual functions for gene delivery and cellular imaging

2012 ◽  
Vol 9 (10) ◽  
pp. 1197-1207 ◽  
Author(s):  
Yiyao Liu ◽  
Mengran Shi ◽  
Mingming Xu ◽  
Hong Yang ◽  
Chunhui Wu
2007 ◽  
Author(s):  
Mary-Margaret Seale ◽  
Dimitry Zemlyanov ◽  
Christy L. Cooper ◽  
Emily Haglund ◽  
Tarl W. Prow ◽  
...  

2005 ◽  
Vol 117 (7) ◽  
pp. 1092-1095 ◽  
Author(s):  
Tae-Jong Yoon ◽  
Jun Sung Kim ◽  
Byung Geol Kim ◽  
Kyeong Nam Yu ◽  
Myung-Haing Cho ◽  
...  

1995 ◽  
Vol 268 (6) ◽  
pp. L1052-L1056 ◽  
Author(s):  
M. F. Tsan ◽  
J. E. White ◽  
B. Shepard

A number of gene delivery methods have been developed to facilitate gene transfer into mammalian somatic cells in vivo. In this study, we demonstrated that tracheal insufflation of two recombinant plasmids containing a bacterial gene, chloramphenicol acetyltransferase (CAT), driven by the cytomegalovirus (CMV) immediate early promoter/enhancer, either alone or complexed to cationic liposomes, resulted in efficient and selective transfection of the lungs in rats. When the simian virus 40 (SV40) promoter/enhancer was used, there was no detectable transfection. Insufflation of plasmid DNA was as efficient as plasmid-liposome complexes in transfecting the lungs. Expression of the CAT gene in the lungs was noted as early as 1 day after insufflation of plasmid DNA alone or plasmid-liposome complexes, and lasted for > 21 days. In contrast, intravenous injection of plasmid alone or plasmid-liposome complexes did not result in transfection of the lungs. Because of its simplicity, without the potential adverse effect of any gene delivery systems, intratracheal delivery of recombinant plasmid DNA may have potential implication for lung-specific gene therapy.


2005 ◽  
Vol 44 (7) ◽  
pp. 1068-1071 ◽  
Author(s):  
Tae-Jong Yoon ◽  
Jun Sung Kim ◽  
Byung Geol Kim ◽  
Kyeong Nam Yu ◽  
Myung-Haing Cho ◽  
...  

2017 ◽  
Vol 8 (48) ◽  
pp. 7486-7498 ◽  
Author(s):  
Bing Wang ◽  
Ping Chen ◽  
Ji Zhang ◽  
Xiao-Chuan Chen ◽  
Yan-Hong Liu ◽  
...  

Core–shell-corona multifunctional nanoparticles were prepared and used for cell imaging and cell-targeting delivery of genes toward hepatocytes.


2014 ◽  
Vol 50 (13) ◽  
pp. 1579 ◽  
Author(s):  
Wenyu Li ◽  
Jianwei Du ◽  
Kun Zheng ◽  
Peng Zhang ◽  
Qiaoling Hu ◽  
...  

2015 ◽  
Vol 103 (11) ◽  
pp. 3474-3482 ◽  
Author(s):  
So-Jung Gwak ◽  
Heebeom Koo ◽  
Yeomin Yun ◽  
Ji Young Yhee ◽  
Hye Yeong Lee ◽  
...  

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