Pharmacologic normal tissue protection in clinical radiation oncology: focus on amifostine

2008 ◽  
Vol 4 (10) ◽  
pp. 1341-1350 ◽  
Author(s):  
Loren K Mell ◽  
Benjamin Movsas
2021 ◽  
Vol 10 (4) ◽  
pp. 3199-3201
Author(s):  
Anurag A. Luharia

Advancements in Radiation Oncology from conventional to 3D conformal radiotherapy treatment demands expertise in many steps of radiation planning, the horizon of radiologist is now expanded by many folds and made radiologist as a integral part of the Radiation Oncology Department. A critical aspect of radiotherapy treatment planning (RTP) is determining how to deliver the required radiation dosage to cancer cells while minimising the exposure to normal tissue for which the prerequisite is identification and accurate delineation of tumour volume as well as normal structure resulted in an increase in the therapeutic ratio by reducing complication associated with normal tissue and allowing for higher target dosage and better local control. In modern radiotherapy CT images are the standard set of imaging modality required for the radiotherapy planning along with it many other modalities like MRI, PET or DSA are used by superimposing on original CT images in order to contour or delineate the structures defined by International Commission on Radiation Units and Measurements in Reports 50, 62 and 71 (ICRU) for radiotherapy planning which comprise of Gross tumour volume, clinical target volume, planning target volume, irradiated volume, Internal target volume and the normal structures as Organ at risk. It is self-evident that the contribution of a radiologist with a thorough knowledge of the development of these new modalities is critical for optimising the potential of these novel modes of radiation treatment delivery.


2019 ◽  
Vol 3 (2) ◽  
pp. 145-155 ◽  
Author(s):  
Samir V. Jenkins ◽  
Dmitry A. Nedosekin ◽  
Barry J. Shaulis ◽  
Tengjiao Wang ◽  
Azemat Jamshidi-Parsian ◽  
...  

2008 ◽  
Vol 72 (1) ◽  
pp. S697-S698 ◽  
Author(s):  
D. Kornguth ◽  
J. Su ◽  
X. Li ◽  
K. Ang ◽  
S. Blaney ◽  
...  

2019 ◽  
Vol 9 ◽  
Author(s):  
Giuseppe Palma ◽  
Serena Monti ◽  
Amedeo Buonanno ◽  
Roberto Pacelli ◽  
Laura Cella

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