scholarly journals Erratum: Li et al., “The DNA Repair-Associated Protein Gadd45γ Regulates the Temporal Coding of Immediate Early Gene Expression within the Prelimbic Prefrontal Cortex and Is Required for the Consolidation of Associative Fear Memory”

2019 ◽  
Vol 39 (20) ◽  
pp. 3993.1-3993
Keyword(s):  
Gene Expression ◽  
Dna Repair ◽  
Prefrontal Cortex ◽  
Immediate Early Gene ◽  
Fear Memory ◽  
Temporal Coding ◽  
Early Gene ◽  
Immediate Early ◽  
Early Gene Expression

Effects of cocaine base paste on anxiety-like behavior and immediate-early gene expression in nucleus accumbens and medial prefrontal cortex of female mice

2019 ◽  
Vol 236 (12) ◽  
pp. 3525-3539 ◽  
Author(s):  
Bruno G. Berardino ◽  
Estefanía A. Fesser ◽  
Laura M. Belluscio ◽  
Octavio Gianatiempo ◽  
Nicolás Pregi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Prefrontal Cortex ◽  
Nucleus Accumbens ◽  
Medial Prefrontal Cortex ◽  
Immediate Early Gene ◽  
Early Gene ◽  
Immediate Early ◽  
Early Gene Expression ◽  
Female Mice ◽  
Cocaine Base

Cocaine reverses the naltrexone-induced reduction in operant ethanol self-administration: The effects on immediate-early gene expression in the rat prefrontal cortex

2012 ◽  
Vol 63 (6) ◽  
pp. 927-935 ◽  
Author(s):  
Víctor Echeverry-Alzate ◽  
María Tuda-Arízcun ◽  
Kora-Mareen Bühler ◽  
Ángel Santos ◽  
Elena Giné ◽  
...  
Keyword(s):  
Gene Expression ◽  
Prefrontal Cortex ◽  
Immediate Early Gene ◽  
Early Gene ◽  
Immediate Early ◽  
Self Administration ◽  
Early Gene Expression

The muscarinic agonist xanomeline increases monoamine release and immediate early gene expression in the rat prefrontal cortex

2001 ◽  
Vol 49 (8) ◽  
pp. 716-725 ◽  
Author(s):  
Kenneth W Perry ◽  
Laura K Nisenbaum ◽  
Carolyn A George ◽  
Harlan E Shannon ◽  
Christian C Felder ◽  
...  
Keyword(s):  
Gene Expression ◽  
Prefrontal Cortex ◽  
Immediate Early Gene ◽  
Early Gene ◽  
Immediate Early ◽  
Muscarinic Agonist ◽  
Early Gene Expression ◽  
Monoamine Release

scholarly journals The DNA repair associated protein Gadd45γ regulates the temporal coding of immediate early gene expression and is required for the consolidation of associative fear memory

2018 ◽  
Author(s):  
Xiang Li ◽  
Paul R. Marshall ◽  
Laura J. Leighton ◽  
Esmi L. Zajaczkowski ◽  
Timothy W. Bredy ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Dna Repair ◽  
Memory Consolidation ◽  
Immediate Early Gene ◽  
Fear Memory ◽  
Dna Demethylation ◽  
Temporal Coding ◽  
Early Gene ◽  
Immediate Early ◽  
Active Dna Demethylation

AbstractVisual abstractWe have identified a member of the Growth arrest and DNA damage (Gadd45) family, Gadd45γ, which is known to be involved in the regulation of DNA repair, as a key player in the formation of associative fear memory. Gadd45γ regulates the temporal dynamics of learning-induced immediate early gene (IEG) expression in the prelimbic prefrontal cortex through its interaction with DNA double-strand break (DSB)-mediated changes in DNA methylation. Our findings suggest a two-hit model of experience-dependent IEG activity and learning that comprises 1) a first wave of IEG expression governed by DSBs followed by an increase in DNA methylation, and 2) a second wave of IEG expression associated with Gadd45γ and active DNA demethylation at the same site, which is necessary for memory consolidation.Significance statementHow does the pattern of immediate early gene (IEG) transcription in the brain relate to the storage and accession of information, and what controls these patterns? This paper explores how GADD45γ, a gene that is known to be involved with DNA modification and repair, regulates the temporal coding of IEGs underlying associative learning and memory. We reveal that, during fear learning, GADD45γ serves to act as a coordinator of IEG expression and subsequent memory consolidation by directing temporally specific changes in active DNA demethylation at the promoter of plasticity-related IEGs.

Phylogenetic relatedness and immediate early gene expression in black-capped chickadees

2012 ◽  
Author(s):  
Christopher B. Sturdy ◽  
Marc T. Avey ◽  
Laurie L. Bloomfield ◽  
Julie E. Elie ◽  
Todd M. Freeberg ◽  
...  
Keyword(s):  
Gene Expression ◽  
Immediate Early Gene ◽  
Early Gene ◽  
Immediate Early ◽  
Phylogenetic Relatedness ◽  
Early Gene Expression
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