scholarly journals Deletion of Kv4.2 Gene Eliminates Dendritic A-Type K+ Current and Enhances Induction of Long-Term Potentiation in Hippocampal CA1 Pyramidal Neurons

2006 ◽  
Vol 26 (47) ◽  
pp. 12143-12151 ◽  
Author(s):  
X. Chen ◽  
L.-L. Yuan ◽  
C. Zhao ◽  
S. G. Birnbaum ◽  
A. Frick ◽  
...  
Keyword(s):  
Pyramidal Neurons ◽  
Long Term Potentiation ◽  
Ca1 Pyramidal Neurons ◽  
Type K ◽  
Term Potentiation ◽  
Hippocampal Ca1 ◽  
K Current

scholarly journals Extrasynaptic NMDA receptor dependent long-term potentiation of hippocampal CA1 pyramidal neurons

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Qian Yang ◽  
Geng Zhu ◽  
Dandan Liu ◽  
Jue-Gang Ju ◽  
Zhen-Hua Liao ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Pyramidal Neurons ◽  
Long Term Potentiation ◽  
Ca1 Pyramidal Neurons ◽  
Term Potentiation ◽  
Hippocampal Ca1

The involvement of nonspiking cells in long-term potentiation of synaptic transmission in the hippocampus

1988 ◽  
Vol 66 (6) ◽  
pp. 841-844 ◽  
Author(s):  
B. R. Sastry ◽  
J. W. Goh ◽  
P. B. Y. May ◽  
S. S. Chirwa
Keyword(s):  
Pyramidal Neurons ◽  
Hippocampal Slices ◽  
Long Term Potentiation ◽  
Stratum Radiatum ◽  
Ca1 Pyramidal Neurons ◽  
Term Potentiation ◽  
Ca1 Area ◽  
Glial Depolarization ◽  
Stimulation Of

In guinea pig hippocampal slices, stimulation of stratum radiatum during depolarization (with intracellular current injections) of nonspiking cells (presumed to be glia) in the apical dendritic area of CA1 pyramidal neurons resulted in a subsequent long-term potentiation of intracellularly recorded excitatory postsynaptic potentials as well as extracellularly recorded population spikes in the CA1 area. Tetanic stimulation of stratum radiatum resulted in a subsequent prolonged depolarization of the presumed glial cells, and this depolarization was smaller when the tetanus was given during the presence of 2-amino-5-phosphonovalerate or when the slices were exposed to Ca2+-free medium containing Mn2+ and Mg2+. These results suggest that glial depolarization is involved as one of the steps in generating long-term potentiation.

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