Does growth hormone therapy increase the frequency of tumor recurrence in children with brain tumors?

1987 ◽  
Vol 116 (3_Suppl) ◽  
pp. S188-S189 ◽  
Author(s):  
K.P. RODENS ◽  
S.L. KAPLAN ◽  
M.M. GRUMBACH ◽  
W.M. TELLER
Keyword(s):  
Growth Hormone ◽  
Brain Tumors ◽  
Hormone Therapy ◽  
Tumor Recurrence ◽  
Growth Hormone Therapy

Growth Hormone Therapy and the Risk of Tumor Recurrence after Brain Tumor Treatment in Children

2010 ◽  
Vol 23 (9) ◽  
Author(s):  
Tilman R. Rohrer ◽  
Thorsten Langer ◽  
Gerhard G. Grabenbauer ◽  
Michael Buchfelder ◽  
Matthias Glowatzki ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Brain Tumor ◽  
Hormone Therapy ◽  
Tumor Recurrence ◽  
Growth Hormone Therapy ◽  
Tumor Treatment

Occurrence of Cranial Neoplasms in Pediatric Patients with Noonan Syndrome Receiving Growth Hormone: Is Screening with Brain MRI prior to Initiation of Growth Hormone Indicated?

2017 ◽  
Vol 88 (6) ◽  
pp. 423-426 ◽  
Author(s):  
Kanthi Bangalore Krishna ◽  
Pedro Pagan ◽  
Oscar Escobar ◽  
Jadranka Popovic
Keyword(s):  
Growth Hormone ◽  
Brain Tumors ◽  
Hormone Therapy ◽  
Noonan Syndrome ◽  
Growth Hormone Treatment ◽  
Growth Hormone Therapy ◽  
Brain Mri ◽  
Hormone Treatment ◽  
Tumor Burden ◽  
Primary Brain Tumors

Noonan syndrome (NS) is associated with short stature. Growth hormone treatment has been FDA approved for use in these patients. Children with NS are at a higher risk of developing benign and malignant proliferative disorders, primary brain tumors being one of them. Since growth hormone therapy can worsen the tumor burden, screening with a brain MRI prior to growth hormone initiation in NS patients is strongly recommended. Here we present two NS patients who developed different primary brain tumors while being on growth hormone therapy.

scholarly journals A second KIGS communication on side effects of growth hormone therapy

1993 ◽  
Vol 39 (5) ◽  
pp. 85-88
Author(s):  
P. J. Chatlein ◽  
P. Wilton
Keyword(s):  
Growth Hormone ◽  
Side Effects ◽  
Brain Tumors ◽  
Hormone Therapy ◽  
Bone Tissue ◽  
Growth Hormone Therapy ◽  
Gh Therapy ◽  
One Year

By March 25, 1992, among the 16,604 patients included in the KIGS database who had been treated with growth hormone (GH) for at least one year, 135 had serious side effects (SE). Among the most frequent SE are relapses of craniopharyngioma (17) and other brain tumors (11). Changes in bone tissue, joints and muscles were more rarely observed. 7 patients had convulsive syndrome. More information is needed to assess the effect of GH therapy on these complications.

Occurrence of DNET and other brain tumors in Noonan syndrome warrants caution with growth hormone therapy

2015 ◽  
Vol 170 (1) ◽  
pp. 195-201 ◽  
Author(s):  
Geoffrey D. McWilliams ◽  
Karen SantaCruz ◽  
Blaine Hart ◽  
Carol Clericuzio
Keyword(s):  
Growth Hormone ◽  
Brain Tumors ◽  
Hormone Therapy ◽  
Noonan Syndrome ◽  
Growth Hormone Therapy

Growth hormone therapy in a child with severe short stature due to Miller-McKusick-Malvaux (3M) syndrome-2

2019 ◽  
Author(s):  
Sumudu Seneviratne ◽  
Deepthi de Silva ◽  
Emily Cottrell ◽  
Piumi Kuruppu ◽  
KSH de Silva ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Therapy ◽  
Short Stature ◽  
Growth Hormone Therapy ◽  
Severe Short Stature
Sign in / Sign up

Export Citation Format

Share Document