Clinical assessment of trabecular bone microstructure in type 2 diabetes mellitus with Trabecular Bone Score (TBS)

2017 ◽  
Author(s):  
Maria Dolores Aviles Perez ◽  
Antonia Garcia Martin ◽  
Cristina Novo Rodriguez ◽  
Rafael Nieto Serrano ◽  
Elena Torres Vela ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Trabecular Bone ◽  
Clinical Assessment ◽  
Trabecular Bone Score ◽  
Bone Microstructure ◽  
Trabecular Bone Microstructure

Trabecular bone score and insulin resistance in type 2 diabetes mellitus

2020 ◽  
Author(s):  
Ponce Maria Hayon ◽  
Laguna Mª del Carmen Serrano ◽  
Perez Maria Dolores Aviles ◽  
Beatriz Garcia Fontana ◽  
Sheila Gonzalez Salvatierra ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Trabecular Bone ◽  
Trabecular Bone Score

Trabecular Bone Score in Thais with or without Type 2 Diabetes

2020 ◽  
Vol 103 (11) ◽  
pp. 1131-1137
Keyword(s):  
Diabetes Mellitus ◽  
Bone Mineral Density ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Fracture Risk ◽  
Trabecular Bone ◽  
Trabecular Bone Score ◽  
Mineral Density ◽  
Men And Women

Background: When compared to people without type 2 diabetes mellitus (T2DM), people with T2DM have an increase in fracture risk despite having higher bone mineral density (BMD). Many studies in Caucasians demonstrated that trabecular bone score (TBS) is lower in people with T2DM than those without. The utility of TBS as a fracture risk assessment tool in Asians with T2DM is currently unclear. Objective: To compared lumbar spine (LS) BMD and TBS in Thais with or without T2DM and investigate the correlation between TBS and hemoglobin A1c (HbA1c) and diabetes duration in participants with T2DM. Materials and Methods: The present study was a cross-sectional study that included 97 participants with T2DM (37 men and 60 women) and 342 participants without T2DM (174 men and 168 women). LS-BMD and TBS were obtained. Results: Men and women with T2DM were older and had higher body mass index (BMI). Men with T2DM had significant higher LS-BMD (1.051±0.166 versus 0.972±0.125, p=0.009) and non-significant lower TBS (1.333±0.084 versus 1.365±0.096, p=0.055) than those without. Similarly, women with T2DM had significant higher LS-BMD (0.995±0.155 versus 0.949±0.124, p=0.021) and lower TBS (1.292±0.105 versus 1.382±0.096, p<0.001). After adjusting for age and BMI, T2DM predicted higher BMD in men (p<0.001), but not in women (p=0.143). T2DM was not associated with TBS after adjusting for age and BMI in both genders (p=0.403 and p=0.151 in men and women, respectively). TBS did not correlate with HbA1c in both genders. However, TBS was non-significantly associated with diabetes duration in women (p=0.073), but not in men (p=0.639). Conclusion: T2DM significantly predicted higher LS-BMD only in men and was not independently associated with TBS in both genders. These data highlighted that, in T2DM, there was some variation in the clinical usefulness of BMD and TBS in predicting osteoporotic fractures with regard to clinical characteristic of participants. Keywords: Bone mineral density, Type 2 diabetes mellitus, Trabecular bone score

Assessment of bone quality with trabecular bone score in type 2 diabetes mellitus: A study from the FRISBEE cohort

2019 ◽  
Vol 73 (5) ◽  
pp. e13347 ◽  
Author(s):  
Felicia Baleanu ◽  
Pierre Bergmann ◽  
Anne Sophie Hambye ◽  
Carole Dekelver ◽  
Laura Iconaru ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Trabecular Bone ◽  
Bone Quality ◽  
Trabecular Bone Score

scholarly journals Osteosarcopenia and trabecular bone score in patients with type 2 diabetes mellitus

2021 ◽  
Author(s):  
Luciana Muniz Pechmann ◽  
Ricardo R. Petterle ◽  
Carolina A. Moreira ◽  
Victoria Z. C. Borba
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Trabecular Bone ◽  
Trabecular Bone Score

Relationship between muscle function and trabecular bone score (TBS) in Type 2 diabetes mellitus

2021 ◽  
Author(s):  
Maria Hayon Ponce ◽  
David Blanquez Martinez ◽  
del Carmen Serrano Laguna Mª ◽  
Dolores Aviles Perez Maria ◽  
Beatriz Garcia Fontana ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Trabecular Bone ◽  
Muscle Function ◽  
Trabecular Bone Score

Lower trabecular bone score in type 2 diabetes mellitus: a role for fat mass and insulin resistance beyond hyperglycaemia

2021 ◽  
pp. 101276
Author(s):  
María Hayón-Ponce ◽  
Beatriz García-Fontana ◽  
María Dolores Avilés-Pérez ◽  
Sheila González-Salvatierra ◽  
Francisco Andújar-Vera ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Trabecular Bone ◽  
Fat Mass ◽  
Trabecular Bone Score

Comparison of trabecular bone score and hip structural analysis with FRAX® in postmenopausal women with type 2 diabetes mellitus

2016 ◽  
Vol 29 (5) ◽  
pp. 951-957 ◽  
Author(s):  
Gloria Bonaccorsi ◽  
Enrica Fila ◽  
Carmelo Messina ◽  
Elisa Maietti ◽  
Fabio Massimo Ulivieri ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Structural Analysis ◽  
Trabecular Bone ◽  
Postmenopausal Women ◽  
Trabecular Bone Score ◽  
Hip Structural Analysis

scholarly journals Trabecular bone score for the diagnostics of osteoporosis in subjects with type 2 diabetes mellitus: a clinical case

2017 ◽  
Vol 20 (1) ◽  
pp. 22-27
Author(s):  
Tatiana A. Grebennikova ◽  
Zhanna E. Belaya
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Fracture Risk ◽  
Trabecular Bone ◽  
Clinical Case ◽  
Trabecular Bone Score ◽  
Bone Microarchitecture ◽  
Mineral Density

Type 2 diabetes mellitus (T2DM) is associated with higher fracture risk but, better bone mineral density (BMD). Alteration of the skeletal material or microstructure may be an underlying mechanism for the discrepancy between BMD and fracture risk in diabetes. The trabecular bone score has been proposed as an indirect measurement of bone microarchitecture with the routine dual energy absorptiometry.  We present a clinical case of diagnosis and treatment of osteoporosis associated with T2DM in patient with a low-trauma fracture and concomitant endocrine disorder.

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