Cardiovascular and metabolic safety of growth hormone treatment in adult patients with growth hormone deficiency: real-world data from two large studies in the USA and Europe

2021 ◽  
Author(s):  
Höybye Charlotte ◽  
Nicky Kelepouris ◽  
Navid Nedjatian
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Deficiency ◽  
Real World ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Adult Patients ◽  
Hormone Deficiency ◽  
Real World Data ◽  
World Data ◽  
The Usa

scholarly journals Early growth hormone treatment accelerates delayed onset of puberty in patients with growth hormone deficiency

2021 ◽  
Author(s):  
Toshiaki Tanaka ◽  
Shun Soneda ◽  
Naoko Sato ◽  
Kentaro Kishi ◽  
Masahiro Noda ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Deficiency ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Early Growth ◽  
Hormone Deficiency ◽  
Delayed Onset

Growth Hormone Treatment in Adults with Growth Hormone Deficiency

1993 ◽  
pp. 288-301
Author(s):  
A. J. Weissberger ◽  
R. C. Cuneo ◽  
F. Salomon ◽  
G. A. McGauley ◽  
C. Lowy ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Deficiency ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Hormone Deficiency

WHAT POTENTIALLY MODIFIABLE FACTORS ARE ASSOCIATED WITH TREATMENT NON-ADHERENCE IN PAEDIATRIC GROWTH HORMONE DEFICIENCY? A QUANTITATIVE STUDY

2020 ◽  
Author(s):  
Selina Graham ◽  
Samantha Neo ◽  
Vivian Auyeung ◽  
John Weinman
Keyword(s):  
Growth Hormone ◽  
Medication Adherence ◽  
Healthcare Professional ◽  
Growth Hormone Deficiency ◽  
Treatment Adherence ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Hormone Deficiency ◽  
Modifiable Factors ◽  
Adherence Scale

Objective: A recent systematic review reported that up to 71% of patients with growth hormone deficiency and their families are non-adherent to treatment as prescribed. Non-adherence to growth hormone treatment presents a substantial and costly problem for the patient, healthcare provider and healthcare system. The current study uniquely investigates the potentially modifiable factors associated with treatment non-adherence in this endocrine disorder. Methods: The cross-sectional study was conducted among 82 parent/caregivers of children with growth hormone deficiency and receiving growth hormone treatment. Self-report questionnaires investigated parents/caregivers’ perceptions and experiences of their child’s condition and prescribed treatment, in addition to their perceived relationship with their healthcare professional. The eight-item Morisky Medication Adherence Scale was used for the assessment of treatment adherence. Results: 62% of parent/caregivers were found to be non-adherent to growth hormone treatment as prescribed. Illness perceptions [consequences, identity and coherence] and treatment concerns were found to be significantly associated with treatment adherence, as was the quality of the healthcare professional-parent/caregiver relationship. Conclusion: The study confirms the extent of the adherence problem evident amongst the paediatric growth hormone deficiency population. In addition, it presents an insight into the explanatory factors that underpin non-adherence to growth hormone treatment. Our findings can be used to inform the development of adherence-focussed interventions, with the purpose to support patients and their families and improve the use of prescribed growth hormone treatment within endocrine clinical practice. Abbreviations: GHD = Growth Hormone Deficiency; rhGH = Recombinant Human Growth Hormone treatment; HCP = Healthcare Professional; MMAS = Morisky Medication Adherence Scale; BIPQ = Brief Illness Perception Questionnaire; BMQ = Beliefs about Medicines Questionnaires-Specific; PHR = Parent-Healthcare Provider Relationship-AIRS© Section II; COM-B = Capability, Opportunity, Motivation – Behavior.

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