Empowerment of Family in Early Detection of Total Growth at Puskesmas Karangrejo Metro

The target number of children in early detection of child development and development in the working area of ??Puskesmas Karangrejo is 1,037 children, with details of 133 infants from 0 - 11 months and 904 children aged 12 - 72 months. Of these, the coverage for early detection until February 2020 is still low, namely at 6.7%. The purpose of the Community Service is to empower families in conducting early detection of toddler growth and development in the Karangrejo Health Center area. The method of activity is health education and empowerment of “active participation” of mothers toddler in stimulating and detecting the growth and development of their children. The result of mentoring was that there was progress in the developmental ability of 1 child who had not been able to walk at the age of 19 months, showing an increase in walking ability after 2 weeks of assistance. There was an increase in the knowledge of mothers / families about growth and development by 12.68 points. There was an increase in the frequency of implementing stimulation for child growth and development by mothers of under-five from 88.2% of mothers who had stimulated to 98.6% after mentoring. Continuity of family empowerment is needed regarding early detection of growth and development and not only involving mothers / families but also involving cadres.

State evaluation of some Hydrangea macrophylla (Thunb.) varieties after winter hardiness in the agrometeorological conditions of central Russia

Hydrangea macrophylla (Thunb.) Ser. is one of the most popular ornamental crops, used in landscape design. This article represents the study of the variety resistance of species and influence their of climatic change. In that sense the effective technology of plant shelter for the winter hardiness can be considered as a successful important factor for the promotion of this crop in northern area. Wherefore we consider in a comparative analysis of H. macrophylla varieties Forever & Ever Blue and Peppermint, which we carried out after winter hardiness in the conditions of central Russia. The most reliable and proven way to shelter for winter of hydrangea is the shelter of lutrasil, which contributed to an increase in the viability of shoots and the amount awakened buds, and also provided the better growth of shoots during the month. The highest percentage of overwintered shoots (77,8%), the amount of vegetative and generative buds (19,3±1,3 сm и 9,6±0,7 сm., respectively) and the total growth of shoots in spring (10,2 cm) were characteristic for variety Forever & Ever Blue for using lutrasil as a shelter. Keywords: HYDRANGEA MACROPHYLLA, VARIETIES, WINTER HARDINESS, FROST RESISTANCE, VIABILITY, SHELTER

Effect of a Tea Polyphenol on Different Levels of Exposure of Nicotine and Tobacco Extract on Streptococcus mutans Biofilm Formation

Objective: The purpose of this study was to compare the effects of different levels of nicotine and tobacco extract exposure on Streptococcus mutans biofilm formation and the inhibitory effect of the polyphenol epigallocatechin-3 gallate (EGCG) found in green tea. This study addressed the results of biofilm assays with EGCG and varying relative concentrations of nicotine and tobacco extract consistent with primary, secondary and tertiary levels of smoking exposure. Primary smoking exposure to nicotine has been demonstrated to significantly increase biofilm formation, while EGCG has been demonstrated to reduce S. mutans biofilm formation.Methods:S. mutans was treated with varying levels of nicotine or cigarette smoke condensate (CSC) concentrations (0–32 mg/ml and 0–2 mg/ml, respectively) in Tryptic Soy broth supplemented with 1% sucrose for different lengths of time simulating primary, secondary and tertiary smoking exposure with and without 0.25 mg/ml EGCG. The amount of total growth and biofilm formed was determined using a spectrophotometric crystal violet dye staining assay.Results: For both nicotine and CSC, primary exposure displayed overall significantly less growth compared to secondary exposure. For nicotine, secondary exposure demonstrated significantly greater growth than tertiary exposure levels. Overall, significantly greater total bacterial growth and biofilm formation in the presence of nicotine and CSC was observed in the absence of EGCG than in the presence of EGCG. However, biofilm growth was not significantly different among different concentrations of CSC.Conclusion: The results of this study help illustrate that nicotine-induced S. mutans biofilm formation is reduced by the presence of EGCG. This provides further evidence of the potential beneficial properties of polyphenols.

Remote Sensing in Predicting Development Patterns of Built-up Land

Indonesia is a developing country whose construction and development are centered on the island of Java, especially in West Java Province. Sukabumi City is one of the areas in West Java. The development of urban areas is expanding due to various human needs to carry out the construction of buildings. Remote sensing that can be used to store developments with multi-temporal analysis with materials is Landsat imagery from 2001 to 2020. The method used is the Normalized Difference Built-up Index (NDBI). The purpose of this study is to map the development of the built-up land from year to year and predict the following years. The results of the research on the significant changes in built-up land occurred between 2013-2020, while from 2001 to 2013 there was not much change. Based on the research results, the total growth of built-up land was 1.539% per year with a population growth rate of 1.4% per year. The results of the analysis show that the area of ​​land built in Sukabumi City in 2028 is 186,7194 km2 or has increased by 21,2808 km2 since 2020.

The influence of the mixture of some plant powder with Anacardium occidentale shell liquid smoke on total bacteria and Escherichia coli in the ileum of broiler

Antibiotics/feed additives are commonly used in poultry rations to prevent disease, increase feed efficiency, and improve performance. Plants are the alternatives to replace antibiotics that are safe and without side effects for chicken meat consumers. The aim of this study was to evaluate the effect of administration of a mixture of plant powder and Anacardium occidentale shell liquid smoke on the total bacteria and Escherichia coli in the broiler ileum. The plant mixture was: Phyllanthus niruri L. (PNP) powder: Anacardium occidentale shell liquid smoke (AOLS): Syzygium aromaticum leaf powder (SAP). The study used a Completely Randomized Design. In total, 80 one-day-old broiler chicks were allotted randomly into eight treatments with two replicates per treatment and 5 birds per replicate. The study with the following treatments: Control, Zn-Bacitracin 0.05%, T1 (1.25%: 0.125%: 0.313%), T2 (1.25%: 0.125%: 0.157%), T3 (0.625%: 0.125%: 0.157%). T4 (0.625%: 0.0625: 0.157%), T5 (0.313%: 0.0313: 0.625%), T6 (0.313%: 0.125%: 0.313%). To find out the total bacteria and Escherichia coli, the chicken is then slaughtered 2 hens per replicates to collect feces from the ileum. The results showed that the treatment of the mixture of PNP: AOLS: SAP was not significantly different (P>0.05) with Zn-bacitracin treatment on the total bacteria and Escherichia coli. However, the number of bacteria in T1 was lower than that of the Zn-bacitracin treatment, while the number of Escherichia coli in T1 was closer to the Zn-bacitracin treatment. It can be concluded that the PNP: AOLS: SAP (1.25%: 0.125%: 0.313%) mixture at T1 treatment has the potential as a natural antibiotic to replace Zn-bacitracin antibiotic in inhibiting total growth of bacteria and Escherichia coli in the ileum of broiler.

Analysis of Covid-19 Situation in Udupi District, Karnataka, South India

Background: COVID 19 originated in Wuhan city and rapidlyspread to variouscountries. The first case from India was notified on 30th January at Kerala state. Karnataka identified with COVID cases in the month of March. First case in Udupi notified on 24/03/2020. At the end of August 30 the cases were reached to 11598. Present study aimed to study the trends and pattern of Covid-19 in one of the coastal region of Karnataka i.e. in Udupi district. Objectives: 1) Analyze the trend and pattern of COVID 19 cases at Udupi district. 2) Calculate the incidence, Prevalence, Case Fatality rates and Competed Methodology: Data is obtained from media bulletin released by the Dept.of health and family welfare Karnataka. Udupi district was chosen for studyand data is analyzed throughMS excel and case fatalityrate, Completed case fatality rate, patient recovery rate were calculated and expressed in graphs Result: The case load in increased exponentially but growthrate is droppingdown as month advances. Prevalenceof the cases expressed in Attack rate, CFR, CCFR and PRR. In the month of April attackrate is 1.43 per lakh population, that increased to 88 cases per lakh population.by May, This indicated high susceptible population getting infected. Then it got stabilized around 2-6 folds per month and At the end of August 30 the cases were reached to 11598.In August month fatality rate reaches at peak level with value of 0.9. Total growth in CFR from June to August is 89%. Thecases were high in rainy season when compare to summer season.It indicates climatehas direct effecton the Covid 19 spread in Udupi district Conclusion:The case load in increasing exponentially but growth rate is droppingdown as month advanced in Udupi district indicates better management of cases. Cases got reduced after imposing lockdown in district. Preventive measures and social distancing played an important role in reduction of case load in district.

Breed availability analysis of local beef cattle in Seram Utara Timur Seti District Maluku Tengah Regency

This study aim were to analyze the potential availability of breeds for beef cattle development in Seram Utara Timur Seti District. The research method used was a desk study and survey method. Desk studies were conducted by utilizing relevant secondary data from various related agencies, as well as relevant research results. Meanwhile, surveys and direct observations in the field were carried out in the Animal Husbandry Production Center (KSP) areas, namely Wailoping, Kobisonta and Waitila Village. The variables observed included population structure and potential availability of beef cattle. The results showed that the proportion of the beef cattle population for the categories of calves, youth and adults was 23.18; 22.18 and 54.64% respectively. The sex ratio of male to female in all age categories is still below the normal ratio of 1 male to 5. Total breed growth (net increase) was 70 tails per year from the total population of beef cattle in Seram Utara Timur Seti District (13,032 tails). The total growth of beef cattle is still less than 1% (around 130 heads) of the total population, so it is necessary to pay attention for the development of the source area for beef cattle breeding in Seram Utara Timur Seti District.

Evaluation of antimicrobial and antiproliferative activities of Actinobacteria isolated from the saline lagoons of northwestern Peru

Extreme environments Morrope and Bayovar Salt lagoons, several ecosystems and microhabitats remain unexplored, and little is known about the diversity of Actinobacteria. We suggest that the endemic bacteria present in this extreme environment is a source of active molecules with anticancer, antimicrobial, and antiparasitic properties. Using phenotypic and genotypic characterization techniques, including 16S rRNA sequencing, we identified these bacteria as members of the genera Streptomyces, Pseudonocardia, Staphylococcus, Bacillus, and Pseudomonas. Actinobacteria strains were found predominantly. Phylogenetic analysis revealed 13 Actinobacteria clusters of Streptomyces, the main genus. Three Streptomycetes, strains MW562814, MW562805, and MW562807 showed antiproliferative activities against three tumor cell lines: U251 glioma, MCF7 breast, and NCI-H460 lung (non-small cell type); and antibacterial activity against Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 10536, and the multidrug resistant Acinetobacter baumannii AC-972. The antiproliferative activities (measured as total growth inhibition [TGI]) of Streptomyces sp. MW562807 were 0.57 μg/mL, for 0.61 μg/mL, and 0.80 μg/mL for glioma, lung non-small cell type, and breast cancer cell lines, respectively; the methanolic fraction of the crude extract showed a better antiproliferative activity and could inhibit the growth of (U251 (TGI = 38.3 μg/mL), OVCAR-03 (TGI = 62.1 μg/mL), and K562 (TGI = 81.5 μg/mL)) of nine tumor cells types and one nontumor cell type. Extreme enviroments, such as the Morrope and Bayovar Salt saloons are promising sources of new bacteria, whose compounds may be useful for treating various infectious diseases or even some types of cancer.

A new model of unreported COVID-19 cases outperforms three known epidemic-growth models in describing data from Cuba and Spain

Estimating the unreported cases of Covid-19 in a region/country is a complicated problem. We propose a new mathematical model that, combined with a deterministic model of the total growth of cases, describes the time evolution of the unreported cases for each reported Covid-19 case. The new model considers the growth of unreported cases in plateau periods and the decrease towards the end of an epidemic wave. We combined the new model with a Gompertz-growth model, a generalized logistic model, and a susceptible-infectious-removed (SIR) model; and fitted them via Bayesian methods to data from Cuba and Spain. The combined-model fits yielded better Bayesian-Information-Criterion values than the Gompertz, logistic, and SIR models alone. This suggests the new model can achieve improved descriptions of the evolution of a Covid-19 epidemic wave.