scholarly journals Unusual Drug Fever Caused by Imipenem/Cilastatin and a Review of Literature

2019 ◽  
Vol 22 (2) ◽  
pp. E119-E123 ◽  
Author(s):  
Jie Yang ◽  
Qing Wang ◽  
Suyu Wang ◽  
Yufeng Zhang ◽  
Zhinong Wang

Introduction: Drug fever is a febrile reaction caused by initiation of one drug or varieties of drugs and often disappears after cessation of the drug(s). Clinically, drug fever is frequently induced by antibiotics, anticonvulsants, and antineoplastics. There are few previous reports about drug fever caused by imipenem/cilastatin. Case Presentation: Here, we described a 66-year-old man undergoing the Ivor Lewis esophagectomy for esophageal carcinoma, who developed drug fever. The patient had a high temperature with shivering after administration of imipenem/cilastatin for 7 days. Furthermore, his temperature came down after discontinuing imipenem/cilastatin and receiving steroids. Body temperature increased rapidly 4 hours after intravenous readministration of imipenem/cilastatin and rapidly decreased to normal after discontinuing imipenem/cilastatin and administering steroids. Conclusion: Thorough history, blood tests, physical examination, and computed tomography (CT) did not reveal any evidence of fever. Drug fever caused by imipenem/cilastatin was considered. We also present a review of relevant literature and provide a point of reference for the clinical diagnosis and therapy of patients with drug fever.

2019 ◽  
Vol 101 (1) ◽  
pp. e1-e4 ◽  
Author(s):  
D Schizas ◽  
A Michalinos ◽  
C Vergadis ◽  
D Oikonomou ◽  
E Baili ◽  
...  

Gastric tube conduit is the method of choice for restoring continuity of the digestive track after a partial or total esophagectomy. Redundant gastric conduit (i.e. an elongated, floppy conduit) is a rare cause of dysphagia in patients with long survival. Gastric tube volvulus is exceedingly rare with only three cases described in the literature. We present the diagnostic and therapeutic course of a 57-year-old man who presented to our department with gastric tube volvulus 32 months after an Ivor–Lewis esophagectomy. Diagnosis was made with computed tomography and volvulus was reduced endoscopically. To the best of our knowledge, this is only the fourth case of gastric tube volvulus described in the English literature. This rare situation might be a consequence of a redundant gastric tube. Endoscopic volvulus decompression was successful in our case.


2021 ◽  
Author(s):  
Xiao Wei ◽  
Attigah S. D. Kwasi ◽  
Qi Li ◽  
Hongyan Wu ◽  
Jun Chen ◽  
...  

Abstract Background: Plexiform fibromyxoma (PF) is a very rare mesenchymal tumor of the stomach. Here we report one case of this unusual gastric tumor that was pathologically confirmed after endoscopic resection. Its clinical and pathologic features were observed while the relevant literature was reviewed. Case presentation: A 1.0 cm round elevated submucosal mass was discovered by gastroscopy in a 44-year-old Chinese woman due to recurrent abdominal pain. The tumor was characterized by a multinodular plexiform pattern, bland-looking oval to spindle cells, and a myxoid stroma with thin arborizing capillaries. Immunohistochemistry analysis revealed that the tumor cells were positive for smooth muscle actin (SMA) and negative for CD117, DOG-1, CD34, Desmin, progesterone receptor (PR), CD10, S100 and SOX10. A diagnosis of PF was rendered.Conclusion: Gastric PF is a benign tumor without evidence of local recurrence and distant metastasis. This case emphasizes the unique histological appearance and immunophenotype of PF to promote early diagnosis, while endoscopic resection can be used as an alternative treatment for small and superficial PF.


2020 ◽  
Vol 8 (4) ◽  
pp. 255-260
Author(s):  
Sanaz Mehrabani ◽  

Introduction: Appendicitis could be a rare complication of Salmonella Typhi infection.  Case Presentation: we present a 13-year-old girl with typhoid fever with histology-proven acute appendicitis as a rare complication of Salmonella Typhi infection. The patient was admitted to the hospital with the chief complaints of fever, abdominal pain, diarrhea, and vomiting for more than one week. A brief review of relevant literature was also performed to explore more this rare cause of a common emergency surgical procedure.  Conclusions: In all cases with typhoid fever with persistent diarrhea and vomiting, localized abdominal pain, probable acute appendicitis should be considered as an important complication.


2015 ◽  
Vol 3 (4) ◽  
pp. 165-170
Author(s):  
Ravinder Kumar ◽  
Amit Kumar ◽  
Neha Singh Argahari ◽  
Gagan Jaiswal ◽  
Jyoti Kundu

Hydatid disease is mostly localised to liver and lungs. Cardiac involvement is a rare but potentially very serious complication of echinococcosis, constituting only 0.5–2% of all cases of hydatidosis. Cardiac hydatid cyst is a diagnostic and therapeutic challenge on account of highly variable clinical presentations and non-specifi c symptoms and often numerous unpredictable complications. We present a case report of 20-year-old man who was admitted to our hospital with chief complaint of palpitations and shortness of breath. Using baseline investigations like ECG, transthoracic echocardiography, ultrasonography, non-contrast computed tomography and magnetic resonance imaging, a giant multiloculated cystic lesion (58.4 mm × 43.3 mm) was diagnosed in the apex of left ventricle. Serologic tests (hydatid cyst antibody) confi rmed Echinococcus infection. Thoracic computed tomography with intravenous contrast was not performed because patient reported history of allergy to contrast. This case report is unusual as it is concerned with the description of a rare disease entity (large cardiac hydatid cyst). Its radiological appearances are discussed for early diagnosis and better understanding of the disease, together with a review of the literature.Journal of Kathmandu Medical CollegeVol. 3, No. 4, Oct.-Dec., 2014Page:


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Resul Nusretoğlu ◽  
Yunus Dönder

Abstract Background Diaphragmatic hernias may occur as either congenital or acquired. The most important cause of acquired diaphragmatic hernias is trauma, and the trauma can be due to blunt or penetrating injury. Diaphragmatic hernia may rarely be seen after thoracoabdominal trauma. Case presentation A 54-year-old Turkish male patient admitted to the emergency department with abdominal pain and dyspnea ongoing for 2 days. He had general abdominal tenderness in all quadrants. He had a history of a stabbing incident in his left subcostal region 3 months ago without any pathological findings in thoracoabdominal computed tomography scan. New thoracoabdominal computed tomography showed a diaphragmatic hernia and fluid in the hernia sac. Due to respiratory distress and general abdominal tenderness, the decision to perform an emergency laparotomy was made. There was a 6 cm defect in the diaphragm. There were also necrotic fluids and stool in the hernia sac in the thorax colon resection, and an anastomosis was performed. The defect in the diaphragm was sutured. The oral regimen was started, and when it was tolerated, the regimen was gradually increased. The patient was discharged on the postoperative 11th day. Conclusions Acquired diaphragmatic hernia may be asymptomatic or may present with complications leading to sepsis. In this report, acquired diaphragmatic hernia and associated colonic perforation of a patient with a history of stab wounds was presented.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tsuyoshi Murata ◽  
Yuta Endo ◽  
Shigenori Furukawa ◽  
Atsushi Ono ◽  
Yuichiroh Kiko ◽  
...  

Abstract Background Ovarian abscesses, which occur mostly in sexually active women via recurrent salpingitis, occur rarely in virginal adolescent girls. Here, we present a case of an ovarian abscess in a virginal adolescent girl who was diagnosed and treated by laparoscopy. Case presentation A 13-year-old healthy girl presented with fever lasting for a month without abdominal pain. Computed tomography scan and magnetic resonance imaging indicated a right ovarian abscess. Laparoscopic surgery revealed a right ovarian abscess with intact uterus and fallopian tubes. The abscess was caused by Staphylococcus aureus. The patient recovered completely after excision of the abscess, followed by antibiotic treatment. Conclusions Ovarian abscess may occur in virginal adolescent girls; Staphylococcus aureus, an uncommon species causing ovarian abscess, may cause the infection.


2021 ◽  
Vol 07 (03) ◽  
pp. e124-e126
Author(s):  
Mark Portelli ◽  
Mark Bugeja ◽  
Charles Cini

Abstract Purpose Bochdalek's hernia is a type of congenital diaphragmatic hernia occurring secondary to a defect in the posterior attachment of diaphragm. This condition commonly presents with respiratory insufficiency in infants. To date, there are less than 100 cases of Bochdalek's hernia presenting in adults published in the literature. The mainstay treatment of Bochdalek's hernia involves reduction of hernial contents back into the peritoneal cavity with a tensionless graft repair closing the diaphragmatic defect. Case Presentation We present an atypical case of the Bochdalek hernia presenting in a previously healthy 16-year-old male who presented to the Accident and Emergency department with a 2-day history of dysphagia and loss of breath. The Bochdalek hernia was confirmed on computed tomography (CT) imaging and the patient underwent surgical repair with Gore-Tex mesh. Conclusion The report shows a rare case of the Bochdalek hernia in a young adult, successfully managed with a laparotomy.


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