scholarly journals POTENTIAL BIOCHEMICAL MARKERS OF CHRONIC BRONCHITIS AND BRONCHIAL ASTHMA. CURRENT STATE OF THE PROBLEM

2019 ◽  
Vol 25 (6) ◽  
pp. 624-643 ◽  
Author(s):  
Marie Canton ◽  
Didier Le Gall ◽  
François Feillet ◽  
Chrystele Bonnemains ◽  
Arnaud Roy

AbstractObjective: To provide a comprehensive systematic review of the literature by examining studies published on all cognitive aspects of children with early and continuously treated phenylketonuria (ECT-PKU) included in the databases Medline, PsycINFO, and PsycARTICLE. Method: In addition to a classical approach, we summarized methodology and results of each study in order to discuss current theoretical and methodological issues. We also examined recent advances in biochemical markers and treatments of PKU, with implications for future research on metabolic control and its role as a determinant of neuropsychological outcome. Results: Consistent with previous reviews, the hypothesis of a specific and central executive impairment in children with ECT-PKU was suggested. However, findings are inconclusive regarding the nature of executive impairments as well as their specificity, impact on everyday life, persistence over time, and etiology. Conclusion: Given the current state of the science, we suggest future directions for research that utilizes a developmental and integrative approach to examine the effects of recent advances in biochemical markers and treatment of PKU. (JINS, 2019, 25, 624–643)


2009 ◽  
Vol 173 (6) ◽  
pp. 761-768 ◽  
Author(s):  
H. Arnoldsson ◽  
A. Bouhuys ◽  
S.-E. Lindell

2009 ◽  
Vol 8 (3) ◽  
pp. 11-16 ◽  
Author(s):  
Ye. A. Gereng ◽  
I. V. Sukhodolo ◽  
R. I. Pleshko ◽  
L. M. Ogorodova ◽  
O. Ye. Akbasheva ◽  
...  

In the present research the complex cytologic and biochemical estimation of a condition induced sputum at 19 patients with the heavy therapeutic-sensitive form of a bronchial asthma and 18 patients with chronic obstructive disease of lungs is lead. Dominating morphological and biochemical markers of an asthma became the raised number of macrophages, lymphocytes, and eosinophils at decrease in functional activity neutrophil elastase and increases activation properties. Progressing of destructive and fibrous processes at patients with heavy form chronic obstructive pulmonary disease occurs on a background active neutrophil and lymphocytes reactions in a mucous membrane of bronchial tubes that proves to be true high activity elastase and falling of functioning proteinase inhibitor.


1986 ◽  
Vol 70 (6) ◽  
pp. 565-569 ◽  
Author(s):  
J. Jordanoglou ◽  
G. Tatsis ◽  
Z. Bissiouli

1. In four normal subjects and 51 patients with chronic bronchitis-emphysema, bronchial asthma and pulmonary fibrosis, the VD/VT ratio was measured by a helium washout technique (w VD/VT) and by the conventional Bohr's method using the arterial CO2 tension (VD/VT). 2. In 16 patients the w VD/VT ratio was compared with that calculated from Bohr's equation with the alveolar CO2 tension measured by the rebreathing technique (A VD/VT). 3. It was found that the values for the VD/VT ratio obtained by the helium washout technique were very close to those obtained by the conventional method using the Paco2 or P¯Aco2 values.


1978 ◽  
Vol 72 ◽  
pp. 181-186 ◽  
Author(s):  
I.M. Lightbody ◽  
C.G. Ingram ◽  
J.S. Legge ◽  
R.N. Johnston

The Lancet ◽  
1967 ◽  
Vol 290 (7512) ◽  
pp. 383-384 ◽  
Author(s):  
K.N.V. Palmer ◽  
M.L. Diament

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