scholarly journals THE ROLE OF CYTOKINES IL-4 AND TNFα IN THE PATHOGENESIS OF ACUTE URTICARIA

2017 ◽  
pp. 1-8
Author(s):  
Evgeniya A. Krivonkina ◽  
Alexander M. Bakhirev ◽  
Maria V. Rumyanceva
Keyword(s):  
Acute Urticaria

scholarly journals Interleukin 1-β, Interleukin-1 Receptor Antagonist, and Interleukin 18 in Children with Acute Spontaneous Urticaria

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
E. Machura ◽  
M. Szczepańska ◽  
B. Mazur ◽  
M. Barć-Czarnecka ◽  
A. Kasperska-Zając
Keyword(s):  
Receptor Antagonist ◽  
Healthy Subjects ◽  
Interleukin 1 ◽  
Serum Levels ◽  
Interleukin 18 ◽  
Single Episode ◽  
Acute Urticaria ◽  
Severity Scores ◽  
D Dimer

Very little is known about the role of interleukin-1β(IL-1β) and interleukin-18 (IL-18) in urticaria.Material and Methods. Serum levels of IL-1β, IL-1 receptor antagonist (IL-1RA), and IL-18 were measured in 56 children with urticaria and in 41 healthy subjects.Results. Serum IL-1βdid not differ between children with acute urticaria and controls. Children with single episode of urticaria had higher levels of IL-1RA and IL-18 than healthy subjects. In children with single episode of urticaria, level of IL-1RA correlated with C-reactive protein (CRP), D-dimer, and IL-1βlevels. In subjects with recurrence of urticaria IL-1RA was positively correlated with WBC and D-dimer levels. No correlation of cytokine levels and urticaria severity scores (UAS) in all children with urticaria was observed. In children with single episode of urticaria UAS correlated with CRP level. In the group with single episode of urticaria and in children with symptoms of upper respiratory infection, IL-1RA and IL-18 levels were higher than in controls. The former was higher than in noninfected children with urticaria. In conclusion, this preliminary study documents that serum IL-1RA and IL-18 levels are increased in some children with acute urticaria. However further studies are necessary to define a pathogenic role of IL-1β, IL-1RA, and IL-18 in urticaria.

Outpatient Management of Acute Urticaria: The Role of Prednisone

1995 ◽  
Vol 26 (5) ◽  
pp. 547-551 ◽  
Author(s):  
Charles V Pollack ◽  
Tami J Romano
Keyword(s):  
Outpatient Management ◽  
Acute Urticaria

scholarly journals REMISSION OF A CASE OF MULTIPLE HYMENOPTERA STINGS-ASSOCIATED CHRONIC URTICARIA DURING VENOM IMMUNOTHERPY

2021 ◽  
Author(s):  
Marco Dubini ◽  
Valerio Pravettoni ◽  
Federica Rivolta ◽  
Giulia Segatto ◽  
Riccardo Asero ◽  
...  
Keyword(s):  
Chronic Urticaria ◽  
Venom Immunotherapy ◽  
Acute Urticaria ◽  
Hymenoptera Sting ◽  
Wasp Stings

The role of Immunotherapy in Chronic Urticaria is unclear, except for isolated circumstances. Hymenoptera sting causes acute urticaria and no report of CU after Hymenoptera sting can be found in the literature. We describe a case of onset of CU after multiple wasp stings that remitted during venom immunotherapy.

scholarly journals The role of transcription factor FoxP3 as a predictor of acute and chronic urticaria in children

2021 ◽  
Vol 12 (3) ◽  
pp. 50-54
Author(s):  
S. V. Maltsev ◽  
L. P. Sizyakina ◽  
A. A. Lebedenko
Keyword(s):  
Transcription Factor ◽  
Chronic Urticaria ◽  
Chronic Spontaneous Urticaria ◽  
Immunological Methods ◽  
Control Group ◽  
Acute Urticaria ◽  
Clinical Methods ◽  
Regulatory Lymphocytes

Objective: To study the transcription factor FoxP3 in children with acute and chronic spontaneous urticaria as a possible predictor of the severity and chronicity of urticaria.Materials and Methods: A total of 264 children of both sexes aged from 6 to 16 years old with diff erent variants of urticaria course were examined. Clinical methods of the study included the analysis of anamnestic data and an objective examination of the child with the determination of the severity of urticaria. Immunological methods of the study included the identifi cation of T-regulatory lymphocytes with the CD4+CD25+ Foxp3+CD45+immunophenotype.Results: A signifi cant decrease in the level of transcription factor FoxP3 was found in children with severe acute urticaria and chronic urticaria compared to the control group.Conclusion: Th e degree of reduction in the level of FoxP3 signifi cantly aff ected the likelihood of the development of a severe course of acute urticaria and possible chronization of the disease.

Role of dactinomycin in the improved survival of children with Wilms' tumor

JAMA ◽  
1966 ◽  
Vol 195 (12) ◽  
pp. 1005-1009 ◽  
Author(s):  
D. J. Fernbach
Keyword(s):  
Wilms Tumor

Role of the allergist in diagnosis and management of patients with uveitis

JAMA ◽  
1966 ◽  
Vol 195 (3) ◽  
pp. 167-172 ◽  
Author(s):  
T. E. Van Metre
Keyword(s):  
Diagnosis And Management

The power of norms to sway fused group members

2018 ◽  
Vol 41 ◽  
Author(s):  
Winnifred R. Louis ◽  
Craig McGarty ◽  
Emma F. Thomas ◽  
Catherine E. Amiot ◽  
Fathali M. Moghaddam
Keyword(s):  
Evolutionary Anthropology ◽  
Normative Systems ◽  
Violent Extremism ◽  
Identity Fusion ◽  
Group Members

AbstractWhitehouse adapts insights from evolutionary anthropology to interpret extreme self-sacrifice through the concept of identity fusion. The model neglects the role of normative systems in shaping behaviors, especially in relation to violent extremism. In peaceful groups, increasing fusion will actually decrease extremism. Groups collectively appraise threats and opportunities, actively debate action options, and rarely choose violence toward self or others.

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