Studying the polymerization efficiency of photosensitive compositions by using the surface plasmon resonance method

In a real-time scale, it has been investigated the polymerization process in photosensitive compositions based on oligourethanacrylates with various concentrations of photoinitiators by using the method of surface plasmon resonance. Experimentally determined were the speed of polymerization and induction period for the studied samples of photopolymerization compositions as well as their optimum ratio of components for the chosen illumination wavelength 407 nm. It has been ascertained that with increasing the concentration of photoinitiators Irgacure 651 and Irgacure 819 from 1 up to 2% the speed of polymerization is increased by 3 and 7 times, respectively, while the induction period is decreased by almost 2 and 10 times, respectively. The presence of Irgacure 819 in these compositions provides the highest polymerization speed and the lowest induction period, which is related with the optimal choice of the illumination source wavelength inside the absorption spectrum of initiator, and the competitive absorption in other components of the photopolymer composition is minimal. These investigations are useful for developing optimal compositions of the studied materials for using them in various branches of industry.

Download Full-text

Comparison of sensitivity of the refractometric methods of frustrated total internal reflection and surface plasmon resonance

Izmeritel`naya Tekhnika ◽

10.32446/0369-1025it.2020-2-44-49 ◽

2020 ◽

pp. 44-49

Author(s):

I. N. Pavlov

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Total Internal Reflection ◽

Resonance Method ◽

Internal Reflection ◽

Optical Methods ◽

Thin Boundary Layer ◽

Experimental Conditions ◽

Frustrated Total Internal Reflection

Two optical methods, namely surface plasmon resonance imaging and frustrated total internal reflection, are described in the paper in terms of comparing their sensitivity to change of refractive index of a thin boundary layer of an investigated medium. It is shown that, despite the fact that the theoretically calculated sensitivity is higher for the frustrated total internal reflection method, and the fact that usually in practice the surface plasmon resonance method, on the contrary, is considered more sensitive, under the same experimental conditions both methods show a similar result.

Download Full-text

The use of an engineered single chain variable fragment in a localized surface plasmon resonance method for analysis of the C-reactive protein

Chemical Communications ◽

10.1039/c3cc45046e ◽

2013 ◽

Vol 49 (82) ◽

pp. 9497 ◽

Cited By ~ 19

Author(s):

Ju-Young Byun ◽

Yong-Beom Shin ◽

Taihua Li ◽

Jin-Ho Park ◽

Dong-Myung Kim ◽

...

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Localized Surface Plasmon Resonance ◽

Resonance Method ◽

Localized Surface Plasmon ◽

Single Chain Variable Fragment ◽

Single Chain ◽

C Reactive Protein ◽

Reactive Protein

Download Full-text

Molecular mechanism and thermodynamic study of Rosuvastatin interaction with human serum albumin using a surface plasmon resonance method combined with a multi-spectroscopic, and molecular modeling approach

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2021.106005 ◽

2021 ◽

pp. 106005

Author(s):

Sheida Afkham ◽

Jalal Hanaee ◽

Mostafa Zakariazadeh ◽

Farzaneh Fathi ◽

Samira Shafiee ◽

...

Keyword(s):

Surface Plasmon Resonance ◽

Molecular Modeling ◽

Human Serum Albumin ◽

Serum Albumin ◽

Human Serum ◽

Molecular Mechanism ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Resonance Method ◽

Thermodynamic Study

Download Full-text

Use of a Surface Plasmon Resonance Method To Investigate Antibiotic and Plasma Protein Interactions

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.00971-08 ◽

2009 ◽

Vol 53 (4) ◽

pp. 1528-1531 ◽

Cited By ~ 13

Author(s):

Françoise Banères-Roquet ◽

Maxime Gualtieri ◽

Philippe Villain-Guillot ◽

Martine Pugnière ◽

Jean-Paul Leonetti

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Protein Interactions ◽

Plasmon Resonance ◽

Serum Proteins ◽

Resonance Method ◽

Pharmacologic Effect ◽

Nonspecific Interactions ◽

Automatic Tool ◽

Hit Validation

ABSTRACT The pharmacologic effect of an antibiotic is directly related to its unbound concentration at the site of infection. Most commercial antibiotics have been selected in part for their low propensity to interact with serum proteins. These nonspecific interactions are classically evaluated by measuring the MIC in the presence of serum. As higher-throughput technologies tend to lose information, surface plasmon resonance (SPR) is emerging as an informative medium-throughput technology for hit validation. Here we show that SPR is a useful automatic tool for quantification of the interaction of model antibiotics with serum proteins and that it delivers precise real-time kinetic data on this critical parameter.

Download Full-text