Acute Kidney Injury

Key Points Awareness and early identification are important. Serum creatinine and urine output are key to assessing acute kidney injury. Congenital heart disease, sepsis, and nephrotoxic medications are major causes.

Author(s):  
Fatma Ukil Isildak ◽  
Yasemin Yavuz ◽  
Omer Faruk Savluk ◽  
Nihat Cine ◽  
Ufuk Uslu

Objectives: This study aimed to evaluate whether the development of acute kidney injury (AKI) was associated with preoperative albumin/prealbumin levels and other clinical features in pediatric patients who underwent open-heart surgery for congenital heart disease. Patients and Methods: In this retrospective cohort, patients aged between 1 – 60 months who underwent open-heart surgery (complete correction surgery) with a diagnosis of congenital heart disease at the XXXXXX, between January 1, 2018 - December 31, 2020, were retrospectively included (n = 100). Patient demographics, diagnoses, surgical characteristics, and laboratory findings were recorded and analyzed. Results: Mean age was 13.63 ± 12.05 (range 1.5 - 60) months. eGFR was decreased by more than 50% in 13% of the cases. Compared to the preoperative period, it was found that urea (24th and 48th hour) and creatinine levels increased significantly (p< 0.001, for each), and eGFR decreased significantly in the postoperative period (p< 0.001). Linear regression for eGFR value revealed that longer aortic cross-clamp time (ACCT) was associated with a greater decrease in eGFR (p= 0.046). Other variables included in the model, age (p= 0.128), gender (p= 0.358), RACHS (p= 0.865), body mass index (p= 0.862), prealbumin (p= 0.313), albumin (p= 0.806) and duration of cardiopulmonary bypass (p= 0.921) were found to be non-significant. Conclusion: While there was no relationship between eGFR and preoperative albumin/prealbumin levels in patients who underwent cardiac surgery due to congenital heart disease, longer ACCT was found to be associated with decreased eGFR.


2013 ◽  
Vol 146 (1) ◽  
pp. 146-152 ◽  
Author(s):  
Marnie L. Taylor ◽  
Fabio Carmona ◽  
Ravi R. Thiagarajan ◽  
Lauren Westgate ◽  
Michael A. Ferguson ◽  
...  

2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i340-i340
Author(s):  
Anna Musielak ◽  
Magdalena Silska-Dittmar ◽  
Anna Benedyk ◽  
Danuta Ostalska-Nowicka ◽  
Jacek Zachwieja

2015 ◽  
Vol 6 (3) ◽  
pp. 401-406 ◽  
Author(s):  
Kurt D. Piggott ◽  
Meshal Soni ◽  
William M. Decampli ◽  
Jorge A. Ramirez ◽  
Dianna Holbein ◽  
...  

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