Mortality and Morbidity by Month of Birth of Neonates Admitted to an Academic Neonatal Intensive Care Unit

PEDIATRICS ◽  
2008 ◽  
Vol 122 (5) ◽  
pp. e1048-e1052 ◽  
Author(s):  
T. D. Soltau ◽  
W. A. Carlo ◽  
J. Gee ◽  
J. Gould ◽  
N. Ambalavanan
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Month Of Birth ◽  
Mortality And Morbidity

scholarly journals Clinical Profile and Outcome of Neonates Admitted to Neonatal Intensive Care Unit (NICU) at a Tertiary Care Centre in Eastern Nepal

2013 ◽  
Vol 33 (3) ◽  
pp. 177-181 ◽  
Author(s):  
Gauri Shankar Shah ◽  
Satish Yadav ◽  
Anil Thapa ◽  
Lokraj Shah
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Clinical Profile ◽  
Tertiary Care Centre ◽  
Mortality And Morbidity ◽  
Development Goals

Introduction: Neonatal period is the most susceptible period of life due to different causes, which in most cases are preventable. Every year millions of neonates are born and a large proportion of them are admitted to the neonatal intensive care unit (NICU) for various indications. One of the Millennium Development Goals is to reduce under five mortality by two thirds by 2015. Therefore, this study was conducted to identify the clinical profile, pattern of diseases and common causes of mortality and morbidity in neonates admitted to NICU. Materials and Methods: A retrospective study was conducted at level III Neonatal NICU of a tertiary -care teaching hospital from January, 2012 to December, 2012. Results: Total of 361 neonates were admitted in NICU. Eighty six neonates (23.8%) were admitted due to prematurity and 73 (20.2%) with birth asphyxia. Among birth asphyxia, 40(54.8%)were in HIE III, 27.4% and 17.8% in HIE II and HIE I, respectively. One hundred eighteen (32.6%) cases were diagnosed as sepsis. The overall mortality was 20.2% during hospital stay. Conclusions: Sepsis, prematurity and birth asphyxia were major causes for admission in NICU. All these etiologies are preventable up to some extent and, if detected earlier, can be effectively treated in order to reduce morbidity and mortality. DOI: http://dx.doi.org/10.3126/jnps.v33i3.8447   J. Nepal Paediatr. Soc. 2013;33(3):177-181

scholarly journals Trends in Mortality and Morbidity in Infants Under 500 Grams Birthweight: Observations from Our Neonatal Intensive Care Unit (NICU)

2018 ◽  
Vol 24 ◽  
pp. 4474-4480 ◽  
Author(s):  
Péter Varga ◽  
Botond Berecz ◽  
Barbara Pete ◽  
Timea Kollár ◽  
Zsófia Magyar ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Mortality And Morbidity

scholarly journals Neonatal outcome in neonatal intensive care unit Sanglah Hospital: Assessed by SNAPPE- II score

2021 ◽  
Vol 8 (2) ◽  
pp. 038-044
Author(s):  
Ida Ayu Agung Wijayanti ◽  
Putu Junara Putra ◽  
I Made Kardana ◽  
I Wayan Dharma Artana ◽  
Made Sukmawati
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Length Of Stay ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Mortality ◽  
Neonatal Intensive Care ◽  
Neonatal Outcome ◽  
Antibiotic Usage ◽  
P Value ◽  
Mortality And Morbidity

Neonatal mortality is topic of concern for many medical faculties. Recently Score for Neonatal Acute Physiology with Perinatal Extension-II (SNAPPE-II) is used to predict the mortality and morbidity of neonates in neonatal intensive care unit (NICU). This study aimed to find the association of mortality and morbidity among neonates using SNAPPE-II score in NICU of Sanglah Hospital with cross-sectional design. All newborns admitted in NICU within 48 hours of birth since January - December 2020 were recruited as sample and assessed by using SNAPPE-II. Statistical analysis was performed by using Chi-square test and Mann–Whitney U test. Eighty-three newborns fulfilled inclusion criteria. In the mortality group, 75.6% had SNAPPE score ≥ 37 and 24% had SNAPPE score <37. SNAPPE-II score ≥ 37 showed an association with mortality group in NICU (p-value 0.000). Moreover, subgroup analyst of neonatal outcome in survived group related to SNAPPE-II score showed significant different in length of stay (P=0.033), ventilator usage (P=0.017) and duration of antibiotic usage (P=0.049). The Score for Neonatal Acute Physiology Perinatal Extension II (SNAPPE-II) is a useful tool to assess severity of illness and mortality. SNAPPE-II score > 37 is associated with neonatal mortality. The high SNAPPE-II score in the survived group also affects length of stay in NICU, ventilator and antibiotic usage. These findings imply that SNAPPE-II can be applied routinely in NICU to know the most critical newborn for prioritizing the management of care and for counselling the parents.

scholarly journals Antimicrobial Stewardship in the Neonatal Intensive Care Unit: An Update

2019 ◽  
Vol 15 (1) ◽  
pp. 47-52 ◽  
Author(s):  
Despoina Gkentzi ◽  
Gabriel Dimitriou
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Antimicrobial Stewardship ◽  
Neonatal Intensive Care ◽  
Future Research ◽  
Older Children ◽  
Long Term Effects ◽  
Mortality And Morbidity ◽  
Short And Long Term

Neonates represent a vulnerable population for infections and neonatal sepsis is a major cause of mortality and morbidity worldwide. Therefore, antimicrobials are the most commonly prescribed drugs in the Neonatal Intensive Care Unit Setting but unfortunately are quite often used inappropriately with various short and long-term effects. The rational use of antimicrobials is of paramount importance in this population and structured antimicrobial stewardship interventions should be in place. These interventions are slightly different from those used in adults and older children due to the particularities of the neonatal medicine. The aim of this review is to provide an update in the field and identify areas for further consideration and future research.

Shifting focus toward healthcare-associated bloodstream infections: The need for neonatal intensive care unit–specific NHSN definitions

2019 ◽  
pp. 1-6 ◽  
Author(s):  
Sonali D. Advani ◽  
Thomas S. Murray ◽  
Christina M. Murdzek ◽  
Michael J. Aniskiewicz ◽  
Matthew J. Bizzarro
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Bloodstream Infections ◽  
Mucosal Barrier ◽  
Preterm Neonates ◽  
Site Specific ◽  
Mortality And Morbidity ◽  
Healthcare Associated

Abstract Objective: Healthcare-associated bloodstream infections (HABSIs) are a significant cause of mortality and morbidity in the neonatal intensive care unit (NICU) population. Our objectives were to review the epidemiology of HABSIs in our NICU and to examine the applicability of National Healthcare Safety Network (NHSN) definitions to the NICU population. Methods: We performed a retrospective review of all neonates admitted to the 54-bed, level IV NICU at Yale-New Haven Children’s Hospital with a HABSI between January 1, 2013, and December 31, 2018. Clinical definitions per NICU team and NHSN site-specific definitions used for source identification were compared using the McNemar χ2 test. Results: We identified 86 HABSIs with an incidence rate of 0.80 per 1,000 patient days. Only 13% of these were CLABSIs. Both CLABSIs and non–catheter-related bloodstream infections occurred primarily in preterm neonates, but the latter were associated with a significantly higher incidence of comorbidities and the need for respiratory support. The NHSN definitions were less likely to identify a source compared to the clinical definitions agreed upon by our NICU treating team (P < .001). Furthermore, 50% of patients without an identified source of infection by NHSN definitions were bacteremic with a mucosal barrier injury organism, likely from gut translocation. Conclusions: HABSIs occur primarily in premature infants with comorbidities, and CLABSIs account for a small proportion of these infections. With the increasing focus on HABSI prevention, there is a need for better NHSN site-specific definitions for the NICU population to prevent misclassification and direct prevention efforts.

scholarly journals Pattern of morbidity and mortality among neonates admitted to neonatal intensive care unit in tertiary care centre, western Nepal

2021 ◽  
Vol 14 (1) ◽  
pp. 24-28
Author(s):  
Namrata K.C. ◽  
Bandana Shrestha ◽  
Arjun Bhattarai ◽  
Shankar Paudel ◽  
Nabraj Subedi
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
College Teaching ◽  
Study Data ◽  
Tertiary Care Centre ◽  
Mortality And Morbidity

Background: The objective of this study was to determine the disease pattern and outcome of diseases in neonatal intensive care unit (NICU) as the common causes of mortality and morbidity in our region are preventable. Methods: The retrospective study was carried out in 1041 newborns admitted from 1st August 2019 to 30th July 2020 in Gandaki Medical College Teaching Hospital in Western Nepal. Age, sex, gestational age, diagnosis at admission, outcome of admitted newborns were the main variables under study. Data was entered and analyzed using SPSS 20 version. Result: Among 1041 newborns, 599 (57.54%) were male and 442(42.46%) were female. 1028(98.75%) were born in hospital while 8(0.77%) were born at home and 5(0.48%) in ambulance. The majority 610 newborns were admitted during the first 24 hours of life. Infection and hyperbilirubinemia were the main reasons for admission (44.96% and 23.15 % respectively), followed by prematurity (9.51%) and Birth Asphyxia (9.13%). A total of 831patients (79.83%) were improved and discharged, 79(7.59%) were discharged on request, 61(7.59%) left against medical advice, 34 (3.26) were referred and 36 (3.46%) expired. The major causes for neonatal mortality were prematurity (44.45%), Sepsis (27.78%), and Birth Asphyxia (13.89%) respectively. Among the expired neonates, 24(66.67%) were outborns and 12(33.33%) were inborns and majority 27(75%) expired at the age between 24-48 hours of life. Conclusions: Infection was the leading cause of morbidity and prematurity the leading cause of mortality in the neonatal care unit. This is preventable with antenatal care, training of manpower and procurement of necessary equipments.

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