Amniotic Fluid Infections, Neonatal Hyperbilirubinemia, and Psychomotor Impairment

PEDIATRICS ◽  
1978 ◽  
Vol 62 (4) ◽  
pp. 497-503 ◽  
Author(s):  
Richard L. Naeye

A large prospective study found that infants born with evidence of recent amniotic fluid infections subsequently had an increased frequency of mental, motor, visual, and hearing impairment. These infections also potentiated the neurotoxicity of neonatal hyperbilirubinemia. This potentiation of bilirubin neurotoxicity increased with the severity of the amniotic fluid infections. With or without such infections, an increased frequency of long-term mild mental retardation started at peak neonatal bilirubin levels of only 7 mg/dl in both term and preterm infants. Significant neurologic abnormalities began at peak bilirubin levels of 12 to 13 mg/dl.

1994 ◽  
Vol 61 (3) ◽  
pp. 282-300 ◽  
Author(s):  
Phyllis Levine ◽  
Eugene Edgar

This study analyzed gender differences in postschool outcomes for youth with learning disabilities, mild mental retardation, and no disabilities. Data were collected on two cohorts of graduates (549 youth who were graduated in 1985; 398 youth, in 1990) from three school districts. Data were collected at 1, 2, 6, and 7 years postgraduation. Comparisons were made between genders within disability groups on employment, postsecondary education attendance and graduation, engagement, independent living, marital status, and parenting. In contrast to the findings of other studies, few significant differences were noted between genders, except for the parenting category. A similar analysis between youth by disability category resulted in considerably more significant differences.


2016 ◽  
Vol 193 (10) ◽  
pp. 1134-1142 ◽  
Author(s):  
Michelle C. Turner ◽  
Michael Jerrett ◽  
C. Arden Pope ◽  
Daniel Krewski ◽  
Susan M. Gapstur ◽  
...  

2014 ◽  
Vol 104 (1) ◽  
pp. 30-33 ◽  
Author(s):  
Ulrich Illgner ◽  
Tymo Budny ◽  
Marc Hoyer ◽  
Hans Henning Wetz

Background For several years, confectioned or customized interdigital silicone orthoses have been used to treat toe malformations; however, long-term clinical and biomechanical studies are missing. The aim of this study was to evaluate the biomechanical effects of these orthoses and their clinical acceptance. Methods In 2008, 46 patients (30 women and 16 men; average age, 56.8 years) received interdigital silicone orthoses. All of the patients were included in the biomechanical and clinical study. Compliance and acceptance were measured by the Muenster shoe and foot questionnaire, which includes 13 items on pain, activities of daily living, satisfaction, and activity. Mean follow-up was 18 months. Ten feet (eight patients) were chosen by random and underwent pedobarography. One forefoot sensor and two single sensors were attached between the skin and the orthosis. Measurements were performed in-shoe three times with and without the orthosis without removal of the sensors. Results Forty-four of the 46 patients (95.7%) were included. At the 18-month investigation, 19 patients no longer used their orthoses, most commonly because of pain and failure of the material. Twenty-two patients regularly used their orthoses (8 h/d on average). In-shoe peak pressure lowered significantly with orthosis use (P < .04). Patients who used the orthoses were mostly satisfied. Conclusions Interdigital silicone orthoses reduce in-shoe peak pressure. Patient satisfaction was good. The durability of the material has to be optimized, and manufacturing remains difficult. The effect on ulcer reduction must be evaluated in a large prospective study.


2012 ◽  
Vol 8 (3) ◽  
pp. 320-323 ◽  
Author(s):  
Nasser Simforoosh ◽  
Ali Tabibi ◽  
Seyed Ali Reza Khalili ◽  
Mohammad Hossein Soltani ◽  
Abolfazl Afjehi ◽  
...  

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