Psychological Development of Children Who Were Treated Antenatally With Corticosteroids to Prevent Respiratory Distress Syndrome

Potential side effects of antenatal administration of corticosteroids to prevent neonatal respiratory distress syndrome were studied in 10- to 12-year-old children whose mothers had participated in a randomized, double-blind, placebo-controlled trial of betamethasone. Aspects of the children's intellectual and motor development, school achievement, and social-emotional functioning were investigated. There were no differences between the corticoid group and the placebo group on these variables, nor were there more children with learning difficulties and behavioral disturbances in either of the groups.

Download Full-text

Physical Development and Medical History of Children Who Were Treated Antenatally With Corticosteroids to Prevent Respiratory Distress Syndrome: A 10- to 12-Year Follow-up

PEDIATRICS ◽

10.1542/peds.86.1.65 ◽

1990 ◽

Vol 86 (1) ◽

pp. 65-70 ◽

Cited By ~ 2

Author(s):

H. Smolders-de Haas ◽

J. Neuvel ◽

B. Schmand ◽

p. E. Treffers ◽

J. G. Koppe ◽

...

Keyword(s):

Infectious Diseases ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Medical History ◽

Distress Syndrome ◽

Hospital Admissions ◽

Controlled Trial ◽

Ophthalmological Examination ◽

Double Blind ◽

History Of

Potential side effects of antenatal administration of corticosteroids to prevent neonatal respiratory distress syndrome were studied in 10- to 12-year-old children whose mothers had participated in a randomized, double-blind, placebo-controlled trial of betamethasone. The children had a general physical examination; parents were interviewed about the medical history of their child with special attention to infectious diseases; growth data were collected; and a developmental neurological examination, an ophthalmological examination, and a lung function test were conducted. In the corticosteroid group significantly more hospital admissions because of infectious diseases during the first years of life were reported. On the other variables no differences between the corticoid and the placebo groups were found.

Download Full-text

Full versus half dose of antenatal betamethasone to prevent severe neonatal respiratory distress syndrome associated with preterm birth: study protocol for a randomised, multicenter, double blind, placebo-controlled, non-inferiority trial (BETADOSE)

BMC Pregnancy and Childbirth ◽

10.1186/s12884-019-2206-x ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 5

Author(s):

Thomas Schmitz ◽

◽

Corinne Alberti ◽

Moreno Ursino ◽

Olivier Baud ◽

...

Keyword(s):

Preterm Birth ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Study Protocol ◽

Distress Syndrome ◽

Neonatal Respiratory Distress Syndrome ◽

Double Blind ◽

Double Blind Placebo ◽

Half Dose ◽

Neonatal Respiratory Distress

Download Full-text

A multicentre, randomised, double-blind, placebo-controlled trial to evaluate intravenous infusion of salbutamol versus saline for 28-day mortality in patients with acute respiratory distress syndrome

http://isrctn.org/> ◽

10.1186/isrctn38366450 ◽

2013 ◽

Author(s):

Fang Gao

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Intravenous Infusion ◽

Distress Syndrome ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo

Download Full-text

Vaginal progesterone pessaries for pregnant women with a previous preterm birth to prevent neonatal respiratory distress syndrome (the PROGRESS Study): A multicentre, randomised, placebo-controlled trial

PLoS Medicine ◽

10.1371/journal.pmed.1002390 ◽

2017 ◽

Vol 14 (9) ◽

pp. e1002390 ◽

Cited By ~ 22

Author(s):

Caroline A. Crowther ◽

Pat Ashwood ◽

Andrew J. McPhee ◽

Vicki Flenady ◽

Thach Tran ◽

...

Keyword(s):

Preterm Birth ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Pregnant Women ◽

Distress Syndrome ◽

Controlled Trial ◽

Neonatal Respiratory Distress Syndrome ◽

Vaginal Progesterone ◽

Neonatal Respiratory Distress

Download Full-text

A randomized, controlled trial of oral and intramuscular dexamethasone in the prevention of neonatal respiratory distress syndrome

American Journal of Obstetrics and Gynecology ◽

10.1016/s0002-9378(98)70116-4 ◽

1998 ◽

Vol 179 (5) ◽

pp. 1120-1123 ◽

Cited By ~ 32

Author(s):

Robert S. Egerman ◽

Brian M. Mercer ◽

Jennifer L. Doss ◽

Baha M. Sibai

Keyword(s):

Randomized Controlled Trial ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Controlled Trial ◽

Neonatal Respiratory Distress Syndrome ◽

Randomized Controlled ◽

Neonatal Respiratory Distress

Download Full-text

Neonatal Respiratory Distress Syndrome After Repeat Exposure to Antenatal Corticosteroids: A Randomized Controlled Trial

Obstetrical & Gynecological Survey ◽

10.1097/01.ogx.0000243896.75055.74 ◽

2006 ◽

Vol 61 (11) ◽

pp. 691-693 ◽

Cited By ~ 2

Author(s):

Caroline A. Crowther ◽

Ross R. Haslam ◽

Janet E. Hiller ◽

Lex W. Doyle ◽

Jeffrey S. Robinson

Keyword(s):

Randomized Controlled Trial ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Controlled Trial ◽

Neonatal Respiratory Distress Syndrome ◽

Antenatal Corticosteroids ◽

Randomized Controlled ◽

Neonatal Respiratory Distress ◽

Repeat Exposure

Download Full-text

Faculty Opinions recommendation of Neonatal respiratory distress syndrome after repeat exposure to antenatal corticosteroids: a randomised controlled trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14251.472086 ◽

2006 ◽

Author(s):

Ibrahim Bildirici

Keyword(s):

Randomised Controlled Trial ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Controlled Trial ◽

Neonatal Respiratory Distress Syndrome ◽

Antenatal Corticosteroids ◽

Neonatal Respiratory Distress ◽

Repeat Exposure ◽

Randomised Controlled

Download Full-text

Randomised controlled trial of patient triggered and conventional fast rate ventilation in neonatal respiratory distress syndrome

Archives of Disease in Childhood - Fetal and Neonatal Edition ◽

10.1136/fn.82.1.f14 ◽

2000 ◽

Vol 82 (1) ◽

pp. F14-F18 ◽

Cited By ~ 36

Author(s):

M W Beresford ◽

N J Shaw ◽

D Manning

Keyword(s):

Randomised Controlled Trial ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Fast Rate ◽

Controlled Trial ◽

Neonatal Respiratory Distress Syndrome ◽

Neonatal Respiratory Distress ◽

Randomised Controlled

Download Full-text

Progesterone after previous preterm birth for prevention of neonatal respiratory distress syndrome (PROGRESS): a randomised controlled trial

BMC Pregnancy and Childbirth ◽

10.1186/1471-2393-9-6 ◽

2009 ◽

Vol 9 (1) ◽

Cited By ~ 18

Author(s):

Jodie M Dodd ◽

Caroline A Crowther ◽

Andrew J McPhee ◽

Vicki Flenady ◽

Jeffrey S Robinson

Keyword(s):

Preterm Birth ◽

Randomised Controlled Trial ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Controlled Trial ◽

Neonatal Respiratory Distress Syndrome ◽

Neonatal Respiratory Distress ◽

Randomised Controlled

Download Full-text

Novel Adjuvant Therapy with Zinc Supplementation in Neonatal Respiratory Distress Syndrome

Endocrine Metabolic & Immune Disorders - Drug Targets ◽

10.2174/1871530321666210729113515 ◽

2021 ◽

Vol 21 ◽

Author(s):

Mohamed Shawky Elfarargy ◽

Ghada M Al-Ashmawy ◽

Sally Abu-Risha ◽

Haidy Khattab

Keyword(s):

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Controlled Trial ◽

Neonatal Respiratory Distress Syndrome ◽

Prospective Randomized Controlled Trial ◽

Neonatal Respiratory Distress ◽

Duration Of Hospitalization ◽

Group 2 ◽

Group 1

Background: Neonatal respiratory distress syndrome (RDS) is a common dangerous chest problem that is caused by a lack of surfactant. Aim: The aim of this study was to show the role of zinc as an adjuvant anti-inflammatory therapy in neonatal RDS. Methods: A prospective randomized controlled trial (RCT) study was done on 90 neonates suffering from respiratory distress (RD) who had been diagnosed as RDS. The included neonates were classified into two groups: group 1, which received Zinc (Zn) supplementation, and group 2, which received a placebo. Down score, grades of RDS Malondialdehyde (MDA), Superoxide Dismutase (SOD) andInterleukin-8 (IL-8) were estimated on the 1st and 5th day in the presence of incubators. Results: There were statistically significant differences (SSD) in grades of RDS, Down score, MDA, SOD and IL-8 on the 5th day between group 1 and 2(p = 0.001), and between 1st and 5th day in group 1 (p = 0.001) in the presence of an incubator. There was an SSD between groups 1 and 2 in the duration of hospitalization (p = 0.001) and the number of cases that needed mechanical ventilation (MV) (p = 0.049). Conclusion: Zn supplementation is associated with clinical and laboratory improvement in cases of neonatal RDS. Recommendation: Zn supplementation for RDS neonates.

Download Full-text